The key regulator circPDE3B promotes arsenic-induced bladder carcinogenesis by affecting STAT3 and NF-κB stability. [PDF]
Gao Y+12 more
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Author Correction: Correlation between positron annihilation lifetime and photoluminescence measurements for calcined Hydroxyapatite. [PDF]
Atta H+4 more
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Hepatitis B virus promotes liver cancer by modulating the immune response to environmental carcinogens. [PDF]
Huang M+11 more
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Salivaomic Biomarkers-An Innovative Approach to the Diagnosis, Treatment, and Prognosis of Oral Cancer. [PDF]
Starska-Kowarska K.
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S- and R-Carvedilol Prevent Benzo(a)pyrene-Induced Lung Carcinogenesis. [PDF]
Shahid A, Yeung S, Andresen BT, Huang Y.
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Future Perspectives and Conclusions from Animal Models of CHI3L1-Related Inflammation-Associated Cancer. [PDF]
Mizoguchi E, Wang S.
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Long-term treatment with benzodiazepines and related Z-drugs exacerbates breast cancer: clinical evidence and molecular mechanisms. [PDF]
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Understanding the impact of mitochondrial DNA mutations on aging and carcinogenesis (Review). [PDF]
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Carcinogenesis is the process that determines the evolution of cancer and it is triggered from mutations in the DNA of normal cells. The resulting alterations in the equilibrium between proliferation and programmed cell death leads to uncontrolled cell division and, therefore, tumor formation.
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An examination has been made of the major chemicals which are known to be carcinogenic, either in animals or in humans. As a result, a generalized type of chemical property seems to be a prerequisite for the carcinogenic activity. In most cases, this is some kind of reactive electrophilic intermediate produced directly from the carcinogen or from one ...
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