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Carcinoid Syndrome: A Review. [PDF]
Cureus, 2020 Carcinoid syndrome (CS) is a paraneoplastic syndrome caused by the release of serotonin and other substances from well-differentiated neuroendocrine tumors (NETs). The hallmark symptoms of carcinoid syndrome are flushing and diarrhea; atypical signs and symptoms can include wheezing, abdominal pain, valvular heart disease, telangiectasias, pellagra ...
Gade AK, Olariu E, Douthit NT.
europepmc +6 more sources
European Neuroendocrine Tumor Society (ENETS) 2022 Guidance Paper for Carcinoid Syndrome and Carcinoid Heart Disease. [PDF]
J Neuroendocrinol, 2022 Carcinoid Heart Disease Clinic, Department of Cardiology, Royal Free Hospital & University College London, London, UK Department of Internal Medicine, Section of Endocrinology, ENETS Center of Excellence, Erasmus MC and Erasmus Cancer Institute ...
Grozinsky-Glasberg S +13 more
europepmc +2 more sources
Carcinoid syndrome: update on the pathophysiology and treatment
Clinics, 2018 Approximately 30-40% of patients with well-differentiated neuroendocrine tumors present with carcinoid syndrome, which is a paraneoplastic syndrome associated with the secretion of several humoral factors.
Anezka C. Rubin de Celis Ferrari +2 more
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Update on Pathophysiology, Treatment, and Complications of Carcinoid Syndrome. [PDF]
J Oncol, 2020 Carcinoid syndrome (CS) develops in patients with hormone-producing neuroendocrine neoplasms (NENs) when hormones reach a significant level in the systemic circulation. The classical symptoms of carcinoid syndrome are flushing, diarrhoea, abdominal pain,
Clement D, Ramage J, Srirajaskanthan R.
europepmc +2 more sources
J Clin Endocrinol Metab, 2021 Context Peptide receptor radionuclide therapy (PRRT) with [Lutetium-177-DOTA0-Tyr3]octreotate (177Lu-DOTATATE) results in an increase of progression-free survival and quality of life in patients with progressive, well-differentiated neuroendocrine ...
Zandee WT +6 more
europepmc +2 more sources
Serotonin and the carcinoid syndrome [PDF]
Canadian Anaesthetists’ Society Journal, 1959 A brief description of some of the main physiological actions of serotonin has been given. Their clinical implications, especially where they pertain to the field of anaesthesia, are presented in some detail. The malignant carcinoid syndrome is discussed and some of the problems which may confront the anaesthesiologist in dealing with patients ...
W. Philip G. Jones
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The role of serotonin inhibition within the treatment of carcinoid syndrome [PDF]
Endocrine Oncology, 2023 Carcinoid syndrome is the most frequent hormonal complication associated with neuroendocrine neoplasms. It was first reported in 1954, and the classical symptoms are diarrhoea, flushing and abdominal pain.
Joel George +3 more
doaj +2 more sources
Endobronchial Carcinoid and Concurrent Carcinoid Syndrome in an Adolescent Female
Case Reports in Pediatrics, 2016 Endobronchial carcinoid tumors are the most common intrabronchial tumors in children and adolescents. Common signs and symptoms include persistent cough and wheezing not responsive to bronchodilators, hemoptysis, and recurrent fever.
Jonathan D. Cogen +2 more
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Duodenal carcinoid with carcinoid syndrome [PDF]
BMJ Case Reports, 2014 Carcinoid tumours are uncommon well-differentiated neuroendocrine tumours. Primary duodenal carcinoids account for less than 2% of all gastrointestinal carcinoids. Duodenal carcinoids are seldom associated with carcinoid syndrome. We report a rare case of duodenal carcinoid presenting as a carcinoid syndrome in a middle-aged man with upper abdominal ...
Kamesh Konchada +3 more
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Management of Diarrhea in Patients With Carcinoid Syndrome. [PDF]
Pancreas, 2019 Neuroendocrine tumors (NETs) arise from enterochromaffin cells found in neuroendocrine tissues, with most occurring in the gastrointestinal tract. The global incidence of NETs has increased in the past 15 years, likely due to better diagnostic methods ...
Naraev BG +5 more
europepmc +2 more sources