Results 261 to 270 of about 164,713 (337)

Diet, Gastric Microbiota, and Metabolites in Gastric Tumorigenesis. [PDF]

Research (Wash D C)
Jiang L, Lau HC, Zeng R, Yu J.
europepmc   +1 more source

Effect of Basic Cupric Acetate on the Biochemical Changes in the Liver of the Rat fed Carcinogenic Aminoazo Dye. I. Changes in the Activities of DAB Metabolism by Liver Homogenate

, 1969
Yasuhiro Yamane, Kazuo Sakai, Isao Uchiyama, MISUE TABATA, NORIKO TAGA, Akira Hanaki   +5 more
openalex   +2 more sources

Evaluation of the standard battery of in vitro genotoxicity tests to predict in vivo genotoxicity through mathematical modeling: A report from the 8th International Workshop on Genotoxicity Testing

Environmental and Molecular Mutagenesis, EarlyView.
Abstract In human health risk assessment of chemicals and pharmaceuticals, identification of genotoxicity hazard usually starts with a standard battery of in vitro genotoxicity tests, which is needed to cover all genotoxicity endpoints. The individual tests included in the battery are not designed to pick up all endpoints.
Mirjam Luijten, Jan van Benthem, Takeshi Morita, Raffaella Corvi, Patricia A. Escobar, Yurika Fujita, Jennifer Hemmerich, Naveed Honarvar, David Kirkland, Naoki Koyama, David P. Lovell, Miriam Mathea, Andrew Williams, Stephen Dertinger, Stefan Pfuhler, Jeroen L. A. Pennings   +15 more
wiley   +1 more source

Pulling EDB-contaminated foods off supermarket shelves: A collegial approach to complex and uncertain science [PDF]

, 2011
Greenberg, Arthur
core   +1 more source

Consensus findings of an International Workshops on Genotoxicity Testing workshop on using transcriptomic biomarkers to predict genotoxicity

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl, J. Christopher Corton, Henghong Li, Jiri Aubrecht, Scott S. Auerbach, Florian Caiment, Tatyana Y. Doktorova, Yurika Fujita, Danyel Jennen, Naoki Koyama, Matthew J. Meier, Roman Mezencev, Leslie Recio, Takayoshi Suzuki, Carole L. Yauk   +14 more
wiley   +1 more source

Saponins in soy reduce NNK-induced lung cancer by increasing plasma isoflavone levels. [PDF]

Sci Rep
Elisia I, Yeung M, Kowalski S, Wong A, Dietrich C, Wu S, Chang V, Adomat H, Krystal G.   +8 more
europepmc   +1 more source

Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li, Jiri Aubrecht, Tatyana Y. Doktorova, Danyel Jennen, J. Christopher Corton, Roland Froetschl, Roman Mezencev, Carole L. Yauk   +7 more
wiley   +1 more source

QM-CSA: A Novel Quantum Mechanics-Based Protocol for Evaluation of the Carcinogen-Scavenging Activity of Polyphenolic Compounds. [PDF]

Foods
Furlan V, Tošović J, Bren U.
europepmc   +1 more source

Effects of carcinogen and cortisone on mast cells in the hamster cheek pouch.

, 1967
C.J. Smith
openalex   +2 more sources

The Humble Almond: Why Congress Should Institute the Precautionary Principle to Guide Regulation of Environmental Toxins and Food Additives [PDF]

, 2015
Nauheim, David Alan
core   +1 more source