Results 141 to 150 of about 35,315 (245)

Carcinogenicity of vinyl acetate: evidence from multiple data streams. [PDF]

Environ Health
Li K, Ricker K, Tsai FC, Cheng V, Osborne G, Guha N, Elmore S, Alvarado-Cruz I, Sandy MS, Sun M.   +9 more
europepmc   +1 more source

Consensus findings of an International Workshops on Genotoxicity Testing workshop on using transcriptomic biomarkers to predict genotoxicity

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl, J. Christopher Corton, Henghong Li, Jiri Aubrecht, Scott S. Auerbach, Florian Caiment, Tatyana Y. Doktorova, Yurika Fujita, Danyel Jennen, Naoki Koyama, Matthew J. Meier, Roman Mezencev, Leslie Recio, Takayoshi Suzuki, Carole L. Yauk   +14 more
wiley   +1 more source

Development of Korean CARcinogen EXposure: IARC Group 2A Carcinogens. [PDF]

Saf Health Work
Koh DH, Choi S, Park JH, Lee SG, Kim HC, Kim I, Min J, Kim Y, Lee J, Park DU.   +9 more
europepmc   +1 more source

Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li, Jiri Aubrecht, Tatyana Y. Doktorova, Danyel Jennen, J. Christopher Corton, Roland Froetschl, Roman Mezencev, Carole L. Yauk   +7 more
wiley   +1 more source

Assessment of chemical risk factor for breast cancer based on gene expression profiles. [PDF]

Sci Rep
Achebouche R, Taboureau O.
europepmc   +1 more source

Sustainable polypropylene chair: A life cycle assessment and cost analysis of industrial production

Environmental Progress &Sustainable Energy, EarlyView.
Abstract Due to their multiple properties, including flexibility, lightness, and strength, thermoplastics are an essential material in the development of processes at both industrial and domestic levels. However, thermoplastics are often derived from polymers synthesized using non‐renewable petroleum resources. This has environmental consequences.
Lucrezia Maggi, Alberto Pietro Damiano Baltrocchi, Marco Carnevale Miino, Elena Cristina Rada, Vincenzo Torretta   +4 more
wiley   +1 more source

A multi‐level approach for multi‐objective optimization in process eco‐design

Environmental Progress &Sustainable Energy, EarlyView.
Abstract This work addresses a central challenge in process eco‐design: how to efficiently integrate environmental and economic criteria—often conflicting—into early design stages while managing the high dimensionality of Life Cycle Assessment (LCA) indicators.
Luis Fernando Morales‐Mendoza, Catherine Azzaro‐Pantel, Ingrid Eileen Ortega‐Gutiérrez, Iris Abril Martínez‐Salazar   +3 more
wiley   +1 more source

Epigenetic Changes Induced by Carcinogenic Agents or Occupational Exposure with Sufficient Evidence for Bladder Cancer. [PDF]

Cancer Prev Res (Phila)
Kasperczyk E, Tarhonska K, Jablonska E.
europepmc   +1 more source

Alginate Oligosaccharides Attenuate Ochratoxin A‐Induced Liver Injury through Regulating the Interaction of Nrf2 and NF‐κB Signaling Pathways

Food Frontiers, EarlyView.
A schematic illustration for the protective effects of AOS on OTA‐induced liver injury in mice. AOS, alginate oligosaccharides; CAT, catalase; GSTT1, glutathione S‐transferase theta 1; HO‐1, heme oxygenase 1; IκBα, inhibitor kappa B alpha; IL‐1β, interleukin‐1β; IL‐6, interleukin‐6; Keap1, kelch‐like ech‐associated protein 1; NF‐κB, nuclear factor ...
Yue Zhao, Xueqing Ye, Yan Guo, Zhongxiang Zhao, Qinghua Yao, Yaoyao Wang, Huimei Liu, Ziwei Lin, Wenchao Liu   +8 more
wiley   +1 more source

Causes of Childhood Cancer: A Literature Review (2014-2021)-Part 3: Environmental and Occupational Factors. [PDF]

Cancers (Basel)
Emeny RT, Butow ME, Titus L, Ricci AM, Bagley PJ, Blunt HB, Morgan A, Alford-Teaster JA, Walston RR, Rees JR.   +9 more
europepmc   +1 more source