Results 1 to 10 of about 76,206 (274)
Somatostatin and Somatostatin Receptors: From Signaling to Clinical Applications in Neuroendocrine Neoplasms [PDF]
Biomedicines, 2021 Neuroendocrine neoplasms (NENs) are heterogeneous neoplasms which arise from neuroendocrine cells that are distributed widely throughout the body. Although heterogenous, many of them share their ability to overexpress somatostatin receptors (SSTR) on ...
Maria Isabel del Olmo-Garcia +5 more
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eLife, 2022 Somatostatin is a peptide hormone that regulates endocrine systems by binding to G-protein-coupled somatostatin receptors. Somatostatin receptor 2 (SSTR2) is a human somatostatin receptor and is highly implicated in hormone disorders, cancers, and ...
Yunseok Heo +8 more
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European Journal of Medical Research, 2023 Purpose To evaluate the effect of postoperative utilization of somatostatin after definitive surgery for duodenal fistula (DF) in preventing a recurrence.
Weiliang Tian +5 more
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Frontiers in Endocrinology, 2021 Neuroendocrine tumors overexpress somatostatin receptors, which serve as important and unique therapeutic targets for well-differentiated advanced disease.
Mayank Patel +5 more
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Somatostatin receptors in congenital hyperinsulinism: Biology to bedside
Frontiers in Endocrinology, 2022 Congenital hyperinsulinism (CHI), although a rare disease, is an important cause of severe hypoglycemia in early infancy and childhood, causing preventable morbidity and mortality.
Mirjam E. van Albada +4 more
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Current diagnosis and treatment of acute pancreatitis in China: a real-world, multicenter study
BMC Gastroenterology, 2021 Background Efficacy of pancreatic enzyme inhibitors in acute pancreatitis (AP) is unclear in China. Aims We aimed to present the current status of AP and evaluate the efficacy of pancreatic enzyme inhibitors in a larger population in China.
Chuandong Sun +3 more
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Age-dependent patterns of somatostatinergic neurons in sympathetic paravertebral ganglia
Сеченовский вестник, 2023 Aim. We aimed to determine the content of neurons expressing somatostatin (SST) and their colocalization with cells expressing tyrosine hydroxylase (TH) and neuropeptide Y (NPY) in the cranial cervical ganglion (CCG) and celiac plexus in rats ...
A. I. Emanuilov +3 more
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Role of somatostatin receptor-2 in gentamicin-induced auditory hair cell loss in the Mammalian inner ear. [PDF]
PLoS ONE, 2014 Hair cells and spiral ganglion neurons of the mammalian auditory system do not regenerate, and their loss leads to irreversible hearing loss. Aminoglycosides induce auditory hair cell death in vitro, and evidence suggests that phosphatidylinositol-3 ...
Yves Brand +7 more
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Somatostatin receptor expression in parathyroid neoplasms
Endocrine Connections, 2019 Introduction: Parathyroid carcinoma represents a rare cause of primary hyperparathyroidism. Distinguishing carcinoma from the benign tumors underlying primary hyperparathyroidism remains challenging.
Sara Storvall +6 more
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Gastroenterologìa, 2022 Background. The study of clinical features, factors and levels of various biologically active substances that may play an important role in the pathogenetic mechanism of gastroesophageal reflux disease (GERD) in combination with degenerative-dystrophic ...
Ye.S. Szircsak, S.A. Tsoka, Ya.F. Filak
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