Results 211 to 220 of about 372,123 (339)

Carcinogenicity studies

Folia Pharmacologica Japonica, 2007
openaire   +3 more sources

Navigating the Genetic Risk of Chemotherapy‐Induced Hearing Loss in the Stria Vascularis

Clinical Pharmacology &Therapeutics, EarlyView.
Cisplatin is a chemotherapy drug that causes permanent hearing loss by damaging a critical tissue lining the inner ear, called the stria vascularis (SV). Currently, the molecular mechanisms of SV damage are largely unknown and the incidence of ototoxicity in patients cannot be reliably predicted.
Tara Lazetic, Deanne Nixie R. Miao, Britt I. Drögemöller, Alain Dabdoub, Julia M. Abitbol   +4 more
wiley   +1 more source

Environmental carcinogens often exacerbate endogenous mutagenic processes to enhance tumor promotion. [PDF]

Cell Rep
Xu M, Li J, Hsiao YC, Kovi RC, Li JL, Klimczak LJ, Riva L, Adams D, Bushel PR, Merrick BA, Gordenin D, Bucher JR, Sills RC, Pandiri AR.   +13 more
europepmc   +1 more source

Exposure and Metabolic Activation Biomarkers of Carcinogenic Tobacco-Specific Nitrosamines

, 2015
Stephen S. Hecht, Irina Stepanov, Steven G. Carmella   +2 more
openalex   +2 more sources

Foodborne trematodes: a diverse and challenging group of neglected parasites [PDF]

, 2017
Blair, Doanh, Joanne P. Webster, Kamsa-ard, Lai, Paiboon Sithithaworn, Pakharukova, Pérez-Ponce de León, Ross H. Andrews, Saijuntha, Tantrawatpan, Toledo, Trevor N. Petney, Valero   +13 more
core   +1 more source

PharmVar GeneFocus: NAT2—Genetic Variation and Updated Nomenclature

Clinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human N‐acetyltransferase 2 (NAT2) gene. NAT2 metabolizes several clinically used drugs including isoniazid, hydralazine, amifampridine, procainamide, and sulfonamides such as dapsone, and also some highly carcinogenic arylamines.
Georgia Papanikolaou, Estella S. Poloni, José A.G. Agúndez, Raquel L.F. Teixeira, Erin C. Boone, Adalberto Rezende Santos, Michelle Whirl‐Carrillo, Katrin Sangkuhl, Teri E. Klein, Mariam R. Habil, Giannoulis Fakis, Rodney F. Minchin, David W. Hein, Sotiria Boukouvala, Andrea Gaedigk   +14 more
wiley   +1 more source

The science behind safety in our daily life: the open symposium of the Japanese environmental mutagen and genome society (JEMS), 2025. [PDF]

Genes Environ
Koyama N, Tsuda M.
europepmc   +1 more source

Transformation of BALB/c-3T3 cells: V. Transformation responses of 168 chemicals compared with mutagenicity in Salmonella and carcinogenicity in rodent bioassays.

, 1993
Edwin J. Matthews, Judson W. Spalding, Raymond W. Tennant   +2 more
openalex   +1 more source

Do Firms Hoard Cash Under Environmental Pressure? Insights From GHG Emissions and Greenwashing Activities

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Environmental accountability has become a global priority, with governments implementing policies like the Kyoto Protocol and the Paris Agreement. However, many firms continue to operate outside environmentally ethical standards, facing potential regulatory, financial, and reputational risks.
Ones Amri, Davide Calandra, Paolo Biancone, Hasna Chaibi   +3 more
wiley   +1 more source

Guidelines for the assessment and control of mutagenic impurities in pharmaceuticals. [PDF]

Genes Environ
Honma M.
europepmc   +1 more source