Results 231 to 240 of about 170,355 (359)

Malignization In Vitro of Hamster Embryonic Cells by Chemical Carcinogens

, 1966
Haruo Sato, Toshio Kuroki
openalex   +2 more sources

Evaluation of the standard battery of in vitro genotoxicity tests to predict in vivo genotoxicity through mathematical modeling: A report from the 8th International Workshop on Genotoxicity Testing

Environmental and Molecular Mutagenesis, EarlyView.
Abstract In human health risk assessment of chemicals and pharmaceuticals, identification of genotoxicity hazard usually starts with a standard battery of in vitro genotoxicity tests, which is needed to cover all genotoxicity endpoints. The individual tests included in the battery are not designed to pick up all endpoints.
Mirjam Luijten, Jan van Benthem, Takeshi Morita, Raffaella Corvi, Patricia A. Escobar, Yurika Fujita, Jennifer Hemmerich, Naveed Honarvar, David Kirkland, Naoki Koyama, David P. Lovell, Miriam Mathea, Andrew Williams, Stephen Dertinger, Stefan Pfuhler, Jeroen L. A. Pennings   +15 more
wiley   +1 more source

Development of Korean CARcinogen EXposure: IARC Group 2A Carcinogens. [PDF]

Saf Health Work
Koh DH, Choi S, Park JH, Lee SG, Kim HC, Kim I, Min J, Kim Y, Lee J, Park DU.   +9 more
europepmc   +1 more source

REACTION OF CARCINOGENS WITH ACRIDINE

, 1961
A. Szent-Györgyi, Jane R. McLaughlin
openalex   +1 more source

Consensus findings of an International Workshops on Genotoxicity Testing workshop on using transcriptomic biomarkers to predict genotoxicity

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl, J. Christopher Corton, Henghong Li, Jiri Aubrecht, Scott S. Auerbach, Florian Caiment, Tatyana Y. Doktorova, Yurika Fujita, Danyel Jennen, Naoki Koyama, Matthew J. Meier, Roman Mezencev, Leslie Recio, Takayoshi Suzuki, Carole L. Yauk   +14 more
wiley   +1 more source

Occupational hazards and bladder cancer-An umbrella review of the risk in workers exposed over the past 30 years. [PDF]

Front Public Health
Mandanach C, Handra CM, Rascu A, Hohor S, Gurzu IL, Otelea MR, Rascu ASC.   +6 more
europepmc   +1 more source

IS CHEMOTHERAPY CARCINOGENIC? [PDF]

CA: A Cancer Journal for Clinicians, 1978
openaire   +3 more sources

Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li, Jiri Aubrecht, Tatyana Y. Doktorova, Danyel Jennen, J. Christopher Corton, Roland Froetschl, Roman Mezencev, Carole L. Yauk   +7 more
wiley   +1 more source

Epigenetic signatures in surrogate tissues are able to assess cancer risk and indicate the efficacy of preventive measures. [PDF]

Commun Med (Lond)
Barrett JE, Herzog CM, Aminzadeh-Gohari S, Redl E, Ishaq Parveen I, Rothärmel J, Tevini J, Weber DD, Catalano L, Stefan VE, Felder TK, Obrist P, Alkasalias T, Gemzell-Danielsson K, Lang R, Kofler B, Widschwendter M.   +16 more
europepmc   +1 more source

Decomposition and Carcinogenic Activity of Azoxyglycosides [PDF]

, 1965
Noel V. Riggs
openalex   +1 more source