Results 171 to 180 of about 3,679,735 (330)

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

Hepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro, Rut Espinosa‐Sotelo, Eva Crosas‐Molist, Macarena Herranz‐Itúrbide, Daniel Caballero‐Díaz, Ania Alay, Xavier Solé, Emilio Ramos, Teresa Serrano, María L. Martínez‐Chantar, Ulla G. Knaus, José M. Cuezva, Antonio Zorzano, Esther Bertran, Isabel Fabregat   +14 more
wiley   +1 more source

Childhood Leukemia Clusters in Yemen: The Dual Impact of Environmental Carcinogens and Healthcare Collapse in Conflict Zones. [PDF]

Cureus
AlQubati AN.
europepmc   +1 more source

Review of recent advances in the design, synthesis, and modification of biochar for remediation of heavy metal pollution in water

The Canadian Journal of Chemical Engineering, EarlyView.
Research frontiers in using biochar for heavy metal remediation. Abstract Heavy metal contamination of water has long been a serious environmental issue. Biochar and biochar‐based composites are emerging as effective and sustainable solutions for heavy metal removal due to their strong adsorption abilities and environmentally friendly nature.
Soumik Chakma, Mehedi Hasan, Sudip K. Rakshit, Janusz Kozinski, Kang Kang   +4 more
wiley   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source

Mapping assays to the key characteristics of carcinogens to support decision-making. [PDF]

Database (Oxford)
Rigutto G, McHale CM, Singam ERA, Rana I, Zhang L, Smith MT.   +5 more
europepmc   +1 more source

Charge State Influence on Stability and Isomerism in Dehydrogenated PAHs: Insights from Anthracene, Acridine, and Phenazine

ChemPhysChem, Volume 26, Issue 6, March 15, 2025.
The ionization of anthracene, acridine, and phenazine has been explored, along with the removal of one and two hydrogen atoms, to provide valuable information for astrochemists and to understand the behavior of the resulting structures and their electronic reorganization. Abstract In this study, we systematically explored the stability and isomerism of
Khaldia Zghida, Farouk Hamza Reguig, Manuel Alcamí, Al Mokhtar Lamsabhi   +3 more
wiley   +1 more source

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

Hepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie, Jill E. Hunter, Amy Collins, Amelia Rushton, Lauren G. Russell, Erik Ramon‐Gil, Maja Laszczewska, Misti McCain, Marco Y. W. Zaki, Amber Knox, Yixin Seow, Laura Sabater, Daniel Geh, Neil D. Perkins, Helen L. Reeves, Dina Tiniakos, Derek A. Mann, Fiona Oakley   +17 more
wiley   +1 more source

Environmental causes of cancer: endocrine disruptors as carcinogens

Nature Reviews Endocrinology, 2010
A. Soto, C. Sonnenschein
semanticscholar   +1 more source

The key characteristics concept. [PDF]

Curr Opin Toxicol
Smith MT.
europepmc   +1 more source

Adsorption of Mercury in Aqueous Solutions by Functionalized Cellulose Extracted from Soybean Hulls

ChemPlusChem, EarlyView.
Reuse of agricultural waste as a source of adsorbent cellulose‐based materials is a low‐cost and sustainable approach to remove potentially toxic elements (PTEs) from aqueous solutions. This approach is successfully applied in the removal of mercury from aquaculture water, an important source of food where the absence of PTEs is a fundamental requisite
Monica Rigoletto, María Rapp, Amaya Arencibia, María‐José López‐Muñoz, Maria Laura Tummino, Nieves Fernández de Paz, Enzo Laurenti   +6 more
wiley   +1 more source