Results 101 to 110 of about 3,679,735 (330)

Tailoring a Functional Synthetic Microbial Community Alleviates Fusobacterium nucleatum‐infected Colorectal Cancer via Ecological Control

Advanced Science, EarlyView.
The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou, Mengyue Yang, Hong Fang, Baizhuo Zhang, Yunhao Ma, Yongyuan Li, Yingjie Liu, Zeying Cheng, Yuanchun Zhao, Zhenzhen Si, Hongmei Zhu, Peng Chen   +11 more
wiley   +1 more source

Biomarkers for assessing environmental exposure to carcinogens in the diet.

American Journal of Clinical Nutrition, 1995
The major sources of human exposure to environmental carcinogens are through inhalation, ingestion, and percutaneous absorption. Food-borne carcinogens constitute the primary source of ingested carcinogens.
Paul T. Strickland, J. Groopman
semanticscholar   +1 more source

Breast cancer risk in relation to occupations with exposure to carcinogens and endocrine disruptors: a Canadian case–control study

Environmental Health, 2012
Background Endocrine disrupting chemicals and carcinogens, some of which may not yet have been classified as such, are present in many occupational environments and could increase breast cancer risk. Prior research has identified associations with breast
Brophy James T, Keith Margaret M, Watterson Andrew, Park Robert, Gilbertson Michael, Maticka-Tyndale Eleanor, Beck Matthias, Abu-Zahra Hakam, Schneider Kenneth, Reinhartz Abraham, DeMatteo Robert, Luginaah Isaac   +11 more
doaj   +1 more source

Hybrid Series of Carbon‐Vacancy Electrodes for Multi Chemical Vapors Diagnosis Using a Residual Multi‐Task Model

Advanced Science, EarlyView.
This study presents a graphene oxide‐based gas sensor array integrated with a deep learning framework for precise detection and classification of multiple gases. By combining advanced sensing materials and a 1D‐ResNet architecture, the system achieves high sensitivity and accuracy, demonstrating its potential for real‐time environmental monitoring ...
Tianci Liu, Yun Ji Hwang, Lu Zhang, Jongwoo Hong, Teajong Hwang, Seong Chan Jun   +5 more
wiley   +1 more source

Summary of Workshop to Review an OMB Report on Regulatory Risk Assessment and Management [PDF]

, 1992
Summary of the results of an invitational workshop conducted to peer review the 1990 OMB report, CURRENT REGULATORY ISSUES IN Risk ASSESSMENT AND Risk MANAGENMENTIN REGULATORY PROGRAM OF THE UNITED STATES GOVERNMENT, APRIL 1, 1990 - MARCH 31 ...
Evans, John S., Graham, John D., Gray, George M., Hollis, Adrienne   +3 more
core   +2 more sources

Establishing a Policy Framework for the Primary Prevention of Occupational Cancer: A Proposal Based on a Prospective Health Policy Analysis

Safety and Health at Work, 2017
Background: Despite our knowledge of the causes of cancer, millions of workers are involuntarily exposed to a wide range of known and suspected carcinogens in the workplace. To address this issue from a policy perspective, we developed a policy framework
Amanda Veglia, Manisha Pahwa, Paul A. Demers   +2 more
doaj   +1 more source

Plasma DNMT1 Activity for Assessing Tumor Burden and Predicting Neoadjuvant Therapy Response in Breast Cancer

Advanced Science, EarlyView.
In this work, a detection method is presented for the activity of plasma DNA methyltransferase 1 (DNMT1), namely DNMT1 Identification by Variable Activity (DIVA). DIVA can detect plasma DNMT1 at levels as low as 10−7 U mL−1, also it successfully evaluated tumor burden and predicted the neoadjuvant therapy responses of breast cancer patients.
Yingran Wang, Guozhi Zhang, Zhizhao Zhang, Mengsi Zhang, Jiao Chen, Ke Wang, Lu Liu, Jing Bao, Ming Chen, Xiaowei Qi, Mingxuan Gao   +10 more
wiley   +1 more source

Future directions in the use of DNA adducts as internal dosimeters for monitoring human exposure to environmental mutagens and carcinogens.

Environmental Health Perspectives, 1985
Scientific opportunities generally arise when two or more research areas converge and/or advances in methodology occur. This occurred at the turn of the 19th century in the field of infectious bacterial and fungal diseases.
C. Harris
semanticscholar   +1 more source

Occupational Exposure to Polycyclic Aromatic Hydrocarbons and Elevated Cancer Incidence in Firefighters [PDF]

, 2018
Cancer incidence appears to be higher amongst firefighters compared to the general population. Given that many cancers have an environmental component, their occupational exposure to products of carbon combustion such as polycyclic aromatic hydrocarbons (
Dickens, Kathryn, Hewitt, Fiona E., Houldsworth, Philip Edwin, Martin, Francis L, Salden, Marielle Louise, Stec, Anna A, Watts, Damian P   +6 more
core   +2 more sources

BPDE induces human trophoblast cell ferroptosis by up-regulating iron metabolism and promoting GPX4 proteasomal degradation

Ecotoxicology and Environmental Safety, 2021
Human trophoblast cells play important role in embryo-fetal development. However, trophoblast cells are sensitive to environmental carcinogens. Recently, we have discovered that BPDE inhibits trophoblast cell migration, invasion and proliferation, and ...
Peng Tian, Zhongyan Xu, Jiarong Guo, Jingsong Zhao, Rong Wang, Weina Chen, Yang Yang, Wenxin Huang, Chenyang Mi, Huidong Zhang   +9 more
doaj