Results 81 to 90 of about 230,259 (343)

Quantum chemical calculations of nitrosamine activation and deactivation pathways for carcinogenicity risk assessment

open access: yesFrontiers in Pharmacology
N-nitrosamines and nitrosamine drug substance related impurities (NDSRIs) became a critical topic for the development and safety of small molecule medicines following the withdrawal of various pharmaceutical products from the market.
Andreas H. Göller   +3 more
doaj   +1 more source

Toxicity and Carcinogenicity of Dichlorodiphenyltrichloroethane (DDT)

open access: yesToxicological Research, 2016
Dichlorodiphenyltrichloroethane (DDT) is still used in certain areas of tropics and subtropics to control malaria and other insect-transmitted diseases.
T. Harada   +3 more
semanticscholar   +1 more source

Advances in Se Wide‐Bandgap Photovoltaics and TexSe1‐x SWIR Photodiodes

open access: yesAdvanced Science, EarlyView.
In this review, fundamental properties and current challenges in Se photovoltaics (PVs) for tandem and indoor PVs and TexSe1‐x alloys for short wave infrared photodiodes are discussed. A case is made for the practicality of elemental chalcogenide optoelectronics, and a pathway toward resolving the key challenges in these respective technologies is ...
Adam D. Alfieri, Deep Jariwala
wiley   +1 more source

The history of arsenical pesticides and health risks related to the use of Agent Blue

open access: yesAnnals of Agricultural and Environmental Medicine, 2017
Arsenicals in agriculture. Beginning in the 1970s, the use of arsenic compounds for such purposes as wood preservatives, began to grow. By 1980, in the USA, 70% of arsenic had been consumed for the production of wood preservatives.
Vladimir Bencko, Florence Yan Li Foong
doaj   +1 more source

Carcinogenicity of consumption of red and processed meat: What about environmental contaminants?

open access: yesEnvironmental Research, 2016
In October 26, 2015, the International Agency for Research on Cancer (IARC) issued a press release informing of the recent evaluation of the carcinogenicity of red and processed meat consumption.
Josep L. Domingo, M. Nadal
semanticscholar   +1 more source

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

open access: yesAdvanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song   +7 more
wiley   +1 more source

Review of the effect of atrazine on the HPG axes and steroidogenic pathways in males: relevance for testicular and prostate cancer

open access: yesFrontiers in Toxicology
Subacute, subchronic, and chronic rodent studies on atrazine were evaluated to determine the no observed adverse effect levels (NOAEL) for male reproductive toxicity and carcinogenicity.
Ralph L. Cooper   +2 more
doaj   +1 more source

Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans

open access: yesCritical Reviews in Toxicology, 2016
In an evaluation of carbon nanotubes (CNTs) for the IARC Monograph 111, the Mechanisms Subgroup was tasked with assessing the strength of evidence on the potential carcinogenicity of CNTs in humans.
E. Kuempel   +9 more
semanticscholar   +1 more source

Animal Use in Carcinogenicity Studies Supporting Approved New Drug Applications in the U.S., 2015-2019

open access: yes, 2022
Data supports "Animal Use and Opportunities for Reduction in Carcinogenicity Studies Supporting Approved New Drug Applications in the U.S., 2015-2019" in Regulatory Toxicology and Pharmacology.
Manuppello, J (via Mendeley Data)   +1 more
core   +1 more source

Biosynthesis of Spatially Differentiated Cellulose for Flexible All‐in‐one Supercapacitors

open access: yesAdvanced Science, EarlyView.
Spatially differentiated bacterial cellulose is grown by oxygen‐guided biosynthesis to form dense surface regions connected by an open fibrillar interlayer. This architecture supports electroactive material loading, ion transport, and mechanical stability in an all‐in‐one supercapacitor, showing how biological assembly can create device‐ready ...
Xin Shu   +7 more
wiley   +1 more source

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