Results 141 to 150 of about 281,280 (268)

Is Exposure to Certain Endocrine-Disrupting Chemicals Associated with Increased Skin Cancer Risk? [PDF]

Cancers (Basel)
Betsi G, Koumaki D, Kountouri A, Xekouki P.   +3 more
europepmc   +1 more source

Epigenetic Predictors of Smoking: External Validation and Association With Smoking‐Related Cancer Risk

International Journal of Cancer, EarlyView.
ABSTRACT Tobacco smoking has a strong influence on DNA methylation (DNAm), enabling the development of DNAm‐based smoking predictors, yet external evaluations of these have remained limited. We aimed to assess six DNAm‐based smoking predictors in a large sample of middle‐aged and older Australians for (i) their accuracy and reliability, and (ii) their ...
Xiaoyu Fan, Danmeng Lily Li, Allison M. Hodge, Julie K. Bassett, Nina Afshar, Melissa C. Southey, Graham G. Giles, Roger L. Milne, Pierre‐Antoine Dugué   +8 more
wiley   +1 more source

Correction: Multi‑omics analysis identifies different molecular subtypes with unique outcomes in early-stage poorly differentiated lung adenocarcinoma. [PDF]

Mol Cancer
Liu B, Tao W, Zhou X, Xu LD, Luo Y, Yang X, Min Q, Huang M, Zhu Y, Cui X, Wang Y, Gong T, Zhang E, Huang YS, Chen W, Yan S, Wu N.   +16 more
europepmc   +1 more source

Human Protein Biomarkers Outperform Bacterial Proteins in Colorectal Cancer Detection

International Journal of Cancer, EarlyView.
ABSTRACT Colorectal cancer (CRC) generally develops from precancerous adenomatous lesions, including advanced adenomas (AA), through a sequence of carcinogenic molecular alterations. The composition of the gut microbiota and the fecal proteome is known to differ between individuals with AA and CRC compared to controls, providing opportunities for ...
Roza C. M. Opperman, Sofie Bosch, Alex A. Henneman, Thang V. Pham, Sander R. Piersma, Tim G. J. de Meij, Meike de Wit, Beatriz Carvalho, Remond J. A. Fijneman, Gerrit A. Meijer, Evelien Dekker, Connie R. Jimenez, Nanne K. H. de Boer   +12 more
wiley   +1 more source

Periodontitis as a Modulator of Malignant Transformation in Oral Potentially Malignant Disorders: A Narrative Review of Biological Mechanisms and Clinical Implications. [PDF]

Curr Oncol Rep
Pieretto G, Sansavini M, Cortes ARG, Bacci C.   +3 more
europepmc   +1 more source

Oral and Fecal Microbial Dysbiosis as Non‐Invasive Diagnostic Biomarkers for Gastrointestinal Cancers: A Systematic Review and Meta‐Analysis of Diagnostic Accuracy

International Journal of Cancer, EarlyView.
ABSTRACT Gastrointestinal (GI) cancers, including esophageal (EC), gastric (GC), and colorectal cancer (CRC), impose a substantial global burden, with early detection remaining crucial for improving patient outcomes. The oral and gut microbiota are increasingly implicated in cancer development and hold promise as sources of non‐invasive biomarkers ...
Saidi Hu, Zhouyan Chen, Yanxia Li, Qingyan Liao, Mingdong Luo, Danyang Song, Hanyue Yu, Yuetong Gao, Shuanglong Yang, Siran Wan, Shunhong Zhang, Chenchen Luo, Lin‐Yong Zhao   +12 more
wiley   +1 more source

Tobacco-associated carcinogenesis with nicotine-mediated tumor promotion across the gastrointestinal tract: A narrative review. [PDF]

Tob Prev Cessat
Padmanabhan S, Khan-Garrard M, Gupta B, Carnevale KA.   +3 more
europepmc   +1 more source

Comparison of HPV Antibodies Measured Prior to Diagnosis of Anal, Cervical, Oropharyngeal, Penile and Vaginal Cancers in the HPV Cancer Cohort Consortium

International Journal of Cancer, EarlyView.
ABSTRACT Antibodies against HPV proteins can provide pre‐diagnostic information about cancer development. We described the prevalence of antibodies to proteins of oncogenic HPV types prior to diagnosis of HPV‐related cancers. We analysed pre‐diagnostic blood from 1700 participants with incident HPV‐related cancers (anal = 387, cervical = 274 ...
Justina Ucheojor Onwuka, Marie‐Pierre Nobels, Aimée R. Kreimer, Lea Schroeder, Aida Ferreiro‐Iglesias, Ilir Agalliu, Demetrius Albanes, Qiuyin Cai, Gypsyamber D'Souza, Neal D. Freedman, Graham G. Giles, Allan Hildesheim, Wen‐Yi Huang, Kristian Hveem, Hilde Langseth, Roger L. Milne, Eivind Ness‐Jensen, Nicolas F. Schlecht, Lesley F. Tinker, Giske Ursin, Kala Visvanathan, Sylvia Wassertheil‐Smoller, Stephanie J. Weinstein, Wei Zheng, Mari Nygard, Mattias Johansson, Tim Waterboer, Gary M. Clifford, Hilary A. Robbins   +28 more
wiley   +1 more source

Gastric bacterial microbiota and gastric carcinogenesis: from dysbiosis to immune remodeling and therapeutic opportunities. [PDF]

Front Immunol
Huang S, Cheng Y, Chen Y, Liu Y, Liu X, Xu X, Hu P, Wu L, Ling Z, Xu L.   +9 more
europepmc   +1 more source

The Epithelial Epigenome: A Unified Platform for Cancer Risk Prediction and Prevention Monitoring

International Journal of Cancer, EarlyView.
ABSTRACT Intrinsic biological processes and carcinogenic exposures leave cumulative DNA methylation (DNAme) imprints in epithelial cells. These changes reflect cellular composition, replicative/mitotic age and impaired differentiation capacity, and arise long before clinically detectable cancer, consistent with the concept of field cancerisation ...
Martin Widschwendter
wiley   +1 more source