Results 201 to 210 of about 113,709 (339)

Recent Developments in the Field of Air‐Stable Nickel(0) Precatalysts for Cross‐Coupling Reactions

European Journal of Inorganic Chemistry, EarlyView.
The development of bench‐stable Ni(0) sources aims to replace air‐sensitive [Ni(COD)2] (cod = cycloocta‐1,5‐diene) with easy‐to‐handle alternatives. Through a targeted ligand design, using electron‐deficient dienes, carbenes, and fluorophosphines, researchers have achieved air‐ and moisture‐tolerant complexes that show high catalytic activity in cross ...
Franziska Flecken, Schirin Hanf
wiley   +1 more source

Enhancing multi-task in vivo toxicity prediction via integrated knowledge transfer of chemical knowledge and in vitro toxicity information. [PDF]

J Cheminform
Park M, Shin Y, Kim H, Nam H.
europepmc   +1 more source

Comparative analysis on isotherm and kinetic modelling for the adsorption of carcinogenic pollutants onto modified graphite intercalation compounds

Faisal Raza, Tausif Ahmad, Hafiz Muhammad Anwaar Asghar, Muhammad Irfan, Hafiz Abdul Mannan, Aqeel Afzal, Zaeem Bin Babar   +6 more
openalex   +2 more sources

Sustainability in Analytical Chemistry Illustrated by Pharmaceutical Nitrosamine Testing

ELECTROPHORESIS, EarlyView.
ABSTRACT Following the valsartan scandal in 2018, the testing of drug substances and drug products for N‐nitrosamines has become a critical and mandatory quality control measure. The European Pharmacopoeia chapter 2.5.42 currently describes three analytical methods for this purpose: HPLC–MS/MS, GC–MS, and GC–MS/MS.
Felix Bredendiek, Sebastian Schmidtsdorff, Maria Kristina Parr   +2 more
wiley   +1 more source

<i>In</i> silico toxicological risk assessment of chemical constituents from <i>Curtisia dentata</i> stem-bark extract. [PDF]

Toxicol Rep
van Wyk AS, Ojo O, Bodede O, Prinsloo G.
europepmc   +1 more source

Carcinogenicity studies

Folia Pharmacologica Japonica, 2007
openaire   +3 more sources

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Comparative Carcinogenicity of Double-Walled Carbon Nanotubes of Different Lengths Administered by Intratracheal Installation into Rat Lungs. [PDF]

Nanomaterials (Basel)
Ahmed OHM, Saleh DM, Alexander WT, Takase H, Taquahashi Y, Hojo M, Maeno A, Fukamachi K, Gi M, Hirose A, Tsuruoka S, Takahashi S, Tsuda H, Naiki-Ito A.   +13 more
europepmc   +1 more source

Perinatal and Multigenerational Effect of Carcinogens: Possible Contribution to Determination of Cancer Susceptibility

, 1992
Hiroshi Yamasaki, Alexandre Loktionov, Lorenzo Tomatis   +2 more
openalex   +2 more sources

Carcinogen-induced impairment of enzymes for replicative fidelity of DNA and the initiation of tumours [PDF]

, 2003
Leon P. Bignold
openalex   +1 more source