Results 21 to 30 of about 94,370 (316)

Analysis of annexin 7 gene of malignant prostatic hyperplasia-induced male wistar rats in the presence of Annona muricata

open access: yesJournal of Taibah University for Science, 2019
Background: Prostate cancer has become the most common cancer among African – American men and the second leading cause of cancer death in men worldwide.
Joseph Bamidele Minari   +1 more
doaj   +1 more source

PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo

open access: yesCells, 2019
In most cancers, cellular origin and the contribution of intrinsic and extrinsic factors toward transformation remain elusive. Cell specific carcinogenesis models are currently unavailable. To investigate cellular origin in carcinogenesis, we developed a
Yu-Ting Yen   +6 more
doaj   +1 more source

The magnetic field near power lines in the Moscow region: the results of measurements and their analyze [PDF]

open access: yesСаратовский научно-медицинский журнал, 2014
The aim: to analyze the real power frequency magnetic field (50 Hz) values near power lines. The material. Long-term measurements of the power frequency magnetic field (50 Hz) near power lines of 110 kV, 220 kVand 500 kVin the Moscow region.
Prokofyeva A.S., Grigoriev O.A.
doaj  

Predicting residential radon concentrations in Finland: Model development, validation, and application to childhood leukemia

open access: yesScandinavian Journal of Work, Environment & Health, 2020
OBJECTIVES: Inhaled radon gas is a known alpha-emitting carcinogen linked especially to lung cancer. Studies on higher concentrations of indoor radon and childhood leukemia have conflicting but largely negative results.
Atte Nikkilä   +6 more
doaj   +1 more source

Mouse Models for Application in Colorectal Cancer: Understanding the Pathogenesis and Relevance to the Human Condition

open access: yesBiomedicines, 2022
Colorectal cancer (CRC) is a malignant disease that is the second most common cancer worldwide. CRC arises from the complex interactions among a variety of genetic and environmental factors. To understand the mechanism of colon tumorigenesis, preclinical
Chuangen Li   +3 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

N-OH-AABP Modifications in Human DNA May Lead to Auto-Antibodies in Bladder Cancer Subjects

open access: yesDiagnostics, 2022
4-Aminobiphenyl (4-ABP) and other related arylamines have emerged to be responsible for human urinary bladder tumors and cancers. Hemoglobin-ABP adducts have been recognized in the blood of smokers, and it builds up in the circulatory system over the ...
Uzma Shahab   +7 more
doaj   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

Say ‘no’ to carcinogen as contraception alternative

open access: yesAfrican Journal of Primary Health Care & Family Medicine, 2012
A response to Correspondence to ‘Dienye PO, Gbeneol PK. Contraception as a risk factor for urinary tract infection in Port Harcourt, Nigeria: A case control study. Afr J Prm Health Care Fam Med. 2011;3(1), Art. #207, 4 pages.
Karen Malec
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

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