Results 371 to 380 of about 650,641 (407)
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Cytogenetic and Genome Research, 2007
MicroRNAs are an abundant class of noncoding RNAs, typically 20–23 nucleotides in length that are often evolutionarily conserved in metazoans and expressed in a cell and tissue specific manner. MicroRNAs exert their gene regulatory activity primarily by imperfectly base pairing to the 3′ UTR of their target mRNAs, leading to mRNA degradation or ...
Carlo M. Croce, John P. Hagan
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MicroRNAs are an abundant class of noncoding RNAs, typically 20–23 nucleotides in length that are often evolutionarily conserved in metazoans and expressed in a cell and tissue specific manner. MicroRNAs exert their gene regulatory activity primarily by imperfectly base pairing to the 3′ UTR of their target mRNAs, leading to mRNA degradation or ...
Carlo M. Croce, John P. Hagan
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The role of oxidative stress in carcinogenesis.
Annual Review of Pharmacology and Toxicology, 2004Chemical carcinogenesis follows a multistep process involving both mutation and increased cell proliferation. Oxidative stress can occur through overproduction of reactive oxygen and nitrogen species through either endogenous or exogenous insults ...
J. Klaunig, L. Kamendulis
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Annals of Internal Medicine, 1969
Abstract This article reviews the role of viruses in cancer. Oncogenic viruses may contain either ribonucleic acid (RNA) or deoxyribonucleic acid (DNA).
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Abstract This article reviews the role of viruses in cancer. Oncogenic viruses may contain either ribonucleic acid (RNA) or deoxyribonucleic acid (DNA).
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Transplacental carcinogenesis by stilbestrol.
New England Journal of Medicine, 1971This editorial argues the cause-and-effect relationship between in utero exposure to diethylstilbestrol (DES) and incidence of vaginal adenocarcinoma among young women.
J. Folkman
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Pathology - Research and Practice, 1996
The activation of p21ras proteins is required in signal transduction pathways that lead to cell proliferation. More recently, a role for p21ras proteins has also been suggested in pathways to apoptosis and in the regulation of the cell cycle. Pointmutated p21ras oncogenes code for constitutively activated p21ras proteins, which disturb the balance ...
F. T. Bosman +2 more
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The activation of p21ras proteins is required in signal transduction pathways that lead to cell proliferation. More recently, a role for p21ras proteins has also been suggested in pathways to apoptosis and in the regulation of the cell cycle. Pointmutated p21ras oncogenes code for constitutively activated p21ras proteins, which disturb the balance ...
F. T. Bosman +2 more
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Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2004
Traditional views of nutritional carcinogenesis depend on the identification of exogenous carcinogens as major risk factors. As our understanding evolves, it is clear that the pattern of events involves not only exogenous carcinogens, but also metabolic processes and endogenous and exogenous anticarcinogens.
Andrew Collins, Lynnette R. Ferguson
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Traditional views of nutritional carcinogenesis depend on the identification of exogenous carcinogens as major risk factors. As our understanding evolves, it is clear that the pattern of events involves not only exogenous carcinogens, but also metabolic processes and endogenous and exogenous anticarcinogens.
Andrew Collins, Lynnette R. Ferguson
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Nutrition and Cancer, 2003
The dietary status of niacin (vitamin B3) has the potential to influence DNA repair, genomic stability, and the immune system, eventually having an impact on cancer risk, as well as the side effects of chemotherapy in the cancer patient. In addition to its well-known redox functions in energy metabolism, niacin, in the form of NAD, participates in a ...
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The dietary status of niacin (vitamin B3) has the potential to influence DNA repair, genomic stability, and the immune system, eventually having an impact on cancer risk, as well as the side effects of chemotherapy in the cancer patient. In addition to its well-known redox functions in energy metabolism, niacin, in the form of NAD, participates in a ...
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TRIM Family Proteins: Roles in Autophagy, Immunity, and Carcinogenesis.
TIBS -Trends in Biochemical Sciences. Regular ed, 2017S. Hatakeyama
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