Results 251 to 260 of about 167,587 (340)

Cross‐Coupling Reactions in Aqueous Micellar Media

European Journal of Organic Chemistry, Accepted Article.
Thanks to their ability to efficiently and reliably construct carbon‐carbon and carbon‐heteroatom bonds, cross‐coupling reactions remain at the forefront of chemical research in both academic and industrial settings. However, the growing emphasis on sustainability has exposed the shortcomings of cross‐coupling chemistry in several areas, including the ...
Alexander Uner, Liam Thomas Ball
wiley   +1 more source

Long-Term Latency of Highly Mutated Cells in Normal Mouse Skin Is Reversed by Exposure to Tumor Promoters and Chronic Tissue Damage. [PDF]

Cancer Discov
Li YR, Kandyba E, Halliwill K, Delrosario R, Tran Q, Bayani N, Wu D, Mirzoeva OK, Reeves MQ, Islam SMA, Riva L, Bergstrom EN, Achanta K, DiGiovanni J, Alexandrov LB, Balmain A.   +15 more
europepmc   +1 more source

Oral, subcutaneous and intratracheal administration of carcinogenic lactones and related substances: the intratracheal administration of cigarette tar in the rat.

, 1966
F. Dickens, Helen Jones, H. B. Waynforth
openalex   +2 more sources

Electrochemical Biosensors for Cancer Biomarker Detection: Basic Concept, Design Strategy and Cutting‐Edge Development

Electrochemical Science Advances, EarlyView.
ABSTRACT Cancer is a result of uncontrolled cell growth with the potential to damage or spread to another part of the body. It is the deadliest disease in the world; therefore, rapid and sensitive detection is essential to fight it. In the past few decades, many diagnosis tools have been developed to detect cancer and monitor therapy progress.
Md Mobarok Karim, Tahera Lasker
wiley   +1 more source

Optimizing Preclinical Models for Oral Cancer: The Influence of 4NQO Administration Routes on Tumor Development. [PDF]

Cancers (Basel)
Van den Bosch J, Caz N, Martens S, Erens C, Rasking L, Gervois P, Nijsten K, Himmelreich U, Van Cauter S, Hillen LM, Plasschaert H, Lambrichts I, Wolfs E.   +12 more
europepmc   +1 more source

Chemically contaminated aquatic food resources and human cancer risk: retrospective [PDF]

, 1991
Dawe, C. J., Farrington, J. W., Fouts, J. R., Harshbarger, J. C., Murchelano, R. A., Ozonoff, D., Pritchard, J. B., Stegeman, J. J.   +7 more
core   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

In reply to: "Letter to the editor in response to the article:'Squamous cell carcinoma arising in chronically damaged skin (Marjolijn's Ulcer)'". [PDF]

Oncologist
Miodovnik M, Dolev Y, Buchen R, Brezis MR, Nikolaevski-Berlin A, Finkel I, Wolf I, Ospovat I, Gutfeld O, Leshem Y.   +9 more
europepmc   +1 more source

Oral Methotrexate in Mice: A Co-Carcinogenic as Well as an Anti-Tumor Agent to Methylcholanthrene-Induced Cutaneous Tumors**From the Clinical Laboratories, Jewish Hospital, Cincinnati and the Departments of Dermatology and Pathology, College of Medicine, University of Cincinnati, Cincinnati 29, Ohio.

, 1962
Louis L. Barich, Jan Schwarz, Donna Barich   +2 more
openalex   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source