Results 21 to 30 of about 76,206 (274)

[Somatostatin receptor scintigraphy in a patient with myocarditis] [Miyokarditli bir hastada somatostatin reseptör sintigrafisi] [PDF]

open access: yes, 2021
We report a case of myocarditis imaged with technetium-99m octreotide cardiac single-photon emission computed tomography which showed diffuse uptake in the myocardium, indicating inflammatory reaction to myocardial damage.
Dehdar, F   +4 more
core  

Astrocytes Modulate Somatostatin Interneuron Signaling in the Visual Cortex

open access: yesCells, 2022
At glutamatergic synapses, astrocytes respond to the neurotransmitter glutamate with intracellular Ca2+ elevations and the release of gliotransmitters that modulate synaptic transmission.
Vanessa Jorge Henriques   +3 more
doaj   +1 more source

PET Imaging of Perceptual Learning-Induced Changes in the Aged Rodent Cholinergic System

open access: yesFrontiers in Neuroscience, 2020
The cholinergic system enhances attention and gates plasticity, making it a major regulator of adult learning. With aging, however, progressive degeneration of the cholinergic system impairs both the acquisition of new skills and functional recovery ...
J. Miguel Cisneros-Franco   +16 more
doaj   +1 more source

Efficacy and Safety of Nasal Immunisation with Somatostatin DNA Vaccine for Growth Promotion in Fattening Pigs

open access: yesAnimals, 2022
This study aimed to evaluate the efficacy and safety of the SS DNA vaccine on growing pigs. Randomly, 147 pigs were divided into four groups, treatment 1 (T1, 3 × 109 CFU/mL, n = 39), T2 (3 × 108 CFU/mL, n = 35), T3 (3 × 107 CFU/mL, n = 35) and control ...
Chao Chen   +5 more
doaj   +1 more source

Somatostatin and somatostatin receptors in Cushing's disease [PDF]

open access: yesMolecular and Cellular Endocrinology, 2008
Cushing's disease is caused by an ACTH secreting pituitary adenoma. Surgery is the treatment of choice and cure rates between 60 and 90% are reported. For patients in which surgery fails, effective medical treatment options are needed. Somatostatin (SS) receptors (sst) are expressed on normal and tumoral corticotroph cells.
openaire   +4 more sources

Long Acting Somatostatin Analogue: Clinical Potential for Gastrointestinal Disease

open access: yesCanadian Journal of Gastroenterology, 1989
Name somatostatin is found throughout the gastrointestinal tract and has a wide variety of biological actions. Nevertheless, its short biological half-life and limited stability necessitate its use via continuous parenteral infusion and, thus, limits its
Richard N. Fedorak
doaj   +1 more source

Somatostatin and Somatostatin Receptors in Tumour Biology

open access: yesInternational Journal of Molecular Sciences, 2023
Somatostatin (SST), a growth hormone inhibitory peptide, is expressed in endocrine and non-endocrine tissues, immune cells and the central nervous system (CNS). Post-release from secretory or immune cells, the first most appreciated role that SST exhibits is the antiproliferative effect in target tissue that served as a potential therapeutic ...
openaire   +2 more sources

π‐Extended COUPY Fluorophores for Targeted Near‐Infrared Fluorescence and Lifetime Imaging in Live Cells

open access: yesAngewandte Chemie, EarlyView.
π‐Extended COUPY dyes, obtained by vinylogation of coumarin‐based COUPY scaffolds, shift absorption, and emission deep into the NIR region while preserving compactness and synthetic accessibility. These bright, photostable dyes enable live‐cell imaging, FLIM, and site‐specific peptide conjugation, offering a modular platform for targeted bioimaging and
Diego Abad‐Montero   +11 more
wiley   +2 more sources

Contribution of liver nerves, glucagon, and adrenaline to the glycaemic response to exercise in rats [PDF]

open access: yes, 1994
The contribution of hepatic sympathetic innervation, glucagon and adrenaline to the glycaemic response to exercise was investigated in rats. Hepatically denervated (LDX) or sham operated (SHAM) rats with permanent catheters were therefore submitted to ...
B. AHRÉN   +30 more
core   +1 more source

19F NMR spectroscopy monitors ligand binding to recombinantly fluorine-labelled b'x from human protein disulphide isomerase (hPDI) [PDF]

open access: yes, 2014
We report a protein-observe (19)F NMR-based ligand titration binding study of human PDI b'x with ?-somatostatin that also emphasises the need to optimise recombinant protein fluorination when using 5- or 6-fluoroindole.
Doko, Denisa   +5 more
core   +1 more source

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