Results 31 to 40 of about 57,978 (299)
Anticipated Synchronization in a Biologically Plausible Model of Neuronal Motifs [PDF]
, 2011 Two identical autonomous dynamical systems coupled in a master-slave configuration can exhibit anticipated synchronization (AS) if the slave also receives a delayed negative self-feedback.
Carelli, Pedro V. +3 more
core +2 more sources
Cell Reports, 2016 Mitochondrial dysfunction has been increasingly linked to neurodevelopmental disorders such as intellectual disability, childhood epilepsy, and autism spectrum disorder, conditions also associated with cortical GABAergic interneuron dysfunction. Although
Erika G. Lin-Hendel +4 more
doaj +1 more source
Single-cell RNA sequencing identifies distinct mouse medial ganglionic eminence cell types. [PDF]
, 2017 Many subtypes of cortical interneurons (CINs) are found in adult mouse cortices, but the mechanism generating their diversity remains elusive. We performed single-cell RNA sequencing on the mouse embryonic medial ganglionic eminence (MGE), the major ...
Chen, Ying-Jiun J +7 more
core +1 more source
GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models. [PDF]
, 2020 NMDA receptors (NMDARs) play subunit-specific roles in synaptic function and are implicated in neuropsychiatric and neurodegenerative disorders. However, the in vivo consequences and therapeutic potential of pharmacologically enhancing NMDAR function via
Chan, Connie +25 more
core +1 more source
Cortical interneurons in autism
Nature Neuroscience, 2021 The mechanistic underpinnings of autism remain a subject of debate and controversy. Why do individuals with autism share an overlapping set of atypical behaviors and symptoms, despite having different genetic and environmental risk factors? A major challenge in developing new therapies for autism has been the inability to identify convergent neural ...
Anis Contractor +2 more
openaire +4 more sources
Membrane resonance enables stable and robust gamma oscillations [PDF]
, 2012 Neuronal mechanisms underlying beta/gamma oscillations (20-80 Hz) are not completely understood. Here, we show that in vivo beta/gamma oscillations in the cat visual cortex sometimes exhibit remarkably stable frequency even when inputs fluctuate ...
Moca, Vasile V. +3 more
core +1 more source
STAR Protocols, 2021 Summary: Interneuron migration involves repetitive cycles of pausing and motion that include nucleokinesis and dynamic branching of the leading process.
Fanny Lepiemme +2 more
doaj +1 more source
Inhibitory synchrony as a mechanism for attentional gain modulation [PDF]
, 2004 Recordings from area V4 of monkeys have revealed that when the focus of attention is on a visual stimulus within the receptive field of a cortical neuron, two distinct changes can occur: The firing rate of the neuron can change and there can be an ...
Fellous, Jean-Marc +4 more
core +5 more sources
Interneurons Scratch an Itch [PDF]
Neuron, 2014 Itch is immensely frustrating. Most studies focus on the cause of itch. In this issue of Neuron, Kardon et al. (2014) find that itch can be modulated by inhibitory neurons that produce dynorphin, an endogenous agonist of κ-opioid receptors.
Pereira, Paula Juliana Seadi +1 more
openaire +2 more sources
Cortical control of chandelier cells in neural codes
Frontiers in Cellular Neuroscience, 2022 Various cortical functions arise from the dynamic interplay of excitation and inhibition. GABAergic interneurons that mediate synaptic inhibition display significant diversity in cell morphology, electrophysiology, plasticity rule, and connectivity ...
Kanghoon Jung +2 more
doaj +1 more source