Results 71 to 80 of about 711,467 (262)

Biochemical factors in the blood serum of neuroendocrine tumor patients with carcinoid syndrome

Успехи молекулярной онкологии, 2022
Introduction. Carcinoid syndrome is the most common functional syndrome in patients with neuroendocrine tumors. More than 40 biochemical factors are responsible for the manifestation of carcinoid syndrome, among which serotonin is the most important. The
N. V. Lyubimova, Yu. S. Timofeev, A. V. Lebedeva, A. V. Artamonova, I. S. Stilidi, N. E. Kushlinskii   +5 more
doaj   +1 more source

Chromogranin A: From Laboratory to Clinical Aspects of Patients with Neuroendocrine Tumors [PDF]

, 2018
Background. Neuroendocrine tumors (NETs) are characterized by having behavior and prognosis that depend upon tumor histology, primary site, staging, and proliferative index.
Baldelli, Roberto, Campana, Davide, Di Giacinto, Paola, Isidori, Andrea, Lania, Andrea, Lenzi, Andrea, Rizza, Laura, Rota, Francesca, Zuppi, Paolo   +8 more
core   +1 more source

The role of N‐terminal pro‐brain natriuretic peptide, chromogranin A, and 5‐hydroxyindoleacetic acid in screening for carcinoid heart disease

Journal of neuroendocrinology, 2023
Carcinoid heart disease (CHD) is a serious complication for patients with neuroendocrine tumors (NETs), and early detection is crucial. We aimed to investigate N‐terminal pro‐brain natriuretic peptide (NT‐proBNP), chromogranin A (CgA), and plasma 5 ...
Karen Kristina Nyvold Johnson, Tobias Stemann Lau, Simon Mark Dahl Baunwall, Gerda Elisabeth Villadsen, Vibeke Guldbrand Rasmussen, H. Grønbaek, Riina Karoliina Oksjoki, G. Dam   +7 more
semanticscholar   +1 more source

MEN1 Gene mutation and reduced expression are associated with poor prognosis in pulmonary carcinoids [PDF]

, 2014
Context: MEN1 gene alterations have been implicated in lung carcinoids, but their effect on gene expression and disease outcome is unknown. Objective: Our objective was to analyze MEN1 gene and expression anomalies in lung neuroendocrine neoplasms and ...
Corbo, Vicenzo, Gatti, Gaia, Henfling, Mieke ER, Papotti, Mauro, Perren, Aurel, Ramaekers, Frans CS, Scarpa, Aldo, Speel, Ernst-Jan M, Swarts, Dorian RA, Van Criekinge, Wim, van Engeland, Manon, Volante, Marco   +11 more
core   +9 more sources

Telotristat ethyl in carcinoid syndrome: safety and efficacy in the TELECAST phase 3 trial [PDF]

, 2018
Telotristat ethyl, a tryptophan hydroxylase inhibitor, was efficacious and well tolerated in the phase 3 TELESTAR study in patients with carcinoid syndrome (CS) experiencing ≥4 bowel movements per day (BMs/day) while on somatostatin analogs (SSAs ...
Anthony, Lowell B., Benavent, Marta, Fleming, Douglas, Fleming, Rosanna, Garcia-Carbonero, Rocio, Gross, David J., Hörsch, Dieter, Jiang, Wenjun, Kassler-Taub, Kenneth, Kulke, Matthew K., Kunz, Pamela L., Lapuerta, Pablo, Pavel, Marianne, Perros, Petros, Srirajaskanthan, Raj, Warner, Richard R. P., Wason, Suman, Weickert, Martin O.   +17 more
core   +2 more sources

Patent foramen ovale in carcinoid heart disease: The potential role for and risks of percutaneous closure prior to cardiothoracic surgery

Journal of neuroendocrinology, 2023
Neuroendocrine tumours (NETs) are rare but once metastasised, can lead to the release of vasoactive substances into the systemic circulation, and the classical features of carcinoid syndrome (CS) such as flushing and diarrhoea.
Sasha Douglas, T. Oelofse, T. Shah, S. Rooney, S. Arif, R. Steeds   +5 more
semanticscholar   +1 more source

The association of a panel of biomarkers with the presence and severity of carcinoid heart disease: a cross-sectional study.

PLoS ONE, 2013
PurposeMetastatic neuroendocrine tumors secrete serotonin and other vasoactive substances that are responsible for carcinoid syndrome and carcinoid heart disease.
Rebecca Dobson, Malcolm I Burgess, Melissa Banks, D Mark Pritchard, Jiten Vora, Juan W Valle, Christopher Wong, Carrie Chadwick, Keith George, Brian Keevil, Joanne Adaway, Joy E S Ardill, Alan Anthoney, Uschi Hofmann, Graeme J Poston, Daniel J Cuthbertson   +15 more
doaj   +1 more source

Metabolic Signatures of Lung Cancer in Biofluids: NMR-Based Metabonomics of Blood Plasma [PDF]

, 2011
In this work, the variations in the metabolic profile of blood plasma from lung cancer patients and healthy controls were investigated through NMR-based metabonomics, to assess the potential of this approach for lung cancer screening and diagnosis.
Ana Gomes, Ana M. Gil, António S. Barros, Asiago V. M., Bathe O. F., Bell J. D., Brian J. Goodfellow, Brière J.-J., Carrola J., Cláudia M. Rocha, Daykin C. A., Dong J., Duarte I. F., Duarte I. F., Erol A., Fan T. W. M., Fiorenza A. M., Fiorenza A. M., Freedman D. S., Gao H., Gao H. C., Gu H. W., Haffner H. T., Heber D., Iola F. Duarte, Isabel M. Carreira, Joana Carrola, João Bernardo, Jordan K. W., Keun H. C., Kochhar S., Lai H.-S., Laiakis E. C., Lin L., Lina Carvalho, Liu M., Lokhov P. G., Ludwig C., Ma Y., MacIntyre D. A., Maeda J., Muntoni S., Naini A. B., Norton J. A., Okamoto N., Pirozynski M., Psychogios N., Qiu Y. P., Ritchie S. A., Rocha C. M., Sitter B., Spratlin J. L., Sreekumar A., Stringer K. A., Thysell E., Tiziani S., Travis W. D., Trygg J., Urayama S., Vitor Sousa, Xu Q. S., Xue R., Yin P., Zhang J. A., Zhang Z. Y., Zhou J., Zira A. N.   +66 more
core   +2 more sources

Carcinoid Heart Disease – A Review of Pathophysiology, Clinical Manifestations, Diagnosis and Management

Cardiovascular Innovations and Applications, 2023
Objective: Neuro-endocrine tumors (NET) resulting in syndromes of serotonin excess can lead to cardiac involvement, and substantial mortality and morbidity.
S. Ghanta, S. Vallurupalli
semanticscholar   +1 more source

A rare case of thymic carcinoid presenting with gastrointestinal symptoms and pericardium effusion

BMC Cardiovascular Disorders, 2021
Background Thymic carcinoid is one of an extremely rare type of malignant neuroendocrine tumor with a poor prognosis. Invasion of thymic carcinoid to other organs could lead to devastating consequences.
Qun-yan Xiang, Jin Xu, Ling Liu
doaj   +1 more source