Results 211 to 220 of about 37,457 (237)

Studies on chemical carcinogens and mutagens. XXIX. Mutagenic N-trimethylsilylmethyl-N-nitrosourea as a biological alkylating agent equivalent to N-methyl-N-nitrosourea (MNU).

Mutation research, 1985
N-Trimethylsilylmethyl-N-nitrosourea (TMS-MNU), a silicon analogue of N-neopentyl-N-nitrosourea (neoPNU), was assayed for mutagenicity and/or cytotoxicity on a series of E. coli B tester strains, S. typhimurium TA100, Chinese hamster V79, and cultured murine leukemia L1210 cells. All the biological activities demonstrated in this study reveal that this
A, Hakura, K, Kohda, Y, Kawazoe
openaire   +2 more sources

Precision Medicine in Metastatic Colorectal Cancer: Relevant Carcinogenic Pathways and Targets-PART 2: Approaches Beyond First-Line Therapy, and Novel Biologic Agents Under Investigation.

Oncology (Williston Park, N.Y.), 2018
A frequent quandary for oncologists is the selection of chemotherapy and biologic therapy for patients with metastatic colorectal cancer in second-line and higher treatment settings. While not approved by the US Food and Drug Administration (FDA) in the first-line setting, the vascular endothelial growth factor (VEGF)-targeting agents ziv-aflibercept ...
Benjamin A, Weinberg, Marion L, Hartley, Mohamed E, Salem   +2 more
openaire   +1 more source

o-Methoxy Derivatives of the Carcinogen, N-2-Fluorenylacetamide. Potential Latent Biological Arylating Agents¹

Journal of Medicinal Chemistry, 1966
H. T. Nagasawa, H. R. Gutmann
openaire   +1 more source

Enzyme-biological Synthesis of a Carcinogenic Agent (Cancervirus) Starting from Nucleotides

Pathologia et Microbiologia, 2010
openaire   +1 more source

Carcinogenicity of some biological agents.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1995
H, Moeller, P, Correa
openaire   +1 more source

The contribution of experimental studies to risk assessment of carcinogenic agents in humans

Experimental Pathology, 1990
L Tomatis
exaly  

Nucleophilic selectivity as a determinant of carcinogenic potency (TD50) in rodents: a comparison of mono- and bi-functional alkylating agents and vinyl chloride metabolites

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1989
A Barbin, Alain Barbin, Helmut Bartsch   +2 more
exaly  

Enzyme-Biological Synthesis of a Carcinogenic Agent (“Cancervirus”) Starting from Nucleotides. III. Biophysico-Chemical Studies with Cancerigenic DNA and Synthesis of a Cancerigenic DNA Containing Antimetabolites of the Purine and Pyrimidinc Bases

Pathologia et Microbiologia, 2010
openaire   +1 more source

Omicron-methoxy derivatives of the carcinogen, N-2-fluorenylacetamide. Potential latent biological arylating agents.

Journal of medicinal chemistry, 1967
H T, Nagasawa, H R, Gutmann
openaire   +1 more source

Multi-endpoint biological monitoring in combined, carcinogenic occupational exposures

International Journal of Environmental Health Research, 2017
Csaba Varga, Katalin Szendi
exaly