Molecular mechanisms of inhalable iron-containing particles driving lung carcinogenesis through the <i>LCN2</i> signaling axis revealed by transcriptomic analysis. [PDF]
Wang L +8 more
europepmc +1 more source
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve +6 more
wiley +1 more source
An integrated study combining network toxicology machine learning and molecular simulation reveals the molecular mechanisms of permanent hair dyes in breast cancer. [PDF]
Yang X +6 more
europepmc +1 more source
Ashwagandha: Is It Safe? Part 1: A Regulatory Review
ABSTRACT Over the last decade, ashwagandha (Withania somnifera (L.) Dunal, AS) has been brought under increasing scrutiny by EU regulators regarding its safety for the use in food supplements, culminating in a recent recommendation for an Article 8 procedure according to Regulation (EC) No. 1925/2006 in the European Union (EU).
T. Brendler +5 more
wiley +1 more source
The Gut-Adipose-Tumor Axis in Obesity-Related Cancer. [PDF]
Feng J +8 more
europepmc +1 more source
The Role of Polyphenols in Respiratory and Gut Health: From the Perspective of Gut‐Lung Axis
ABSTRACT The gut‐lung axis constitutes a dynamic, multidirectional communication platform between the gastrointestinal and respiratory tracts. Its complexity arises from the integrated crosstalk among the microbiota, immune system, and redox homeostasis, collectively influencing disease susceptibility and progression.
Jian Kang +7 more
wiley +1 more source
Occupational exposure to heavy metals: A review of health outcomes and safety interventions. [PDF]
Chaudhary MD +7 more
europepmc +1 more source
Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death
ABSTRACT Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron‐dependent form of regulated non‐apoptotic cell death driven by lipid peroxidation.
Valentina Citi +6 more
wiley +1 more source
Molecular and microenvironmental drivers of malignant transformation from oral potentially malignant disorders to oral squamous cell carcinoma. [PDF]
V V, R S, S S, R M.
europepmc +1 more source
This review summarizes the recent progress in responsive NO‐releasing materials and their applications in biofilm‐associated infectious diseases. The design principles and response mechanisms are given to provide inspiration toward the future development of multi‐responsive NO‐releasing materials.
Wenyue Sun +8 more
wiley +1 more source

