Results 41 to 50 of about 238,323 (340)

Cancer incidence in sites potentially related to occupational exposures: 58 years of follow-up of firefighters in the Norwegian Fire Departments Cohort

open access: yesScandinavian Journal of Work, Environment & Health, 2022
OBJECTIVES: Firefighters are exposed to a variety of known and suspected carcinogens through their work. However, the association with cancer risk has limited evidence.
Niki Marjerrison   +7 more
doaj   +1 more source

(S)-N'-Nitrosonornicotine, a constituent of smokeless tobacco, is a powerful oral cavity carcinogen in rats.

open access: yesCarcinogenesis, 2013
Currently, smokeless tobacco products are being proposed as an alternative mode of tobacco use associated with less harm. All of these products contain the tobacco-specific carcinogen N'-nitrosonornicotine (NNN). The major form of NNN in tobacco products
S. Balbo   +10 more
semanticscholar   +1 more source

Carcinogenicity of saccharin. [PDF]

open access: yesEnvironmental Health Perspectives, 1978
Saccharin is carcinogenic for the urinary bladder in rats and mice, and most likely is carcinogenic in human beings. The neoplasms of the urinary bladder are malignant and invade and metastasize. Male rats are more susceptible to urinary bladder carcinogenesis than female rats. Rats exposed as fetuses develop neoplasms more readily than rats exposed as
openaire   +4 more sources

A Canadian First Nations radon assessment and COVID-19 restrictions: A difficult pairing

open access: yesJournal of Community Safety and Well-Being, 2023
Radon is a known carcinogen and a by-product of degrading naturally occurring radioactive elements. The North Shore Micmac District Council (NSMDC) board of directors, in Eastern New Brunswick, Canada, were aware of this issue and saw a need for ...
Jared Bishop
doaj   +1 more source

Contributions of human enzymes in carcinogen metabolism.

open access: yesChemical Research in Toxicology, 2012
Considerable support exists for the roles of metabolism in modulating the carcinogenic properties of chemicals. In particular, many of these compounds are pro-carcinogens that require activation to electrophilic forms to exert genotoxic effects.
Slobodan Petar Rendic, F. Guengerich
semanticscholar   +1 more source

Potential of Animal Excreta as a Source of Probiotic Lactic Acid Bacteria for Aflatoxin B1 Detoxification by the Surface Binding Mechanism

open access: yesJournal of Pure and Applied Microbiology, 2023
Aflatoxins (AFs) are the most potent and ubiquitously found mycotoxins, capable of causing contamination in agricultural products. Aflatoxin B1 (AFB1) is the most toxic and primarily produced Aflatoxin and will be a real threat to the safety of food and ...
Chammakalayil Sukumaran Arun   +3 more
doaj   +1 more source

A Dietary Antioxidant Formulation Ameliorates DNA Damage Caused by γ-Irradiation in Normal Human Bronchial Epithelial Cells In Vitro

open access: yesAntioxidants, 2022
Antioxidants can be used as radioprotectants to reduce DNA damage due to exposure to radiation that could result in malignancies, including lung cancer. Mortality rates are consistently higher in lung cancer, which is usually diagnosed at later stages of
J. P. Jose Merlin   +4 more
doaj   +1 more source

The Carcinogenicity of Beryllium [PDF]

open access: yesEnvironmental Health Perspectives, 1981
Beryllium, some of its alloys, and a variety of its compounds have induced malignant tumors of the lung and osteogenic sarcoma in experimental animals. Three animal species, monkeys, rabbits, and rats, have been shown to be susceptible. Beryllium induces morphological transformation in mammalian cells and enhances viral transformation of mammalian ...
openaire   +3 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

open access: yesMolecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

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