Head and neck squamous cell carcinoma
Head and neck squamous cell carcinomas (HNSCCs) originate from the mucosal epithelium in the oral cavity, pharynx and larynx, and are caused by viral infection or carcinogen exposure.
semanticscholar +1 more source
A priority list of occupational carcinogenic agents for preventative action in Australia
Objective: To develop a list of carcinogens to guide decisions on priorities for preventive action in Australian workplaces. Approach: The following criteria provided the assessment framework to establish a list of priority carcinogens: evidence of ...
Renae C. Fernandez+6 more
doaj +1 more source
PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo
In most cancers, cellular origin and the contribution of intrinsic and extrinsic factors toward transformation remain elusive. Cell specific carcinogenesis models are currently unavailable. To investigate cellular origin in carcinogenesis, we developed a
Yu-Ting Yen+6 more
doaj +1 more source
The Carcinogenicity of Arsenic [PDF]
A carcinogenic role of inorganic arsenic has been suspected for nearly a century. Exposure to inorganic arsenic compounds occurs in some occupational groups, e.g., among smelter workers and workers engaged in the production and use of arsenic containing pesticides. Substantial exposure can also result from drinking water in certain areas and the use of
openaire +3 more sources
Reduction in squamous cell carcinomas in mouse skin by dietary zinc supplementation. [PDF]
Inadequate dietary Zn consumption increases susceptibility to esophageal and other cancers in humans and model organisms. Since Zn supplementation can prevent cancers in rodent squamous cell carcinoma (SCC) models, we were interested in determining if it
Druck, Teresa+9 more
core +2 more sources
Scientific Ignorance and Reliable Patterns of Evidence in Toxic Tort Causation: Is There a Need for Liability Reform? [PDF]
As a first step to preserving the central aims of tort law, courts will need to recognize the wide variety of respectable, reliable patterns of evidence on which scientists themselves rely for drawing inferences about the toxicity of substances.
Cranor, Carl F., Eastmond, David A.
core +2 more sources
N-OH-AABP Modifications in Human DNA May Lead to Auto-Antibodies in Bladder Cancer Subjects
4-Aminobiphenyl (4-ABP) and other related arylamines have emerged to be responsible for human urinary bladder tumors and cancers. Hemoglobin-ABP adducts have been recognized in the blood of smokers, and it builds up in the circulatory system over the ...
Uzma Shahab+7 more
doaj +1 more source
Do topical repellents divert mosquitoes within a community? Health equity implications of topical repellents as a mosquito bite prevention tool. [PDF]
OBJECTIVES: Repellents do not kill mosquitoes--they simply reduce human-vector contact. Thus it is possible that individuals who do not use repellents but dwell close to repellent users experience more bites than otherwise.
DC Chavasse+22 more
core +3 more sources
OBJECTIVES: Inhaled radon gas is a known alpha-emitting carcinogen linked especially to lung cancer. Studies on higher concentrations of indoor radon and childhood leukemia have conflicting but largely negative results.
Atte Nikkilä+6 more
doaj +1 more source
The Carcinogenicity of Beryllium [PDF]
Beryllium, some of its alloys, and a variety of its compounds have induced malignant tumors of the lung and osteogenic sarcoma in experimental animals. Three animal species, monkeys, rabbits, and rats, have been shown to be susceptible. Beryllium induces morphological transformation in mammalian cells and enhances viral transformation of mammalian ...
openaire +3 more sources