Hippocampal GABAergic Inhibitory Interneurons [PDF]
In the hippocampus GABAergic local circuit inhibitory interneurons represent only ~10–15% of the total neuronal population; however, their remarkable anatomical and physiological diversity allows them to regulate virtually all aspects of cellular and circuit function. Here we provide an overview of the current state of the field of interneuron research,
Pelkey, Kenneth A. +5 more
openaire +4 more sources
Medial Ganglionic Eminence Progenitors Transplanted into Hippocampus Integrate in a Functional and Subtype-Appropriate Manner. [PDF]
Medial ganglionic eminence (MGE) transplantation rescues disease phenotypes in various preclinical models with interneuron deficiency or dysfunction, including epilepsy.
Baraban, Scott C, Hsieh, Jui-Yi
core +1 more source
Circuit interactions within the medial entorhinal cortex (MEC) translate movement into a coherent code for spatial location. Entorhinal principal cells are subject to strong lateral inhibition, suggesting that a disinhibitory mechanism may drive their ...
Saishree Badrinarayanan +6 more
doaj +1 more source
New insights into the classification and nomenclature of cortical GABAergic interneurons. [PDF]
A systematic classification and accepted nomenclature of neuron types is much needed but is currently lacking. This article describes a possible taxonomical solution for classifying GABAergic interneurons of the cerebral cortex based on a novel, web ...
A Karagiannis +82 more
core +3 more sources
Mutant huntingtin expression in somatostatin-positive interneurons contributes to neurophysiological and behavioral phenotypes in BACHD mice [PDF]
Jahmel A. Fowler +4 more
doaj +2 more sources
Modeling interneuron-specific (IS) interneurons in hippocampus [PDF]
The hippocampus and cortex have a large diversity in inhibitory interneuron types. These local interneurons exert inhibitory control over neuronal populations in the hippocampus [1]. Although much is known about how hippocampal inhibitory interneurons exert control over pyramidal cells and synchronize local network activity, less is known about how the
Guet-McCreight, Alexandre +3 more
openaire +2 more sources
Interneuron development and dysfunction [PDF]
Understanding excitation and inhibition balance in the brain begins with the tale of two basic types of neurons, glutamatergic projection neurons and GABAergic interneurons. The diversity of cortical interneurons is contributed by multiple origins in the ventral forebrain, various tangential migration routes, and complicated regulations of intrinsic ...
Jiaxin Yang, Xiong Yang, Ke Tang
openaire +2 more sources
Neurochemical characterisation of lamina II inhibitory interneurons that express GFP in the PrP-GFP mouse [PDF]
Background Inhibitory interneurons in the superficial dorsal horn play important roles in modulating sensory transmission, and these roles are thought to be performed by distinct functional populations. We have identified 4 non-overlapping classes among
Garzillo, F. +4 more
core +2 more sources
Higher Network Activity Induced by Tactile Compared to Electrical Stimulation of Leech Mechanoreceptors [PDF]
The tiny ensemble of neurons in the leech ganglion can discriminate the locations of touch stimuli on the skin as precisely as a human fingertip. The leech uses this ability to locally bend the body-wall away from the stimulus. It is assumed that a three-
Fathiazar, Elham +2 more
core +3 more sources
Converting resident glia into functional and subtype-specific neurons in vivo by delivering reprogramming genes directly to the brain provides a step forward toward the possibility of treating brain injuries or diseases.
Maria Pereira +6 more
doaj +1 more source

