Results 1 to 10 of about 126,424 (264)

Neuroendocrine Tumors [PDF]

Journal of the National Comprehensive Cancer Network, 2012
Neuroendocrine tumors comprise a broad family of tumors, the most common of which are carcinoid and pancreatic neuroendocrine tumors. The NCCN Neuroendocrine Tumors Guidelines discuss the diagnosis and management of both sporadic and hereditary neuroendocrine tumors. Most of the recommendations pertain to well-differentiated, low- to intermediate-grade
Matthew H, Kulke, Al B, Benson, Emily, Bergsland, Jordan D, Berlin, Lawrence S, Blaszkowsky, Michael A, Choti, Orlo H, Clark, Gerard M, Doherty, James, Eason, Lyska, Emerson, Paul F, Engstrom, Whitney S, Goldner, Martin J, Heslin, Fouad, Kandeel, Pamela L, Kunz, Boris W, Kuvshinoff, Jeffrey F, Moley, Venu G, Pillarisetty, Leonard, Saltz, David E, Schteingart, Manisha H, Shah, Stephen, Shibata, Jonathan R, Strosberg, Jean-Nicolas, Vauthey, Rebekah, White, James C, Yao, Deborah A, Freedman-Cass, Mary A, Dwyer   +27 more
openaire   +3 more sources

Pasireotide for Refractory Hypoglycemia in Malignant Insulinoma- Case Report and Review of the Literature

Frontiers in Endocrinology, 2022
Malignant insulinomas are functional neuroendocrine tumors of the pancreas and the primary cause of tumor-related hypoglycemia. Malignant insulinoma is rare and has a poor prognosis.
Sandrine Oziel-Taieb, Jemima Maniry-Quellier, Brice Chanez, Flora Poizat, Jacques Ewald, Patricia Niccoli   +5 more
doaj   +1 more source

Methylmalonic acid promotes colorectal cancer progression via activation of Wnt/β-catenin pathway mediated epithelial–mesenchymal transition

Cancer Cell International, 2023
Background It has been manifested in several studies that age-related metabolic reprogramming is associated with tumor progression, in particular, colorectal cancer (CRC).
Chunhua Hu, Mujie Ye, Jianan Bai, Pengfei Liu, Feiyu Lu, Jinhao Chen, Ping Yu, Tiaotiao Chen, Xiaoting Shi, Qiyun Tang   +9 more
doaj   +1 more source

Gastric Neuroendocrine Tumor [PDF]

The Surgery Journal, 2021
AbstractGastric neuroendocrine tumor (gNET) is a rare carcinoid of the stomach whose incidence is increasing due to widespread use of upper gastrointestinal endoscopy (UGIE). There are four types of gNETs with different management strategies and prognosis. Here, we present a patient who came with abdomen pain and intermittent melena.
Naresh Kargwal, Viraj Panda, Abhijeet Kumar Jha, C. B. Singh   +3 more
openaire   +3 more sources

Chemotherapy in Neuroendocrine Tumors [PDF]

Cancers, 2021
The role for cytotoxic chemotherapy in patients with well-differentiated neuroendocrine tumors (NETs) remains debated. Compared to patients with poorly differentiated neuroendocrine carcinomas (NECs) where chemotherapy is utilized ubiquitously, chemotherapy may play a more select role in patients with certain types of NETs (e.g., pancreatic tumors ...
Satya Das, Taymeyah Al-Toubah, Jonathan Strosberg   +2 more
openaire   +2 more sources

Down-regulated FTO and ALKBH5 co-operatively activates FOXO signaling through m6A methylation modification in HK2 mRNA mediated by IGF2BP2 to enhance glycolysis in colorectal cancer

Cell & Bioscience, 2023
Background N6-methyladenosine (m6A) modification is the most abundant reversible methylation modification in eukaryotes, and it is reportedly closely associated with a variety of cancers progression, including colorectal cancer (CRC).
Mujie Ye, Jinhao Chen, Feiyu Lu, Minghui Zhao, Suwen Wu, Chunhua Hu, Ping Yu, Jingbao Kan, Jianan Bai, Ye Tian, Qiyun Tang   +10 more
doaj   +1 more source

ALKBH5 enhances lipid metabolism reprogramming by increasing stability of FABP5 to promote pancreatic neuroendocrine neoplasms progression in an m6A-IGF2BP2-dependent manner

Journal of Translational Medicine, 2023
The process of post-transcriptional regulation has been recognized to be significantly impacted by the presence of N6-methyladenosine (m6A) modification.
Jinhao Chen, Mujie Ye, Jianan Bai, Zhihui Gong, Lijun Yan, Danyang Gu, Chunhua Hu, Feiyu Lu, Ping Yu, Lin Xu, Yan Wang, Ye Tian, Qiyun Tang   +12 more
doaj   +1 more source

Neuroendocrine Tumors of the Thymus [PDF]

Thoracic Surgery Clinics, 2011
Neuroendocrine tumors of the thymus (NETTs) are unusual thymic neoplasms that were misdiagnosed as thymomas until the 1970s, when they eventually acquired a distinct identity. No collective large series have been published so far, and information about clinical presentation, diagnosis, histology, and treatment is derived from analysis of the case ...
RUFFINI, Enrico, OLIARO, Alberto, Novero D, Campisi P, FILOSSO, Pier Luigi   +4 more
openaire   +3 more sources

Neuroendocrine Tumor of the Gallbladder [PDF]

Polish Journal of Radiology, 2015
The primary neuroendocrine tumors of the gallbladder are very rare, representing 0.2% of all neuroendocrine tumors. The definite diagnosis is incidental in most cases.A 60-year-old male patient presented with a one-month history of epigastric pain and jaundice, itching, flushing, cough and wheezing.
Monier, Ahmed, Saloum, Nehal, Szmigielski, Wojciech, Alrashid, Amal, Napaki, Sarbar M. E.   +4 more
openaire   +3 more sources

Fishing for neuroendocrine tumors [PDF]

Endocrine-Related Cancer, 2020
Neuroendocrine tumors (NETs) are a class of rare and heterogeneous neoplasms that originate from the neuroendocrine system. In several cases, these neoplasms can release bioactive hormones leading to characteristic clinical syndromes and hormonal dysregulations with detrimental impact on the quality of life and survival of these patients.
Gaudenzi G., Carra S., Dicitore A., Cantone M. C., Persani L., Vitale G.   +5 more
openaire   +2 more sources