Results 81 to 90 of about 34,592 (264)

Toxic effects of decabromodiphenyl ether (BDE-209) on human embryonic kidney cells

Frontiers in Genetics, 2014
Polybrominated diphenyl ethers (PBDEs) are widely used as flame-retardant additives in consumer and household products and can escape into the environment over time.
Min eLi, Zhenping eLiu, Liang eGu, Rong eYin, Huarong eLi, Xiaobai eZhang, Tongcheng eCao, Cizhong eJiang   +7 more
doaj   +1 more source

Strategies for inducing diabetes in laboratory animals: Advances from chemical, surgical, immunologic, dietary, and genetic approaches

Animal Models and Experimental Medicine, EarlyView.
This review summarizes the principal experimental approaches used to induce diabetes in animal models. Strategies include chemical agents (streptozotocin, alloxan, dithizone, gold thioglucose), dietary interventions (high‐fat and high‐sugar diets), surgical methods (total or partial pancreatectomy), genetic models (db/db, ob/ob, Goto‐Kakizaki [GK ...
Milad Faraji, Maedeh Faraji, Nasrin Kazemipour   +2 more
wiley   +1 more source

Comparative analysis of TP53 gene in Tupaia belangeri subspecies (Tupaia belangeri yaoshanensis vs. Tupaia belangeri chinensis) and identification of mutations in spontaneous tumor cases

Animal Models and Experimental Medicine, EarlyView.
This study provides the first evidence of natural TP53 variation between tree shrew subspecies and identifies somatic TP53 mutations in spontaneous tree shrew sarcomas. The high structural and functional conservation of tree shrew p53 with humans supports its utility as a relevant model for TP53‐related cancer research.
Yingying Cao, Haibo Tang, Liang Liang, Jing Leng, Weijian Huang   +4 more
wiley   +1 more source

Safety and Feasibility of Magnetic Separation‐Based Blood Purification

Advanced NanoBiomed Research, EarlyView.
We present the preclinical biological safety and translational feasibility of a magnetic nanoparticle‐based extracorporeal blood purification platform for removal of disease‐causing blood factors. ISO 10993‐compliant studies and exaggerated worst‐case exposure models demonstrate efficient nanoparticle extraction (≥99.9%), favorable biocompatibility ...
Carlos A. Mora, Laurine Rijsbergen, Jan Waskowski, Gaelle Clermont, Florian Dingreville, Chandrashekara Vishwanath, Rajesh Karunanithi, Alexander Gogos, Jean‐Claude Metzger, Manuel Baumgartner, Joerg C. Schefold, Inge K. Herrmann   +11 more
wiley   +1 more source

Prediction of the carcinogenic potential of human pharmaceuticals using repeated dose toxicity data and their pharmacological properties

Frontiers in Medicine, 2016
In an exercise designed to reduce animal use, we analysed the results of rat sub-chronic toxicity studies from 289 pharmaceutical compounds with the aim to predict the tumour outcome of carcinogenicity studies in this species.
Jan Willem Van Der Laan, Jan Willem Van Der Laan, Wenny Buitenhuis, Laura Wagenaar, Ans Soffers, Eugene van Someren, Cyrille Krul, Ruud Woutersen, Ruud Woutersen   +8 more
doaj   +1 more source

Synergistic Advanced Oxidation and Physicochemical Treatment Strategies for Antibiotic Removal and Resistance Mitigation in Water

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The presence of antibiotics in water not only causes environmental pollution but also increases the growth of antibiotic‐resistant bacterial genes, which pose serious threats to human beings and other water residents. Large numbers of people are reportedly affected by the resistant bacterial genes, as many broad‐spectrum antibiotics are not ...
Amir Zada, Shohreh Azizi
wiley   +1 more source

Plasma–Kinetic Coupling and Redox Mechanisms in the Degradation of Acid Red 51 by Atmospheric Corona Discharge

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This study investigates the degradation of the xanthene dye Acid Red 51 (ARE‐51) using atmospheric‐pressure corona discharge plasma, integrating electrical characterization, optical emission spectroscopy (OES), kinetic modeling, and physicochemical analysis to establish a unified plasma–liquid interaction framework. A degradation efficiency of
Cristian Mendoza Benítez, Horacio Martínez Valencia, María del Pilar Rodríguez‐Rojas, Pedro Guillermo Reyes Romero, Aaron Gómez Díaz, Josefina Vergara Sánchez, Dalila Martínez Molina, Fermín Castillo Mejía   +7 more
wiley   +1 more source

Occupational Exposure to Inhalable and Respirable Wood Dust of Pedunculate Oak (Quercus robur L.) in a Furniture Factory

BioResources, 2022
Given the well-known carcinogenicity of hardwood dust, occupational exposure to oak wood dust has been determined in a furniture factory on different wood processing machines during sanding, planing, and milling.
Anka Ozana Čavlović, Ivan Bešlić, Stjepan Pervan, Nikolina Barlović, Mislav Mikšik, Miljenko Klarić, Silvana Prekrat   +6 more
doaj  

Preparation of MOEAMCl and MAAm Based Hydrogels and Effective Use in Anionic Dye Adsorption

Journal of Applied Polymer Science, Volume 142, Issue 16, April 20, 2025.
ABSTRACT In this study, hydrogels based on [2‐(Methacryloyloxy)ethyl]trimethylammonium chloride (MOEAMCl) and methacrylamide (MAAm) were synthesized for the removal of anionic dyes from aqueous solutions. Following detailed characterization, the use of hydrogels for methyl orange (MO) adsorption was investigated.
Hilal Nur Duykop Demir, Ali Delibaş, Ayşe Benk, Ramazan Coşkun   +3 more
wiley   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source