Results 161 to 170 of about 327,951 (318)

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Hereditary chronic pancreatitis induced plasticity cooperates with mutant Kras in early pancreatic carcinogenesis. [PDF]

Gut
Inamdar TV, Krannich F, Hesselbarth N, Verma A, Vauti T, Jasaszwili MH, El Kassem G, Hillmer J, Kaune T, Boettcher M, Regel I, Griesmann H, Esposito I, Glaß M, Hämmerle M, Michl P, Laumen H, Rosendahl J.   +17 more
europepmc   +1 more source

At what age should people with obesity start colorectal cancer screening?

International Journal of Cancer, EarlyView.
What's New? Early‐onset colorectal cancer (CRC) incidence is rising in the United States, Canada, and parts of Europe, even as rates in older adults stabilize or decline. Excess body weight, which is a known CRC risk factor, is a potential contributor to this trend.
Teresa Seum, Marko Mandic, Fatemeh Safizadeh, Michael Hoffmeister, Hermann Brenner   +4 more
wiley   +1 more source

Correction: Th9 cells at the intersection of IBD and colorectal cancer: a context-dependent factor in carcinogenesis. [PDF]

Inflamm Regen
Afrough N, Soltani A, Khosravi M, Yadolahi N, Khodadadi A, Shohan M.   +5 more
europepmc   +1 more source

Cardiovascular disease incidence and cancer risk in two large European prospective cohorts

International Journal of Cancer, EarlyView.
What's New? Cardiovascular disease (CVD) and cancer share risk factors and biological mechanisms, raising questions about potential associations between the two, particularly regarding CVD duration and cancer onset. Whether CVD influences subsequent cancer risk, however, remains inconclusive.
Emma Fontvieille, Vivian Viallon, Laia Peruchet‐Noray, Quan Gan, N. Charlotte Onland‐Moret, Yvonne Koop, Anne Tjønneland, Nicola Patricia Bondonno, Verena Katzke, Rudolf Kaaks, Matthias B. Schulze, Catarina Schiborn, Calogero Saieva, Vittorio Simeon, Claudia Agnoli, Rosario Tumino, Fulvio Ricceri, Leila Luján‐Barroso, Maria‐José Sánchez, Conchi Moreno‐Iribas, Konstantinos K. Tsilidis, Marc J. Gunter, Adam Butterworth, Elio Riboli, Heinz Freisling, Pietro Ferrari   +25 more
wiley   +1 more source

Globo‐H diagnostic stratification and identification of DUSP14 as a candidate target in colorectal cancer

International Journal of Cancer, EarlyView.
What's New? Colorectal cancer (CRC) is increasingly complicated by drug‐resistant tumors that limit the effectiveness of anticancer therapies. Because resistance mechanisms vary among patients and can evolve over time, personalized treatment strategies are needed.
Keren Zohar, Marco Strecker, Thomas Wartmann, Wenjie Shi, Frederike Stelter, Maximilian Doelling, Mihailo Andric, Or Kakhlon, Christian Täger, Denny Schanze, Michael Linnebacher, Michael Naumann, Daniel E. Stange, Dörthe Jechorek, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Two target cells for HPV infection at the cervix? [PDF]

Virus Res
Reich O, Regauer S.
europepmc   +1 more source

Sensitive Period Analysis of Adulthood BMI and Cancer Risk: An Individual Participant Data Meta‐Analysis of Over 720,000 Participants in the ABACus 2 Consortium

International Journal of Cancer, EarlyView.
Over a dozen cancers have been associated with excess body mass index, primarily in mid‐to‐late adulthood. Whether obesity‐related cancer risk differs across adulthood remains unclear. Using the Sensitive Periods Model and super‐landmarking approaches, this study found that higher BMI increased obesity‐related cancer risk across ages 30–65.
Nadin K. Hawwash, Matthew Sperrin, Glen P. Martin, Rashmi Sinha, Charles E. Matthews, Matthias B. Schulze, Anouk Hiensch, Pilar Amiano, Marian L. Neuhouser, Corinne E. Joshu, Elizabeth A. Platz, Heinz Freisling, Marc J. Gunter, Andrew G. Renehan   +13 more
wiley   +1 more source

Enhanced mRNA Expression of Colonic IL-6 in Cronkhite-Canada Syndrome Bearing Colorectal Cancer. [PDF]

In Vivo
Fujihara D, Honjo H, Masuta Y, Otsuka Y, Masaki S, Minaga K, Kamata K, Tsuji N, Watanabe T, Kudo M.   +9 more
europepmc   +1 more source

Meat Intake and Risk of Gastric and Esophageal Adenocarcinoma in the European Prospective Investigation Into Cancer and Nutrition (EPIC) Study

International Journal of Cancer, EarlyView.
Limited evidence links processed meat intake and non‐cardia gastric cancer, while esophageal adenocarcinoma is increasing in Western countries, where diets are typically high in red and processed meats. Using data from over 450,000 participants from a large prospective study, the authors examined meat consumption and the risk of gastric and esophageal ...
Catalina Bonet, Lucía Rizzolo‐Brime, Sara Montañés, Mariem Hajji, Chloé Marques, Gianluca Severi, Matthias B Schulze, Christina C. Dahm, Anne Tjønneland, Anja Olsen, Maria S. De Magistris, Valeria Pala, Alberto Catalano, Guri Skeie, Magritt Brustad, Torill Enget Jensen, Maria‐José Sánchez, Marcela Guevara, Natalia Cabrera Castro, Keren Papier, Elisabete Weiderpass, Viktoria Knaze, Jin Young Park, Gwen Murphy, Antonio Agudo, Paula Jakszyn   +25 more
wiley   +1 more source