Results 1 to 10 of about 45,557 (210)
Parvalbumin and parvalbumin chandelier interneurons in autism and other psychiatric disorders
Frontiers in Psychiatry, 2022 Parvalbumin (PV) is a calcium binding protein expressed by inhibitory fast-spiking interneurons in the cerebral cortex. By generating a fast stream of action potentials, PV+ interneurons provide a quick and stable inhibitory input to pyramidal neurons and contribute to the generation of gamma oscillations in the cortex.
Pablo Juarez +4 more
exaly +4 more sources
Biomolecules, 2022 Parvalbumin (PA) is a small, acidic, mostly cytosolic Ca2+-binding protein of the EF-hand superfamily. Structural and physical properties of PA are well studied but recently two highly conserved structural motifs consisting of three amino acids each (clusters I and II), which contribute to the hydrophobic core of the EF-hand domains, have been revealed.
Vladimir Uversky +2 more
exaly +5 more sources
Reduction in parvalbumin expression not loss of the parvalbumin-expressing GABA interneuron subpopulation in genetic parvalbumin and shank mouse models of autism [PDF]
Molecular Brain, 2016 A reduction of the number of parvalbumin (PV)-immunoreactive (PV(+)) GABAergic interneurons or a decrease in PV immunoreactivity was reported in several mouse models of autism spectrum disorders (ASD). This includes Shank mutant mice, with SHANK being one of the most important gene families mutated in human ASD.
Markus Wöhr +2 more
exaly +6 more sources
Foods, 2022 This study was aimed to investigate the structural and immunological properties of parvalbumin from mandarin fish during the Maillard reaction. The microwave-assisted the Maillard reaction was optimized by orthogonal designed experiments.
Jingjing Tai +8 more
doaj +1 more source
Evolution of the Parvalbumin Genes in Teleost Fishes after the Whole-Genome Duplication
Fishes, 2021 Parvalbumin is considered a major fish allergen. Here, we report the molecular evolution of the parvalbumin genes in bony fishes based on 19 whole genomes and 70 transcriptomes.
Subham Mukherjee +5 more
doaj +1 more source
Parvalbumin Role in Epilepsy and Psychiatric Comorbidities: From Mechanism to Intervention
Frontiers in Integrative Neuroscience, 2022 Parvalbumin is a calcium-binding protein present in inhibitory interneurons that play an essential role in regulating many physiological processes, such as intracellular signaling and synaptic transmission.
Lívea Dornela Godoy +4 more
doaj +1 more source
Quercetin attenuates the reduction of parvalbumin in middle cerebral artery occlusion animal model
Laboratory Animal Research, 2021 Background Calcium is a critical factor involved in modulation of essential cellular functions. Parvalbumin is a calcium buffering protein that regulates intracellular calcium concentrations.
Dong-Ju Park +3 more
doaj +1 more source
BACHD Mice Recapitulate the Striatal Parvalbuminergic Interneuron Loss Found in Huntington’s Disease
Frontiers in Neuroanatomy, 2021 Huntington’s disease (HD) is a dominantly inherited, adult-onset neurodegenerative disease characterized by motor, psychiatric, and cognitive abnormalities.
Vyshnavi Rallapalle +4 more
doaj +1 more source
Densities and numbers of calbindin and parvalbumin positive neurons across the rat and mouse brain
iScience, 2021 Summary: The calcium-binding proteins parvalbumin and calbindin are expressed in neuronal populations regulating brain networks involved in spatial navigation, memory processes, and social interactions.
Ingvild E. Bjerke +6 more
doaj +1 more source
Binding of Acrylonitrile to Parvalbumin [PDF]
Toxicological Sciences, 1996 A previous study has shown that acrylonitrile (ACN) has a long half-life in rainbow trout muscle and that [14C]ACN appears to be bound to a 10,000-Da protein in muscle. The labeled protein was purified from muscle of trout exposed to [14C]ACN, separated on 20% SDS-PAGE, and digested for amino acid analysis and sequence analysis. These studies indicated
J J, Lech +4 more
openaire +2 more sources