Results 61 to 70 of about 51,758 (256)

Functional and Molecular Analysis of Proprioceptive Sensory Neuron Excitability in Mice

Frontiers in Molecular Neuroscience, 2020
Neurons located in dorsal root ganglia (DRG) are crucial for transmitting peripheral sensations such as proprioception, touch, temperature, and nociception to the spinal cord before propagating these signals to higher brain structures.
Jessica F. Madden, Jessica F. Madden, Olivia C. Davis, Kieran A. Boyle, Jacqueline A. Iredale, Jacqueline A. Iredale, Tyler J. Browne, Tyler J. Browne, Robert J. Callister, Robert J. Callister, Douglas W. Smith, Douglas W. Smith, Phillip Jobling, Phillip Jobling, David I. Hughes, Brett A. Graham, Brett A. Graham   +16 more
doaj   +1 more source

WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy

Epilepsia, EarlyView.
Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara, Erwin A. van Vliet, Alessia Romagnolo, Kevin Staley, Kyle P. Lillis, Chris Dulla, David C. Henshall, Katja Kobow   +7 more
wiley   +1 more source

SAT1, a glutamine transporter, is preferentially expressed in GABAergic neurons

Frontiers in Neuroanatomy, 2010
Subsets of GABAergic neurons are able to maintain high frequency discharge patterns, which requires efficient replenishment of the releasable pool of GABA.
Tom Tallak Solbu, Tom Tallak Solbu, Mona Bjørkmo, Mona Bjørkmo, Paul Berghuis, Tibor Harkany, Tibor Harkany, Farrukh A Chaudhry, Farrukh A Chaudhry   +8 more
doaj   +1 more source

Miro1-dependent Mitochondrial Dynamics in Parvalbumin Interneurons [PDF]

, 2018
Parvalbumin interneurons are fast-spiking inhibitory cells that have been implicated in the generation of rhythmic network activity in the γ-frequency band (30-80Hz) by coordinating principal cell activity.
Kontou, Georgina
core  

Co-localization between GAD67, parvalbumin, and calretinin.

, 2012
Top panel: the images of GAD67, parvalbumin, and calretinin were pseudocolored into green, red, and purple respectively. Bottom panel: the three images were superimposed together. Arrow 1: calretinin positive neuron. Arrow 2: GAD67 positive neuron. Arrow
Virawudh Soontornniyomkij (182426), Baohu Ji (182429), MinJung Kim (5649019), Xianjin Zhou (182433)   +3 more
core   +1 more source

Pyruvate dehydrogenase autoantibodies in autoantibody‐negative patients with seizures are associated with reduced pyruvate dehydrogenase activity

Epilepsia, EarlyView.
Abstract Objective We investigated the presence and potential functional relevance of antimitochondrial autoantibodies in patients suspicious for autoimmune encephalitis (AIE) associated with psychiatric symptoms and/or seizures, who were negative for known antineuronal autoantibodies.
Annika Breuer, Chiara A. Hummel, Tobias Baumgartner, Juliane L. Berns, Afaf Milad Said, Isabel Bünger, Susanne Schoch, Gábor Zsurka, Harald Prüss, Wolfram S. Kunz, Rainer Surges, Albert J. Becker, Julika Pitsch   +12 more
wiley   +1 more source

Mapping alterations in the local synchrony of the cerebral cortex in schizophrenia

European Psychiatry, 2023
Background Observations from different fields of research coincide in indicating that a defective gamma-aminobutyric acid (GABA) interneuron system may be among the primary factors accounting for the varied clinical expression of schizophrenia.
Jesus Pujol, Nuria Pujol, Anna Mané, Gerard Martínez-Vilavella, Joan Deus, Víctor Pérez-Sola, Laura Blanco-Hinojo   +6 more
doaj   +1 more source

Presentation_1_Oncomodulin: The Enigmatic Parvalbumin Protein.pdf

, 2019
EF-hand Ca2+-binding protein family members, α- and β-parvalbumins have been studied for decades. Yet, considerable information is lacking distinguishing functional differences between mammalian α-parvalbumin (PVALB) and oncomodulin (OCM), a branded β ...
Dwayne D. Simmons (7477862), Leslie K. Climer (7116149), Andrew M. Cox (7477859), Timothy J. Reynolds (2095636)   +3 more
core   +1 more source

Compensatory rearrangement of parvalbumin interneuron voltage‐gated sodium channel subunits in a mouse model of Dravet syndrome

Epilepsia, EarlyView.
Abstract Heterozygous loss‐of‐function variants in the gene SCN1A, which encodes the voltage‐gated sodium channel (VGSC) pore‐forming (α) subunit NaV1.1, lead to a spectrum of neurological disease, including Dravet syndrome. NaV1.1 is prominently expressed at the proximal portion of the axon initial segment (AIS) of fast‐spiking γ‐aminobutyric ...
Ania K. Dabrowski, Ala Somarowthu, Sophie R. Liebergall, Damaris N. Lorenzo, Ethan M. Goldberg   +4 more
wiley   +1 more source

Age-related neurochemical changes in the rhesus macaque inferior colliculus.

Frontiers in Aging Neuroscience, 2014
Age-related hearing loss (ARHL) is marked by audiometric hearing deficits that propagate along the auditory pathway. Neurochemical changes as a function of aging have also been identified in neurons along the auditory pathway in both rodents and ...
James eEngle, James eEngle, James eEngle, Daniel T Gray, Heather eTurner, Julia B Udell, Gregg H Recanzone   +6 more
doaj   +1 more source