Results 171 to 180 of about 534,637 (340)

MUC15 Ectodomain Architecture Regulates Integrin Clustering to Control Cancer Metastasis

Advanced Science, EarlyView.
This study uncovers a size‐dependent adhesion paradigm, demonstrating that the glycocalyx protein MUC15 suppresses pancreatic cancer progression by attenuating integrin activation, focal adhesion assembly, and YAP mechanotransduction. Integrating computational modeling and experimental validation, the work reveals a mechanical mechanism by which MUC15 ...
Simei Zhang, Hongyuan Zhu, Zeen Zhu, Shuai Wu, Yiqun Song, Jin Wang, Xinlong Chen, Weikun Qian, Jianpeng Li, Yangyang Yue, Qinhong Xu, Zhiping Ruan, Qing Li, Yaomin Zhu, Tian Jian Lu, Guy M. Genin, Feng Xu, Zheng Wang, Min Lin   +18 more
wiley   +1 more source

Comprehensive Measurement of Inter‐Individual Variation in DNA Repair Capacity in Healthy Individuals

Advanced Science, EarlyView.
Susceptibility to the health effects of DNA damage depends on a person's ability to repair DNA damage, but DNA repair has been difficult to measure in populations. A functional assay called FM‐HCR is used to measure DNA repair in 6 major pathways across 56 individuals.
Ting Zhai, Patrizia Mazzucato, Catherine Ricciardi, David C. Christiani, Liming Liang, Leona D. Samson, Isaac A. Chaim, Zachary D. Nagel   +7 more
wiley   +1 more source

Electrosensitive Heterogeneous Short Fibers via Acousto‐Electric Coupling for Sequential Bone Regeneration in Infectious Defects

Advanced Science, EarlyView.
Electrosensitive heterogeneous short fibers can accurately respond to ultrasonic field regulation through the synergistic interaction of piezoelectric and conductive dual elements. At an ultrasound intensity of 1.5 W cm−2, it can effectively activate bacterial peroxisome and necrotic apoptotic pathway and promote bacterial apoptosis.
Xiaoyu Han, Fan Wang, Pengcheng Xiao, Zheng Yang, Mingyue Liu, Zeyu Han, Zijie Wang, Anan Jiang, Jindong Tan, Juan Wang, Wenguo Cui, Dingqun Bai   +11 more
wiley   +1 more source

Carcinogénesis

Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica, 1999
El fenómeno de la carcinogénesis debe ser entendido como un proceso de adaptación celular frente a diferentesagresores físicos, químicos o biológicos, que termina en una disregulación de los procesos de división y diferenciación celular.
Adriana García Herrera
doaj  

Experimental Epidermal Methylcholanthrene Carcinogenesis in Mice

, 1945
E. V. Cowdry
openalex   +1 more source

Association Between Cholecystectomy and Gastric Cancer in a Cohort Study in Taiwan

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Objective The association between cholecystectomy and gastric cancer is undetermined. The objective of this study was to assess whether subjects with cholecystectomy are at risk of gastric cancer in Taiwan. Methods This study used data from a cohort of 2 000 000 beneficiaries over a twelve‐year period (2010–2021) from the Taiwan National ...
Kuan‐Fu Liao, Cheng‐Chan Yu, Sheng‐Chun Chiu, Yu‐Hung Kuo, Shih‐Wei Lai   +4 more
wiley   +1 more source

A Further Investigation of the Rôle of Skin Components in Chemical Carcinogenesis

, 1955
June Marchant, J. W. Orr
openalex   +2 more sources

Clinically Informed Intelligent Classification of Ovarian Cancer Cells by Label‐Free Holographic Imaging Flow Cytometry

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Quantitative phase maps of single cells recorded in flow cytometry modality feed a hierarchical architecture of machine learning models for the label‐free identification of subtypes of ovarian cancer. The employment of a priori clinical information improves the classification performance, thus emulating the clinical application of liquid biopsy during ...
Daniele Pirone, Beatrice Cavina, Daniele Gaetano Sirico, Martina Mugnano, Vittorio Bianco, Lisa Miccio, Anna Myriam Perrone, Anna Maria Porcelli, Giuseppe Gasparre, Ivana Kurelac, Pasquale Memmolo, Pietro Ferraro   +11 more
wiley   +1 more source

Elucidating biomarkers of carcinogenesis in ulcerative colitis: insight from Mendelian randomization and transcriptomics. [PDF]

Discov Oncol
Xiao X, Wu X, Liu T, Cai Y.
europepmc   +1 more source

Recent Advancements in Topic Modeling Techniques for Healthcare, Bioinformatics, and Other Potential Applications

Advanced Intelligent Systems, EarlyView.
This article offers a comprehensive review of topic modeling techniques, tracing their evolution from inception to recent developments. It explores methods such as latent Dirichlet allocation, latent semantic analysis, non‐negative matrix factorization, probabilistic latent semantic analysis, Top2Vec, and BERTopic, highlighting their strengths ...
Pratima Kumari, Sachin Kadian, Mukund Vora, Pradyumna Vemuri, Sumit Kumar, Om Prakash Verma, Roger J. Narayan   +6 more
wiley   +1 more source