Results 61 to 70 of about 230,259 (343)

Application of a developed triple-classification machine learning model for carcinogenic prediction of hazardous organic chemicals to the US, EU, and WHO based on Chinese database

open access: yesEcotoxicology and Environmental Safety, 2023
Cancer, the second largest human disease, has become a major public health problem. The prediction of chemicals’ carcinogenicity before their synthesis is crucial.
Ning Hao   +3 more
doaj   +1 more source

Chemical carcinogenicity revisited 1: A unified theory of carcinogenicity based on contemporary knowledge.

open access: yesRegulatory toxicology and pharmacology : RTP, 2019
Developments in the understanding of the etiology of cancer have profound implications for the way the carcinogenicity of chemicals is addressed. This paper proposes a unified theory of carcinogenesis that will illuminate better ways to evaluate and ...
Douglas C. Wolf   +9 more
semanticscholar   +1 more source

Image1_DeepCarc: Deep Learning-Powered Carcinogenicity Prediction Using Model-Level Representation.tiff

open access: yes, 2021
Carcinogenicity testing plays an essential role in identifying carcinogens in environmental chemistry and drug development. However, it is a time-consuming and label-intensive process to evaluate the carcinogenic potency with conventional 2-years rodent ...
Ting Li (117885)   +4 more
core   +1 more source

Biomimetic Hybrid‐Membrane Nanoreactor for Deep‐Seated Photodynamic Immunotherapy of Hepatocellular Carcinoma via Dual Catalysis‐Enhanced ROS Amplification and cGAS‐STING Activation

open access: yesAdvanced Functional Materials, EarlyView.
UCNP@MnOx‐Hyp@HRM (UMHM) enables tumor targeting and accumulation. Under 808 nm NIR irradiation, PDT/CDT synergistically triggers ICD and cGAS–STING immunity for deep hepatocellular carcinoma therapy. ABSTRACT Photodynamic therapy (PDT) is promising against hepatocellular carcinoma (HCC).
Wen Li   +10 more
wiley   +1 more source

The Carcinogenicity of Arsenic [PDF]

open access: yesEnvironmental Health Perspectives, 1981
A carcinogenic role of inorganic arsenic has been suspected for nearly a century. Exposure to inorganic arsenic compounds occurs in some occupational groups, e.g., among smelter workers and workers engaged in the production and use of arsenic containing pesticides. Substantial exposure can also result from drinking water in certain areas and the use of
openaire   +2 more sources

Strong Fully Reprocessable Engineered Wood Composites

open access: yesAdvanced Materials, EarlyView.
Engineering a hyperbranched adhesive with complementary imine‐bond and hydrogen‐bond networks, combining it with wood particles to fabricate the wood composite (WP/HTP) under mild hot‐pressing conditions. The WP/HTP exhibits 100% mechanical strength recovery after three cycles of reprocessing, and the reprocessed modulus of rupture (MOR) and modulus of
Xilin Zhang   +9 more
wiley   +1 more source

Carcinogenicity of welding, molybdenum trioxide, and indium tin oxide.

open access: yesThe Lancet Oncology, 2017
In March 2017, 17 scientists from ten countries met at the International Agency for Research on Cancer (IARC; Lyon, France) to evaluate the carcinogenicity of welding, molybdenum trioxide, and indium tin oxide.
N. Guha   +9 more
semanticscholar   +1 more source

Table3_DeepCarc: Deep Learning-Powered Carcinogenicity Prediction Using Model-Level Representation.XLSX

open access: yes, 2021
Carcinogenicity testing plays an essential role in identifying carcinogens in environmental chemistry and drug development. However, it is a time-consuming and label-intensive process to evaluate the carcinogenic potency with conventional 2-years rodent ...
Ting Li (117885)   +4 more
core   +1 more source

Machine Learning for Green Solvents: Assessment, Selection and Substitution

open access: yesAdvanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta   +4 more
wiley   +1 more source

2'-Deoxythymidine Adducts from the Anti-HIV Drug Nevirapine

open access: yesMolecules, 2013
Nevirapine (NVP) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used against HIV-1. Currently, NVP is the most widely used anti-HIV drug in developing countries, both in combination therapy and to prevent mother-to-child transmission of HIV.
M. Matilde Marques   +4 more
doaj   +1 more source

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