Results 21 to 30 of about 145,754 (266)
Are there thresholds for carcinogens carcinogenicity?
魚や肉などの焼けこげに含まれている2-amino-3,8-dimethylimidazo[4,5-f ] quinoxaline(MeIQx)のラット肝臓における低用量発がん性を中期発がん性試験法で検討した.その結果,MeIQx?DNA 付加体形成は微量からみられ,より高い用量で8-hydroxy-2′-deoxyquanosine 形成,lacI 遺伝子変異,イニシエーション活性等が誘発された.また,肝臓の前腫瘍性病変であるglutahione S-transferase placental(GST-P)陽性細胞巣は,さらにより高い用量で誘発された.N- ニトロソ化合物であるN-nitrosodiethylamine やN-nitrosodimethylamine でもGST-P ...
FUKUSHIMA, Shoji +3 more
openaire +2 more sources
Polycyclic aromatic hydrocabons (PAHs) and their nitroderivatives (NPAHs) are ubiquitous in the environment and they are produced in several industrial and combustion processes.
Annibal D. Pereira Netto +6 more
doaj +1 more source
Histopathological evaluation of Senecio rhizomatus Rusby in 7,12-dimethylbenz(α) anthracene-induced breast cancer in female rats [PDF]
Background and Aim: Senecio rhizomatus Rusby (SrR) is a medicinal plant of the Asteraceae family and traditionally consumed as infusion in the Andean region from Peru for inflammatory disorders. This study aimed to determine the histopathological changes
Jorge Luis Arroyo-Acevedo +5 more
doaj +1 more source
Fish is an important source of protein in human meals around the world. However, the fish that we are eating may be contaminated with toxicants such as metals and metalloids (MMs), which may pose health risks to consumers.
Delia B. Senoro +5 more
doaj +1 more source
Micronucleus Assay: An Early Diagnostic Tool to Assess Genotoxic Changes in Patients with Tobacco Use, Oral Leukoplakia and Oral Submucous Fibrosis [PDF]
Introduction: Micronuclei (MNi) are acentric chromatid or chromosome fragments produced via genetic damage through genotoxic agents contained in tobacco and betel nut.
Moulshree Kohli +4 more
doaj +1 more source
The concern for firefighters’ occupational exposure to harmful contaminants is growing due to the increase in health issues in the firefighting community.
Arjunsing Girase +2 more
doaj +1 more source
Sodium Nitrite Effects on Some Blood and Biochemical Parameters in Glutathione Treated Male Rats [PDF]
In industrial food production, food preservatives like sodium nitrite are used more frequently. The use of some food preservatives has been linked to teratogenic and carcinogenic effects.
Huda Khassaf
doaj +1 more source
Mycotoxins are metabolites of molds considered to be a major risk factor affecting human and animal health. It is estimated that 25% of the world’s crop production is contaminated with mycotoxins. Mold contamination occurs extensively in fields and is particularly severe in tropical countries.
Peraica, Maja, Domijan, Ana-Marija
openaire +2 more sources
Carcinogenic and anticancer activities of microbiota-derived secondary bile acids
Secondary bile acids (SBAs), which are metabolites produced by gut microbiota, have been implicated in both carcinogenic and anticancer processes. This review explores the dual role of SBAs, focusing on their molecular mechanisms and biological effects ...
Mobina Kouhzad +7 more
doaj +1 more source
ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita +5 more
wiley +1 more source

