Environmental and Molecular Mutagenesis, EarlyView.Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl +14 more
wiley +1 more source
Rivers of Tears - Convergent, Multi-Scale Approaches to Monitor and Optimize the Health of Our World's Inhabitants. [PDF]
Glob ChallAnderson EJ +6 more
europepmc +1 more source
Lung carcinogenicity by whole body inhalation exposure to Anatase-type Nano-titanium Dioxide in rats
Tatsuya Kasai +10 more
openalex +2 more sources
Report on Carcinogens Monograph on Helicobacter pylori (Chronic Infection) [PDF]
, 2018 National Toxicology Program (NTP)
openalex +1 more source
Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines
Environmental and Molecular Mutagenesis, EarlyView.ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li +7 more
wiley +1 more source
SIRT3-IDH2 axis is a target of dietary fructose: implication of IDH2 as a key player in dietary carcinogen toxicity in mice colon. [PDF]
Exp Mol MedPan JH +9 more
europepmc +1 more source
A multi‐level approach for multi‐objective optimization in process eco‐design
Environmental Progress &Sustainable Energy, EarlyView.Abstract This work addresses a central challenge in process eco‐design: how to efficiently integrate environmental and economic criteria—often conflicting—into early design stages while managing the high dimensionality of Life Cycle Assessment (LCA) indicators.
Luis Fernando Morales‐Mendoza +3 more
wiley +1 more source
Cancer Chemo-Preventive Potential of Calligonum polygonoides Stem Extract Against DMBA Induced Skin Carcinogenesis. [PDF]
Asian Pac J Cancer PrevMeghwal GP +5 more
europepmc +1 more source
Current Advancements of Probiotic Foods and Their Role in Sustainable Food Security
Food Bioengineering, EarlyView.ABSTRACT Probiotic foods have evolved from traditional fermented products to scientifically validated functional foods, defined by the FAO and WHO as live microorganism that confer a health benefit on the host when administered in adequate amounts, with effects being strain, does and end point specific.
Ashenafi Teklay Yaekob +3 more
wiley +1 more source
It's a gator tale: Alligator lung cells resist hexavalent chromium-induced DNA repair inhibition and chromosome instability. [PDF]
J Trace Elem Med BiolWilliams AR, Diven SS, Meaza I, Wise JP.
europepmc +1 more source