Results 1 to 10 of about 57,978 (299)
Contrasting roles of axonal (pyramidal cell) and dendritic (interneuron) electrical coupling in the generation of neuronal network oscillations [PDF]
Electrical coupling between pyramidal cell axons, and between interneuron dendrites, have both been described in the hippocampus. What are the functional roles of the two types of coupling?
Bibbig, A. +7 more
core +2 more sources
Interneurons are critical for proper neural network function and can activate Ca2+ signaling in astrocytes. However, the impact of the interneuron-astrocyte signaling into neuronal network operation remains unknown.
Gertrudis Perea +18 more
doaj +1 more source
Cortical interneurons establish inhibitory microcircuits throughout the neocortex and their dysfunction has been implicated in epilepsy and neuropsychiatric diseases.
Matthieu Genestine +14 more
doaj +1 more source
New insights into the classification and nomenclature of cortical GABAergic interneurons. [PDF]
A systematic classification and accepted nomenclature of neuron types is much needed but is currently lacking. This article describes a possible taxonomical solution for classifying GABAergic interneurons of the cerebral cortex based on a novel, web ...
A Karagiannis +82 more
core +3 more sources
Application of cluster analysis in morphological characteristics of neurons
Base on the data for three dimensional (3D) coordinate of 49 neurons, 16 morphological parameters were obtained by calculation. According to the factor analysis of the morphological parameters, three major characteristics, including dimension, degree of ...
ZHANG Jing +5 more
doaj +1 more source
Modifying PCDH19 levels affects cortical interneuron migration
PCDH19 is a transmembrane protein and member of the protocadherin family. It is encoded by the X-chromosome and more than 200 mutations have been linked to the neurodevelopmental PCDH-clustering epilepsy (PCDH19-CE) syndrome.
Anna Pancho +20 more
doaj +1 more source
The cellular and synaptic architecture of the mechanosensory dorsal horn [PDF]
The deep dorsal horn is a poorly characterized spinal cord region implicated in processing low-threshold mechanoreceptor (LTMR) information. We report an array of mouse genetic tools for defining neuronal components and functions of the dorsal horn LTMR ...
Abraira +80 more
core +1 more source
The mouse primary visual cortex (V1) has become an important brain area for exploring how neural circuits process information. Optogenetic tools have helped to outline the connectivity of a local V1 circuit comprising excitatory pyramidal neurons and ...
Tony G. J. Ingram +2 more
doaj +1 more source
Medial Ganglionic Eminence Progenitors Transplanted into Hippocampus Integrate in a Functional and Subtype-Appropriate Manner. [PDF]
Medial ganglionic eminence (MGE) transplantation rescues disease phenotypes in various preclinical models with interneuron deficiency or dysfunction, including epilepsy.
Baraban, Scott C, Hsieh, Jui-Yi
core +1 more source
GABAergic interneuron dysfunction has been implicated in temporal lobe epilepsy (TLE), autism, and schizophrenia. Inhibitory interneuron progenitors transplanted into the hippocampus of rodents with TLE provide varying degrees of seizure suppression.
Nickesha C. Anderson +11 more
doaj +1 more source

