Results 61 to 70 of about 1,123,096 (314)

Medium-Term Lag-Response Associations Between PM10 Exposure and All-Cause Mortality in Valencia and London: A Time-Stratified Case-Crossover Study

Journal of Epidemiology and Global Health
Background Air pollution is among the top five environmental risk factors for human health worldwide. However, our understanding of the physiological responses to PM10 exposure over medium-term lag periods remains limited.
Bin Zhou, Katrin Gohlsch, Surendra Ranpal, Jiancong Wang, Christoph Knote   +4 more
doaj   +1 more source

Updates to the Noah Land Surface Model in WRF‐CMAQ to Improve Simulated Meteorology, Air Quality, and Deposition

Journal of Advances in Modeling Earth Systems, 2019
Regional, state, and local environmental regulatory agencies often use Eulerian models to investigate the potential impacts on pollutant deposition and air quality from changes in land use, anthropogenic and natural emissions, and climate.
Patrick C. Campbell, Jesse O. Bash, Tanya L. Spero   +2 more
doaj   +1 more source

The formation of secondary organic aerosol from the isoprene + OH reaction in the absence of NO_x [PDF]

Atmospheric Chemistry and Physics, 2009
The reaction of isoprene (C5H8) with hydroxyl radicals has been studied in the absence of nitrogen oxides (NOx) to determine physical and chemical characteristics of the secondary organic aerosol formed.
T. E. Kleindienst, M. Lewandowski, J. H. Offenberg, M. Jaoui, E. O. Edney   +4 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Regional Air Quality Model Application of the Aqueous-Phase Photo Reduction of Atmospheric Oxidized Mercury by Dicarboxylic Acids

Atmosphere, 2013
In most ecosystems, atmospheric deposition is the primary input of mercury. The total wet deposition of mercury in atmospheric chemistry models is sensitive to parameterization of the aqueous-phase reduction of divalent oxidized mercury (Hg2+).
Jesse O. Bash, Annmarie G. Carlton, William T. Hutzell, O. Russell Bullock Jr.   +3 more
doaj   +1 more source

Assessment of long-term WRF–CMAQ simulations for understanding direct aerosol effects on radiation "brightening" in the United States [PDF]

Atmospheric Chemistry and Physics, 2015
Long-term simulations with the coupled WRF–CMAQ (Weather Research and Forecasting–Community Multi-scale Air Quality) model have been conducted to systematically investigate the changes in anthropogenic emissions of SO2 and NOx over the past 16 years ...
C.-M. Gan, J. Pleim, R. Mathur, C. Hogrefe, C. N. Long, J. Xing, D. Wong, R. Gilliam, C. Wei   +8 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Fourth national report on human exposure to environmental chemicals: updated tables, August 2014 [PDF]

The Fourth National Report on Human Exposure to Environmental Chemicals, Updated Tables, August 2014 provides nationally representative biomonitoring data that has become available since the publication of the Fourth National Report on Human Exposure to ...

core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source