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Two monstrous female health-related issues are currently engaging the attention of the global community. These are the chemical skin-lightening issue and the rising female breast cancer issue.
Yetunde M. Olumide+8 more
doaj +1 more source
Oxidative Stress in the Carcinogenicity of Chemical Carcinogens [PDF]
This review highlights several in vivo studies utilizing non-genotoxic and genotoxic chemical carcinogens, and the mechanisms of their high and low dose carcinogenicities with respect to formation of oxidative stress. Here, we survey the examples and discuss possible mechanisms of hormetic effects with cytochrome P450 inducers, such as phenobarbital, a-
Anna Kakehashi+3 more
openaire +2 more sources
Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure [PDF]
Hepatocellular carcinoma (HCC) is characterized by the accumulation of unfolded proteins in the endoplasmic reticulum (ER), which activates the unfolded protein response (UPR).
Ampe, Christophe+16 more
core +3 more sources
Cytochromes P450 are Expressed in Proliferating Cells in Barrett's Metaplasia
The expression of cytochromes P450 (CYP) in Barrett's esophagus and esophageal squamous mucosa was investigated. Esophagectomy specimens from 23 patients were examined for CYP expression of CYP1A2, CYP3A4, CYP2C9/10, and CYP2E1 by immunohistochemical ...
Steven J. Hughes+7 more
doaj +1 more source
Specific gene and miRNA expression patterns are potential early biomarkers of harmful environmental carcinogen exposures. The aim of our research was to develop an assay panel by using several miRNAs for the rapid screening of potential carcinogens.
Andras Tomesz+13 more
doaj +1 more source
Millions of people have tattoos. The systemic effects of tattoo colorants (TCs) are mostly unknown. Several tattoos are on the market, which contain carcinogenic compounds such as poly aromatic hydrocarbons compounds or carcinogenic aromatic amines.
Sabbioni, Gabriele, Hauri, Urs
openaire +3 more sources
High efficient catalytic degradation of tetracycline and ibuprofen using visible light driven novel Cu/Bi2Ti2O7/rGO nanocomposite::Kinetics, intermediates and mechanism [PDF]
The photoexcited charge carriers trapping was an effective way to generate a large number of active species like O-2(center dot-) and (OH)-O-center dot radicals to oxidize pharmaceutical molecules.
Acevedo, R.+4 more
core +1 more source
Cytochrome P450 enzyme systems have been widely used in vitro to determine the pathways of activation of procarcinogens, but paradoxically, these same enzymes can play a more predominant role in carcinogen detoxification in vivo.
Lindsay Reed, V. Arlt, D. Phillips
semanticscholar +1 more source
A toxicity electrochemical DNA biosensor has been constructed for the detection of carcinogens using 24 base guanine DNA rich single stranded DNA, and methylene blue (MB) as the electroactive indicator.
Nor Diyana Md. Sani+7 more
doaj +1 more source
Nasal cavity tumors constitute a very small part of head and neck malignancies. Although paranasal sinus tumors due to the presence of backward foreign bodies, neoplasms of nasal cavity associated with a foreign body are extremely rare.
Selçuk Yıldız+3 more
doaj +1 more source