Carcinogenicity of vinyl acetate: evidence from multiple data streams. [PDF]
Li K +9 more
europepmc +1 more source
Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl +14 more
wiley +1 more source
Development of Korean CARcinogen EXposure: IARC Group 2A Carcinogens. [PDF]
Koh DH +9 more
europepmc +1 more source
Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines
ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li +7 more
wiley +1 more source
Assessment of chemical risk factor for breast cancer based on gene expression profiles. [PDF]
Achebouche R, Taboureau O.
europepmc +1 more source
Sustainable polypropylene chair: A life cycle assessment and cost analysis of industrial production
Abstract Due to their multiple properties, including flexibility, lightness, and strength, thermoplastics are an essential material in the development of processes at both industrial and domestic levels. However, thermoplastics are often derived from polymers synthesized using non‐renewable petroleum resources. This has environmental consequences.
Lucrezia Maggi +4 more
wiley +1 more source
A multi‐level approach for multi‐objective optimization in process eco‐design
Abstract This work addresses a central challenge in process eco‐design: how to efficiently integrate environmental and economic criteria—often conflicting—into early design stages while managing the high dimensionality of Life Cycle Assessment (LCA) indicators.
Luis Fernando Morales‐Mendoza +3 more
wiley +1 more source
Epigenetic Changes Induced by Carcinogenic Agents or Occupational Exposure with Sufficient Evidence for Bladder Cancer. [PDF]
Kasperczyk E, Tarhonska K, Jablonska E.
europepmc +1 more source
A schematic illustration for the protective effects of AOS on OTA‐induced liver injury in mice. AOS, alginate oligosaccharides; CAT, catalase; GSTT1, glutathione S‐transferase theta 1; HO‐1, heme oxygenase 1; IκBα, inhibitor kappa B alpha; IL‐1β, interleukin‐1β; IL‐6, interleukin‐6; Keap1, kelch‐like ech‐associated protein 1; NF‐κB, nuclear factor ...
Yue Zhao +8 more
wiley +1 more source
Causes of Childhood Cancer: A Literature Review (2014-2021)-Part 3: Environmental and Occupational Factors. [PDF]
Emeny RT +9 more
europepmc +1 more source

