Results 41 to 50 of about 45,557 (210)
Advanced Science, EarlyView.Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou +10 more
wiley +1 more source
Frontiers in Cell and Developmental Biology, 2020 Physical exercise can alleviate some of the schizophrenia symptoms in patients, the mechanisms, however, are still unclear. To investigate whether the GABAergic interneuron involved in the therapeutic effect of treadmill running on schizophrenia, the ...
Yandong Yi +5 more
doaj +1 more source
Advanced Science, EarlyView.FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni +17 more
wiley +1 more source
Post-mortem human brain analysis of the ventral pallidum in alcohol use disorder
Addiction NeuroscienceObjective: Alcohol use disorder (AUD) is characterised by cycles of alcohol misuse, abstinence, and relapse. The neurobiology of AUD strongly implicates the role of the ventral pallidum (VP) in a variety of drugs of abuse, including alcohol. Pre-clinical
Ameer Elena Rasool +4 more
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The Anatomical Record, EarlyView.Abstract The globus pallidus (GP), a subcortical structure within the basal ganglia, plays a crucial role in modulating cortico‐subcortical circuits related to motor control and associative/limbic functions. However, the cytoarchitectonic and neurochemical organization of this structure remains poorly characterized in naturally existing wild‐type ...
Lavínnya Yáskara de Aquino Matoso +10 more
wiley +1 more source
Frontiers in Neuroanatomy, 2012 Previous research has suggested that the three physiologically-defined relay cell types in mammalian lateral geniculate nucleus (LGN) – called parvocellular (P), magnocellular (M), and koniocellular (K) cells in primates and X, Y, and W cells in other ...
Daniel L Felch, Stephen D Van Hooser
doaj +1 more source
Functional and Molecular Analysis of Proprioceptive Sensory Neuron Excitability in Mice
Frontiers in Molecular Neuroscience, 2020 Neurons located in dorsal root ganglia (DRG) are crucial for transmitting peripheral sensations such as proprioception, touch, temperature, and nociception to the spinal cord before propagating these signals to higher brain structures.
Jessica F. Madden +16 more
doaj +1 more source
On the importance of including both sexes in animal studies – insights from home‐cage monitoring
Biological Reviews, EarlyView.ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater +12 more
wiley +1 more source
Subfield-specific interneuron circuits govern the hippocampal response to novelty in male mice
Nature CommunicationsThe hippocampus is the brain’s center for episodic memories. Its subregions, the dentate gyrus and CA1-3, are differentially involved in memory encoding and recall. Hippocampal principal cells represent episodic features like movement, space, and context,
Thomas Hainmueller +3 more
doaj +1 more source
SAT1, a glutamine transporter, is preferentially expressed in GABAergic neurons
Frontiers in Neuroanatomy, 2010 Subsets of GABAergic neurons are able to maintain high frequency discharge patterns, which requires efficient replenishment of the releasable pool of GABA.
Tom Tallak Solbu +8 more
doaj +1 more source