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Hippocampal GABAergic Inhibitory Interneurons. [PDF]
Physiological Reviews, 2017 In the hippocampus GABAergic local circuit inhibitory interneurons represent only ~10–15% of the total neuronal population; however, their remarkable anatomical and physiological diversity allows them to regulate virtually all aspects of cellular and circuit function. Here we provide an overview of the current state of the field of interneuron research,
K. Pelkey +5 more
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Cortical interneurons that specialize in disinhibitory control
Nature, 2013 In the mammalian cerebral cortex the diversity of interneuronal subtypes underlies a division of labour subserving distinct modes of inhibitory control. A unique mode of inhibitory control may be provided by inhibitory neurons that specifically suppress ...
H. Pi +5 more
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Frontiers in Cellular NeuroscienceParvalbumin (PV) interneurons in the dorsal striatum (DS) are fast-spiking GABAergic cells critical for feedforward inhibition and synaptic integration within basal ganglia circuits.
Claire Naon +18 more
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Dichotomous Dynamics in E-I Networks with Strongly and Weakly Intra-connected Inhibitory Neurons
Frontiers in Neural Circuits, 2017 The interconnectivity between excitatory and inhibitory neural networks informs mechanisms by which rhythmic bursts of excitatory activity can be produced in the brain. One such mechanism, Pyramidal Interneuron Network Gamma (PING), relies primarily upon
Scott Rich +2 more
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Cerebral Cortex, 2017 Myelination, the insulating ensheathment of axons by oligodendrocytes, is thought to both optimize signal propagation and provide metabolic support. Despite the well-established physiological importance of myelination to neuronal function, relatively ...
Jeffrey Stedehouder +10 more
semanticscholar +1 more source
CellsNeuroinflammation is increasingly recognized as a major contributor to cognitive and neuropsychiatric dysfunction. The prefrontal cortex (PFC), a key substrate for executive functions and emotional behaviors, appears particularly vulnerable to ...
Maria Concetta Geloso +2 more
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Frontiers in Neuroanatomy, 2019 Myotonic dystrophy (Dystrophia Myotonica; DM) is the most common adult-onset muscular dystrophy and its brain symptoms seriously affect patients’ quality of life. It is caused by extended (CTG)n expansions at 3′-UTR of DMPK gene (DM type 1, DM1) or (CCTG)
Kuang-Yung Lee +6 more
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Frontiers in NeuroscienceTissue clearing and 3D imaging have emerged as powerful techniques to assess the cellular and tissue-level architecture of the spinal cord. With the rapidly increasing variety and complexity of optical tissue clearing techniques, there is a critical need
Andrew W. Buxton +5 more
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The function of Mef2c toward the development of excitatory and inhibitory cortical neurons
Frontiers in Cellular NeuroscienceNeurodevelopmental disorders (NDDs) are caused by abnormal brain development, leading to altered brain function and affecting cognition, learning, self-control, memory, and emotion.
Claire Ward +5 more
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Sleep deprivation following hippocampus-dependent learning downscales synaptic inputs to lateral and medial entorhinal cortex interneurons. [PDF]
SleepBalendran V +4 more
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