Results 31 to 40 of about 310,687 (304)
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2022 The development of effective and safe therapeutic agents using 1,2,4-triazole derivatives is gaining momentum in today’s conditions. The value of such drugs is determined by the rapid and prolonged biological action, which is not accompanied by abrupt ...
I. V. Bushuieva +3 more
doaj +1 more source
Aflatoxin B1-induced changes of glutathione-S-transferase activity in the plasma and liver of the rat [PDF]
Vojnosanitetski Pregled, 2003 Background. The influence of low doses of aflatoxin B1 (AFB1) and partial hepatectomy (PH) on glutathione-S-transferase (GST) activity was studied in the plasma and liver of the rat. Methods. The animals were divided into four groups.
Strelić Nataša J. +5 more
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Quantitative Assessment of Organic and Inorganic Contaminants in Charcoal
Resources, 2021 Thirty-one batches of commercial charcoal from various regions of Poland and Germany were tested for the presence of 20 toxic elements and polycyclic aromatic hydrocarbons (PAHs) using gas chromatography-mass spectrometry (GC-MS). Elements that are toxic
Zbigniew Jelonek +2 more
doaj +1 more source
Are there thresholds for carcinogens carcinogenicity?
Mycotoxins, 2008 魚や肉などの焼けこげに含まれている2-amino-3,8-dimethylimidazo[4,5-f ] quinoxaline（MeIQx）のラット肝臓における低用量発がん性を中期発がん性試験法で検討した．その結果，MeIQx?DNA 付加体形成は微量からみられ，より高い用量で8-hydroxy-2′-deoxyquanosine 形成，lacI 遺伝子変異，イニシエーション活性等が誘発された．また，肝臓の前腫瘍性病変であるglutahione S-transferase placental（GST-P）陽性細胞巣は，さらにより高い用量で誘発された．N- ニトロソ化合物であるN-nitrosodiethylamine やN-nitrosodimethylamine でもGST-P ...
FUKUSHIMA, Shoji +3 more
openaire +2 more sources
Reducing occupational exposure to chemical carcinogens [PDF]
, 2009 Strategies for controlling occupational exposure to chemical carcinogens are set out in the European Union Carcinogens Directive and in national legislation such as the British Control of Substances Hazardous to Health Regulations. While such legislative
Cherrie, John W.; id_orcid +1 more
core +1 more source
Carcinogens and DNA damage [PDF]
, 2018 Humans are variously and continuously exposed to a wide range of different DNA-damaging agents, some of which are classed as carcinogens. DNA damage can arise from exposure to exogenous agents, but damage from endogenous processes is probably far more ...
Poirier, Miriam C +4 more
core +1 more source
, 2022 S.217-224Carcinogens are generally classified into two Groups: genotoxic and non-genotoxic. As the final product of genotoxic and non-genotoxic carcinogens is the same, i.e., a clone of genetically altered cells, it could be possible that non-genotoxic ...
Fahrig, R., Steinkamp-Zucht, A.
core +1 more source
NIOSH chemical carcinogen policy [PDF]
Occupational exposure to chemical carcinogens still presents risks to many in the workforce. The burden from exposure to occupational carcinogens on workers, their families, employers, and the nation is difficult to measure.
core +3 more sources
Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer
eLife, 2021 Determining the etiologic basis of the mutations that are responsible for cancer is one of the fundamental challenges in modern cancer research. Different mutational processes induce different types of DNA mutations, providing ‘mutational signatures ...
Bahman Afsari +12 more
doaj +1 more source
Biotechnologie, Agronomie, Société et Environnement, 2022 Risk associated with the presence of mycotoxins (aflatoxins and ochratoxin A) in foodstuffs: the case of fermented fish (adjuevan) marketed in Abidjan (Côte d’Ivoire) Description of the subject.
Kouakou Gains Kpan Kpan +3 more
doaj +1 more source