Results 11 to 20 of about 118,802 (309)

Hippocampal GABAergic interneurons and memory

open access: yesNeuron, 2023
Summary One of the most captivating questions in neuroscience revolves around the brain’s ability to efficiently and durably capture and store information. It must process continuous input from sensory organs while also encoding memories that can persist
Alexandra Tzilivaki   +2 more
exaly   +2 more sources

Cortical interneurons in autism

open access: yesNature Neuroscience, 2021
The mechanistic underpinnings of autism remain a subject of debate and controversy. Why do individuals with autism share an overlapping set of atypical behaviors and symptoms, despite having different genetic and environmental risk factors?
A. Contractor   +2 more
semanticscholar   +5 more sources

Recruitment of GABAergic Interneurons in the Barrel Cortex during Active Tactile Behavior

open access: yesNeuron, 2019
SUMMARY Neural computation involves diverse types of GABAergic inhibitory interneurons that are integrated with excitatory neurons into precisely structured circuits.
Jianing Yu, Hang Hu, Karel Svoboda
exaly   +2 more sources

Somatostatin-Expressing Interneurons Enable and Maintain Learning-Dependent Sequential Activation of Pyramidal Neurons

open access: yesNeuron, 2019
Summary The activities of neuronal populations exhibit temporal sequences that are thought to mediate spatial navigation, cognitive processing and motor actions.
Avital Adler   +2 more
exaly   +2 more sources

Activity Regulates Cell Death within Cortical Interneurons through a Calcineurin-Dependent Mechanism

open access: yesCell Reports, 2018
We demonstrate that cortical interneurons derived from ventral eminences, including the caudal ganglionic eminence, undergo programmed cell death. Moreover, with the exception of VIP interneurons, this occurs in a manner that is activity-dependent.
Theofanis Karayannis   +2 more
exaly   +2 more sources

Short-Term Amygdala Low-Frequency Stimulation Does not Influence Hippocampal Interneuron Changes Observed in the Pilocarpine Model of Epilepsy

open access: yesCells, 2021
Temporal lobe epilepsy (TLE) is characterized by changes in interneuron numbers in the hippocampus. Deep brain stimulation (DBS) is an emerging tool to treat TLE seizures, although its mechanisms are not fully deciphered. We aimed to depict the effect of
István Mihály   +6 more
doaj   +1 more source

Maternal Deprivation in Rats Decreases the Expression of Interneuron Markers in the Neocortex and Hippocampus

open access: yesFrontiers in Neuroanatomy, 2021
Early life stress has profound effects on the development of the central nervous system. We exposed 9-day-old rat pups to a 24 h maternal deprivation (MD) and sacrificed them as young adults (60-day-old), with the aim to study the effects of early stress
Milan Aksic   +10 more
doaj   +1 more source

Robust perisomatic GABAergic self-innervation inhibits basket cells in the human and mouse supragranular neocortex

open access: yeseLife, 2020
Inhibitory autapses are self-innervating synaptic connections in GABAergic interneurons in the brain. Autapses in neocortical layers have not been systematically investigated, and their function in different mammalian species and specific interneuron ...
Viktor Szegedi   +6 more
doaj   +1 more source

Cell-to-Cell Interactions Mediating Functional Recovery after Stroke

open access: yesCells, 2021
Ischemic damage in brain tissue triggers a cascade of molecular and structural plastic changes, thus influencing a wide range of cell-to-cell interactions.
Claudia Alia   +6 more
doaj   +1 more source

Roles and Transcriptional Responses of Inhibitory Neurons in Learning and Memory

open access: yesFrontiers in Molecular Neuroscience, 2021
Increasing evidence supports a model whereby memories are encoded by sparse ensembles of neurons called engrams, activated during memory encoding and reactivated upon recall.
Corinna Giorgi   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy