Results 271 to 280 of about 285,650 (298)
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Cytogenetic and Genome Research, 2007
MicroRNAs are an abundant class of noncoding RNAs, typically 20–23 nucleotides in length that are often evolutionarily conserved in metazoans and expressed in a cell and tissue specific manner. MicroRNAs exert their gene regulatory activity primarily by imperfectly base pairing to the 3′ UTR of their target mRNAs, leading to mRNA degradation or ...
Carlo M. Croce, John P. Hagan
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MicroRNAs are an abundant class of noncoding RNAs, typically 20–23 nucleotides in length that are often evolutionarily conserved in metazoans and expressed in a cell and tissue specific manner. MicroRNAs exert their gene regulatory activity primarily by imperfectly base pairing to the 3′ UTR of their target mRNAs, leading to mRNA degradation or ...
Carlo M. Croce, John P. Hagan
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Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2004
Traditional views of nutritional carcinogenesis depend on the identification of exogenous carcinogens as major risk factors. As our understanding evolves, it is clear that the pattern of events involves not only exogenous carcinogens, but also metabolic processes and endogenous and exogenous anticarcinogens.
Andrew Collins, Lynnette R. Ferguson
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Traditional views of nutritional carcinogenesis depend on the identification of exogenous carcinogens as major risk factors. As our understanding evolves, it is clear that the pattern of events involves not only exogenous carcinogens, but also metabolic processes and endogenous and exogenous anticarcinogens.
Andrew Collins, Lynnette R. Ferguson
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Nutrition and Cancer, 2003
The dietary status of niacin (vitamin B3) has the potential to influence DNA repair, genomic stability, and the immune system, eventually having an impact on cancer risk, as well as the side effects of chemotherapy in the cancer patient. In addition to its well-known redox functions in energy metabolism, niacin, in the form of NAD, participates in a ...
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The dietary status of niacin (vitamin B3) has the potential to influence DNA repair, genomic stability, and the immune system, eventually having an impact on cancer risk, as well as the side effects of chemotherapy in the cancer patient. In addition to its well-known redox functions in energy metabolism, niacin, in the form of NAD, participates in a ...
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Cancer, 1993
It generally is accepted that approximately 80% of all cancers have an environmental component. However, although the cause and nature of certain human cancers are known, definitive preventative guidelines cannot be offered for many tumors attributed to life style, especially those of the digestive and genitourinary system. This has led to considerable
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It generally is accepted that approximately 80% of all cancers have an environmental component. However, although the cause and nature of certain human cancers are known, definitive preventative guidelines cannot be offered for many tumors attributed to life style, especially those of the digestive and genitourinary system. This has led to considerable
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2010
This chapter gives an overview of occupational causes of cancer and the approaches used to investigate this issue. The controversies and challenges are discussed together with some of the emerging scientific methodologies.
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This chapter gives an overview of occupational causes of cancer and the approaches used to investigate this issue. The controversies and challenges are discussed together with some of the emerging scientific methodologies.
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