Results 41 to 50 of about 77,097 (309)

Carcinogenic Mycotoxins*

open access: yes, 2010
Mycotoxins are metabolites of molds considered to be a major risk factor affecting human and animal health. It is estimated that 25% of the world’s crop production is contaminated with mycotoxins. Mold contamination occurs extensively in fields and is particularly severe in tropical countries.
Peraica, Maja, Domijan, Ana-Marija
openaire   +2 more sources

Predicting residential radon concentrations in Finland: Model development, validation, and application to childhood leukemia

open access: yesScandinavian Journal of Work, Environment & Health, 2020
OBJECTIVES: Inhaled radon gas is a known alpha-emitting carcinogen linked especially to lung cancer. Studies on higher concentrations of indoor radon and childhood leukemia have conflicting but largely negative results.
Atte Nikkilä   +6 more
doaj   +1 more source

DNA-Carcinogen Adducts in Circulating Leukocytes as Indicators of Arylamine Carcinogen Exposure

open access: yes, 1993
DNA-Carcinogen Adducts in Circulating Leukocytes as Indicators of Arylamine Carcinogen Exposure. Levy, G. N. (1993). Fundam. Appl. Toxicol. 21, 23-30.DNA-carcinogen adducts in leukocytes and putative target tissues (liver and urinary bladder) of C57BL/6J
Levy, Gerald N.
core   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Pluronic F68 block polymer, a very potent suppressor of carcinogenesis in the colon of rats and mice [PDF]

open access: yes, 2001
Polyethylene-glycol (PEG) is a strong inhibitor of colon cancer in rats, and the most potent suppressor of aberrant crypt foci. Nine PEG-like block copolymers were tested in rodents, after an azoxymethane injection.
Peiffer, Ginette   +5 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Mouse Models for Application in Colorectal Cancer: Understanding the Pathogenesis and Relevance to the Human Condition

open access: yesBiomedicines, 2022
Colorectal cancer (CRC) is a malignant disease that is the second most common cancer worldwide. CRC arises from the complex interactions among a variety of genetic and environmental factors. To understand the mechanism of colon tumorigenesis, preclinical
Chuangen Li   +3 more
doaj   +1 more source

Cigarette-Specific Carcinogen Induces Stabilization of DNA methyltransferases through AKT/GSK3β/βTrCP Pathway in Lung Cancer [PDF]

open access: yes, 2011
[[abstract]]Background: Most lung cancer cases are caused by cigarette-specific carcinogens, such as nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Previous studies have shown that NNK induces promoter hypermethylation of several tumor
Yi-Shuan Hsieh, 謝翊萱
core  

Clinical assessment to screen for the detection of oral cavity cancer and potentially malignant disorders in apparently healthy adults [PDF]

open access: yes, 2012
The objective of this review is to estimate the accuracy of the conventional oral examination (COE) used singly or in combination with another index test (Additional Table 1) as a screening test for the detection of oral cancer and potentially malignant ...
Liu, JLY   +29 more
core   +1 more source

Direct Metal Deposition of Graphene–Ti28Nb35.4Zr Matrix Composites With Enhanced Mechanical, Corrosion, and Biocompatibility Properties for Bone Implants

open access: yesAdvanced Engineering Materials, EarlyView.
Graphene nanoplatelet (0.1 wt.%) reinforcement significantly enhances the performance of β Ti‐28Nb‐35.4Zr alloy. Grain refinement, reduced water contact angle, and improved surface characteristics promote osteoblast adhesion and complete surface coverage after 7 days.
Khurram Munir   +5 more
wiley   +1 more source

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