Results 51 to 60 of about 5,912,858 (156)

Knowledge gaps in tubular gut tumours: a critical appraisal of the 6th edition of the World Health Organization classification of tumours

open access: yesThe Journal of Pathology, Volume 270, Issue 1, Page 4-22, September 2026.
Abstract Gastrointestinal cancer is a global health problem. In the new 6th edition of the World Health Organization Classification of Tumours (WCT) of the Digestive System, updated evidence and guidance is provided for the aetiology, pathogenesis, diagnosis, classification, grading, staging and prognosis of these tumours.
Iris D Nagtegaal   +5 more
wiley   +1 more source

Carcinoid heart disease: A pictorial report

open access: yesJournal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2017
Carcinoid tumors are rare, mostly seen in gastrointestinal tract and bronchus. Carcinoid heart disease occurs in up to half of these patients with characteristic involvement of right-sided valves.
Amit Kumar   +3 more
doaj   +1 more source

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 345-356, August 2026.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le   +8 more
wiley   +1 more source

Harnessing Exhaled Breath for Lung Cancer Early Detection—Results From the ExPeL Study

open access: yesClinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT Scalable, non‐invasive tools are critically needed to improve early lung cancer detection and optimize primary care referral pathways. We evaluated Inflammacheck, a point‐of‐care device utilizing exhaled breath condensate (EBC) H2O2 and physiological parameters with machine learning for non‐invasive lung cancer detection in a real‐world ...
Danita Kasi Patel   +7 more
wiley   +1 more source

Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue S4, Page 3-16, August 2026.
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib   +3 more
wiley   +1 more source

Carcinoid Heart Disease and a Primary Ovarian Carcinoid Tumor

open access: yes, 2018
Introduction Primary ovarian carcinoid tumors account for less than 0.5% of all carcinoid tumors [1]. Patients with primary ovarian carcinoid tumors may develop carcinoid heart disease by release of bioactive amines directly into the inferior vena cava ...
Konstadinos Plestis (4059451)   +3 more
core   +1 more source

Carcinoid Heart Disease Associated with Primary Ovarian Carcinoid Tumor: A Rare Presentation

open access: yesHeart Views
Primary ovarian carcinoid tumors, an extremely rare subset of ovarian malignancies (
Rawaha Ahmad   +4 more
doaj   +1 more source

Echocardiographic imaging of tricuspid and pulmonary valve abnormalities in primary ovarian carcinoid tumor

open access: yesCardiovascular Ultrasound, 2010
Carcinoid is a rare malignancy originating from enterochromaffin cells and is clinically characterized by flushing, diarrhea and bronchospasm, due to secretion of vasoactive substances.
Aggeli Constantina   +6 more
doaj   +1 more source

Are respiratory physicians adherent to guidelines when evaluating pulmonary nodules?

open access: yesInternal Medicine Journal, Volume 56, Issue 8, Page 1412-1420, August 2026.
Abstract Introduction Although fewer than 1% of pulmonary nodules are malignant, appropriate evaluation is essential in optimising patient outcomes. The 2017 Fleischner Society Guidelines provide recommendations on management of incidentally detected nodules; however, studies to date have shown variable guideline adherence.
Laura Tu   +5 more
wiley   +1 more source

Granulosa Cell Tumour in a Spayed Cat With Ovarian Remnant Syndrome and Hyperestrogenaemia Without Estrus Signs

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Granulosa cell tumour arising from ovarian remnant tissue can occur in spayed cats without overt estrus signs, despite marked hyperestrogenaemia. In this case, CT showed a large abdominal mass contiguous with ovarian vasculature; surgery and histopathology confirmed granulosa cell tumour with hepatic metastasis.
Hitomi Shinoda   +4 more
wiley   +1 more source

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