Results 41 to 50 of about 57,978 (299)

Dedicated hippocampal inhibitory networks for locomotion and immobility [PDF]

, 2017
Network activity is strongly tied to animal movement; however, hippocampal circuits selectively engaged during locomotion or immobility remain poorly characterized.
Arriaga, Moises, Han, Edward B
core   +2 more sources

Aberrant location of inhibitory synaptic marker proteins in the hippocampus of dystrophin-deficient mice [PDF]

, 2014
Duchenne muscular dystrophy (DMD) is a neuromuscular disease that arises from mutations in the dystrophin-encoding gene. Apart from muscle pathology, cognitive impairment, primarily of developmental origin, is also a significant component of the disorder.
Gorecki, Dariusz C., Krasowska, Elzbieta, Swinny, Jerome D., Zablocki, Krzysztof   +3 more
core   +7 more sources

The Chromatin Environment Around Interneuron Genes in Oligodendrocyte Precursor Cells and Their Potential for Interneuron Reprograming

Frontiers in Neuroscience, 2019
Oligodendrocyte precursor cells (OPCs), also known as NG2 glia, arise from neural progenitor cells in the embryonic ganglionic eminences that also generate inhibitory neurons.
Linda L. Boshans, Linda L. Boshans, Daniel C. Factor, Vijender Singh, Jia Liu, Chuntao Zhao, Ion Mandoiu, Q. Richard Lu, Patrizia Casaccia, Paul J. Tesar, Akiko Nishiyama, Akiko Nishiyama, Akiko Nishiyama   +12 more
doaj   +1 more source

Structured inhibitory activity dynamics in new virtual environments

eLife, 2019
Inhibition plays a powerful role in regulating network excitation and plasticity; however, the activity of defined interneuron types during spatial exploration remain poorly understood.
Moises Arriaga, Edward B Han
doaj   +1 more source

Encoding of Tactile Stimuli by Mechanoreceptors and Interneurons of the Medicinal Leech [PDF]

, 2016
For many animals processing of tactile information is a crucial task in behavioral contexts like exploration, foraging, and stimulus avoidance. The leech, having infrequent access to food, developed an energy efficient reaction to tactile stimuli ...
Fathiazar, Elham, Hilgen, Gerrit, Kretzberg, Jutta, Pirschel, Friederice   +3 more
core   +4 more sources

IGF-1 impacts neocortical interneuron connectivity in epileptic spasm generation and resolution

Neurotherapeutics
Little is known about the mechanisms that generate epileptic spasms following perinatal brain injury. Recent studies have implicated reduced levels of Insulin-like Growth Factor 1 (IGF-1) in these patients’ brains.
Carlos J. Ballester-Rosado, John T. Le, Trang T. Lam, Anne E. Anderson, James D. Frost, Jr., John W. Swann   +5 more
doaj   +1 more source

Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk

Nature Communications, 2020
Interneuron subtypes have distinct properties and spatial distributions. Here, the authors show that the molecular-genetic basis of cortical resting-state brain function is shaped by distributions of interneuron-related transcripts and may capture ...
Kevin M. Anderson, Meghan A. Collins, Rowena Chin, Tian Ge, Monica D. Rosenberg, Avram J. Holmes   +5 more
doaj   +1 more source

Identifying functional populations among the interneurons in laminae I-III of the spinal dorsal horn [PDF]

, 2017
The spinal dorsal horn receives input from primary afferent axons, which terminate in a modality-specific fashion in different laminae. The incoming somatosensory information is processed through complex synaptic circuits involving excitatory and ...
Todd, Andrew J.
core   +1 more source

The Interneuron Class Struggle [PDF]

Cell, 2020
In this issue of Cell, Gouwens et al. establish the state of the art for defining inhibitory cell types in the mouse neocortex. By combining morphological, electrophysiological, and transcriptomic features to classify interneurons in the mouse visual cortex, this work provides a roadmap for understanding the diversity of cell types and their functional
Jacob M, Ratliff, Renata, Batista-Brito
openaire   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source