Results 181 to 190 of about 650,641 (407)

FIB‐3 index as a novel age‐independent predictor of liver fibrosis and prognosis in hepatocellular carcinoma patients undergoing hepatectomy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Fibrosis‐3 index (FIB‐3) can stratify the risk of the survival and the recurrence‐free survival. The FIB‐3 index is a reliable, age‐independent tool for assessing liver fibrosis and prognosis in HCC patients post‐hepatectomy. Its use may improve clinical outcomes and support personalized treatment strategies. Abstract Background Liver fibrosis is a key
Yuki Imaoka   +13 more
wiley   +1 more source

Circular RNA circBbs9 promotes PM2.5-induced lung inflammation in mice via NLRP3 inflammasome activation

open access: yesEnvironment International, 2020
Fine particulate matter (PM2.5) is one of the most important components of environmental pollutants, and is associated with pulmonary injury. However, the biological mechanisms of pulmonary damage caused by PM2.5 are poorly defined, especially the ...
Meizhen Li   +12 more
doaj  

Hypermutability in Carcinogenesis

open access: yesGenetics, 1998
AbstractThe presence of numerous chromosomal changes and point mutations in tumors is well established. At least some of these changes play a role in the development of the tumors. It has been suggested that the number of these genetic changes requires that tumorigenesis involves an increase in mutation rate.
openaire   +3 more sources

Comprehensive genetic analysis of poorly differentiated gastric cancer in young females

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Although the involvement of female sex hormones in the development of poorly differentiated gastric cancer in young females is controversial, our detailed analysis using RNA‐seq suggested that the female sex hormone, β‐estradiol plays a role in the development of poorly differentiated gastric cancer in young females. Abstract Aim The reasons behind the
Nobuhiro Nakazawa   +9 more
wiley   +1 more source

Circ_0025373 inhibits carbon black nanoparticles-induced malignant transformation of human bronchial epithelial cells by affecting DNA damage through binding to MSH2

open access: yesEnvironment International
Carbon black nanoparticles (CBNPs) have been demonstrated to induce DNA damage in epithelial cells. However, the potential of the damage to initiate carcinogenesis and the underlying mechanism remain poorly understood.
Han Zhang   +12 more
doaj  

Surgical and Oncological Outcomes of Conversion Surgery After Hepatic Arterial Infusion Chemotherapy for Initially Unresectable Locally Advanced Hepatocellular Carcinoma

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Conversion surgery for HCC. ABSTRACT Background Since 2013, we have performed conversion surgery after hepatic arterial infusion chemotherapy (HAIC) for initially unresectable locally advanced hepatocellular carcinoma (LA‐HCC). Methods Between 2013 and 2021, we assessed the surgical and oncological outcomes and pathological findings of patients with LA‐
Yuichi Goto   +9 more
wiley   +1 more source

Bile acid–microbiota crosstalk in gastrointestinal inflammation and carcinogenesis

open access: yesNature reviews: Gastroenterology & hepatology, 2018
Wei Jia, G. Xie, Weiping Jia
semanticscholar   +1 more source

Development and Application of Organic Sonosensitizers in Cancer Therapy

open access: yesAggregate, EarlyView.
This review provides a comprehensive overview of organic sonosensitizers employed in cancer treatment, describing their underlying mechanisms and structure‐activity relationship in terms of sonodynamic therapy. The significance of nanotechnology and combination therapy with other oncological modalities (photothermal therapy, photodynamic therapy, etc.)
Yuhan Ding   +5 more
wiley   +1 more source

Radiation carcinogenesis at low doses [PDF]

open access: yes, 1978
Booz, J.   +2 more
core   +1 more source

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