Results 61 to 70 of about 2,536,783 (302)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Prediction of the water solubility by a graph convolutional-based neural network on a highly curated dataset

open access: yesJournal of Cheminformatics
Water solubility is a relevant physico-chemcial property in environmental chemistry, toxicology, and drug design. Although the water solubility is besides the octanol–water partition coefficient, melting point, and boiling point a property with a large ...
Nadin Ulrich   +4 more
doaj   +1 more source

All that is silver is not toxic: silver ion and particle kinetics reveals the role of silver ion aging and dosimetry on the toxicity of silver nanoparticles

open access: yesParticle and Fibre Toxicology, 2018
Background When suspended in cell culture medium, nano-objects composed of soluble metals such as silver can dissolve resulting in ion formation, altered particle properties (e.g. mass, morphology, etc.), and modulated cellular dose.
Jordan N. Smith   +9 more
doaj   +1 more source

Atmospheric oxidation of isoprene and 1,3-butadiene: influence of aerosol acidity and relative humidity on secondary organic aerosol [PDF]

open access: yesAtmospheric Chemistry and Physics, 2015
The effects of acidic seed aerosols on the formation of secondary organic aerosol (SOA) have been examined in a number of previous studies, several of which have observed strong linear correlations between the aerosol acidity (measured as nmol H+ m−3 air
M. Lewandowski   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Fixture for environmental exposure of structural materials under compression load [PDF]

open access: yes, 1983
A device for stressing a deformable material specimen consists of top plate and a bottom plate sandwiching a guide cylinder. The specimen is positioned on the bottom plate and attached to a load piston.
Clark, R. K., Lisagor, W. B.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Immunoprevalence to Six Waterborne Pathogens in Beachgoers at Boquerón Beach, Puerto Rico: Application of a Microsphere-Based Salivary Antibody Multiplex Immunoassay

open access: yesFrontiers in Public Health, 2017
Waterborne infectious diseases are a major public health concern worldwide. Few methods have been established that are capable of measuring human exposure to multiple waterborne pathogens simultaneously using non-invasive samples such as saliva.
Swinburne A. J. Augustine   +12 more
doaj   +1 more source

Environmental Exposures and Kidney Disease

open access: yesKidney360, 2022
Accumulating evidence underscores the large role played by the environment in the health of communities and individuals. We review the currently known contribution of environmental exposures and pollutants on kidney disease and its associated morbidity. We review air pollutants, such as particulate matter; water pollutants, such as trace elements, per-
Abhijit V. Kshirsagar   +4 more
openaire   +2 more sources

Reading, Writing, and Breathing [PDF]

open access: yes, 2005
This report looks at the distribution of air toxics, respiratory hazard, and school children in the state of California. The report finds evidence of disproportionate exposure and a potential link between such exposure and school-level academic ...
James Sadd   +2 more
core  

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