Results 21 to 30 of about 3,213,823 (263)

Stemness of Normal and Cancer Cells: The Influence of Methionine Needs and SIRT1/PGC-1α/PPAR-α Players

open access: yesCells, 2022
Stem cells are a population of undifferentiated cells with self-renewal and differentiation capacities. Normal and cancer stem cells share similar characteristics in relation to their stemness properties.
Youssef Siblini   +4 more
doaj   +1 more source

Distribution and Causes of Global Forest Fragmentation

open access: yesEcology and Society, 2003
Because human land uses tend to expand over time, forests that share a high proportion of their borders with anthropogenic uses are at higher risk of further degradation than forests that share a high proportion of their borders with non-forest, natural ...
Timothy G. Wade   +3 more
doaj   +1 more source

High-throughput toxicogenomic screening of chemicals in the environment using metabolically competent hepatic cell cultures

open access: yesnpj Systems Biology and Applications, 2021
The ToxCast in vitro screening program has provided concentration-response bioactivity data across more than a thousand assay endpoints for thousands of chemicals found in our environment and commerce.
Jill A. Franzosa   +12 more
doaj   +1 more source

Extending the Community Multiscale Air Quality (CMAQ) modeling system to hemispheric scales: overview of process considerations and initial applications [PDF]

open access: yesAtmospheric Chemistry and Physics, 2017
The Community Multiscale Air Quality (CMAQ) modeling system is extended to simulate ozone, particulate matter, and related precursor distributions throughout the Northern Hemisphere.
R. Mathur   +11 more
doaj   +1 more source

Lead levels of new solvent-based household paints in Zimbabwe and Botswana: A preliminary study

open access: yesAfrican Journal of Primary Health Care & Family Medicine, 2022
Background: Lead paint remains a major potential source of lead poisoning globally, but there has been no documentation on lead content in solvent paints available on the markets in Zimbabwe and Botswana.
Rose A. Kambarami   +6 more
doaj   +1 more source

Short-Term Transcriptomic Points of Departure Are Consistent with Chronic Points of Departure for Three Organophosphate Pesticides across Mouse and Fathead Minnow

open access: yesToxics, 2023
New approach methods (NAMs) can reduce the need for chronic animal studies. Here, we apply benchmark dose (concentration) (BMD(C))–response modeling to transcriptomic changes in the liver of mice and in fathead minnow larvae after short-term exposures (7
Rubia Martin   +4 more
doaj   +1 more source

Global-Scale Patterns of Forest Fragmentation

open access: yesEcology and Society, 2000
We report an analysis of forest fragmentation based on 1-km resolution land-cover maps for the globe. Measurements in analysis windows from 81 km 2 (9 x 9 pixels, "small" scale) to 59,049 km 2 (243 x 243 pixels, "large" scale) were used to characterize ...
Kurt Riitters   +4 more
doaj   +1 more source

Modeling stratospheric intrusion and trans-Pacific transport on tropospheric ozone using hemispheric CMAQ during April 2010 – Part 2: Examination of emission impacts based on the higher-order decoupled direct method [PDF]

open access: yesAtmospheric Chemistry and Physics, 2020
The state-of-the-science Community Multiscale Air Quality (CMAQ) modeling system, which has recently been extended for hemispheric-scale modeling applications (referred to as H-CMAQ), is applied to study the trans-Pacific transport, a phenomenon ...
S. Itahashi   +5 more
doaj   +1 more source

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