Results 241 to 250 of about 94,370 (316)

Global Burden of Hematologic Malignancies From 1990 to 2021 With Projections to 2030: A Systematic Analysis for the Global Burden of Disease Study 2021

iNew Medicine, EarlyView.
ABSTRACT This study aimed to comprehensively analyze the epidemiological trends and global burden of hematologic malignancies (HM) from 1990 to 2021 and to project trends up to the year 2030. Using data from the Global Burden of Disease (GBD) Study 2021, we analyzed the age‐standardized rates (ASRs) and the trends of HM from 1990 to 2021. Decomposition
Ziyuan Shen, Linyu Huang, Xing Xing, Danting Zhang, Guoqi Cai, Wei Sang   +5 more
wiley   +1 more source

Exploring the potential effects of <i>Lactococcus lactis</i> D4 on the proliferation, apoptosis, and inflammatory responses in colorectal cancer cells. [PDF]

Narra J
Rivai MI, Lusikooy RE, Putra AE, Elliyanti A, Sukma A.   +4 more
europepmc   +1 more source

Targeting GRP78 and the Proteostasis Network to Break the Therapeutic Ceiling in Neuroendocrine Prostate Cancer

iNew Medicine, EarlyView.
ABSTRACT HSPA5 (also known as GRP78/BiP) is a master regulator of the endoplasmic reticulum (ER) stress response and a key node in the proteostasis network. In neuroendocrine prostate cancer (NEPC), an aggressive, therapy‐refractory lineage that emerges under pressure from androgen receptor (AR) directed therapies, GRP78 is upregulated and co‐opted to ...
Amos Olalekan Akinyemi, Md Rakibul Alam, Mithu Howlader, Mohammad Esfini Farahani, Lixiang Gu, Chun Li, Chripus Ngule, Kevin Fulp, Bolaji Owoyemi, Xinyi Wang, Samuel Nwadialo, Fatemeh Selani, Makumba Esoe, Obaleye Oluwafunminiyi, Zhiguo Li   +14 more
wiley   +1 more source

Mechanisms and applications of N-Methyl-N'-nitro-N-nitrosoguanidine in animal tumor models: current situation and challenges. [PDF]

Front Oncol
Zhang X, Xu Y, Cao J, Li T, Wang J, Tao J, Zhang L, Li Z.   +7 more
europepmc   +1 more source

Chinese pan‐cancer patient genomic characteristics: A comprehensive analysis based on the National Cancer Center–Clinical Diagnostics Knowledgebase real‐world clinical sequencing cohort

Interdisciplinary Medicine, EarlyView.
We assembled National Cancer Center–Clinical Diagnostics Knowledgebase, a clinical genomic knowledgebase of 6935 tumors with matched normal samples, revealing key somatic alterations and actionable variants (70.2% of the cohort). Enrichment of certain different gene mutations was observed between Chinese and American populations, along with a strong ...
Hongrui Li, Shun Wang, Guowei Zhao, Jiangtao Li, Xin Li, Bingning Wang, Yi Zhang, Mengfei Yao, Lei Guo, Jianming Ying, Wenbin Li   +10 more
wiley   +1 more source

Chemopreventive Effects of Bioactive Peptides Derived from Black Soldier Fly Larvae Protein Hydrolysates in a Rat Model of Early-Stage Colorectal Carcinogenesis. [PDF]

Int J Mol Sci
Praseatsook K, Vachiraarunwong A, Sato K, Dissook S, Wanibuchi H, Taya S, Wongpoomchai R, Dejkriengkraikul P, Gi M, Yodkeeree S.   +9 more
europepmc   +1 more source

Carcinogen [PDF]

, 2019
openaire   +1 more source

Etiome Study Using Molecular Epigenetic Markers and Lung Organoid in Korean School Meal Service Workers (Etiome Study in S-meal Workers): Study Protocol. [PDF]

J Prev Med Public Health
Moon S, Sung S, Park SK.
europepmc   +1 more source

Cancer and Environmental Xenobiotics: Mechanisms, Controversies, and Innovations. [PDF]

J Xenobiot
Mafe AN, Büsselberg D.
europepmc   +1 more source

Occupational hazards and bladder cancer-An umbrella review of the risk in workers exposed over the past 30 years. [PDF]

Front Public Health
Mandanach C, Handra CM, Rascu A, Hohor S, Gurzu IL, Otelea MR, Rascu ASC.   +6 more
europepmc   +1 more source