Results 11 to 20 of about 83,755 (215)
Co-activation of Selective Nicotinic Acetylcholine Receptor Subtypes Is Required for Neuroprotection against Alzheimer's Disease. [PDF]
Adv Sci (Weinh)ABSTRACT Beta‐amyloid peptide (Aβ)‐induced suppression of hippocampal GABAergic interneuron activity drives hyperexcitability, amyloid pathology, and cognitive impairment in Alzheimer's disease (AD), suggesting that enhancing hippocampal inhibition may be protective.
Lee R, Kim G, Black ER, Kim S.
europepmc +2 more sources
Decoding the Neural Circuit Underlying Context-Cue Association in Retrieval of Morphine Reward Memory. [PDF]
Adv Sci (Weinh)Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Shi Z +8 more
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Reconsidering Control Logic and Translational Interpretation in TNEA-Based Modulation of Hippocampal Oscillations. [PDF]
Adv Sci (Weinh)Advanced Science, EarlyView.
Gong C, Fan AY.
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Stem Cell Reports, 2017 Converting resident glia into functional and subtype-specific neurons in vivo by delivering reprogramming genes directly to the brain provides a step forward toward the possibility of treating brain injuries or diseases.
Maria Pereira +6 more
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Layer 5 Callosal Parvalbumin-Expressing Neurons: A Distinct Functional Group of GABAergic Neurons
Frontiers in Cellular Neuroscience, 2018 Previous studies have shown that parvalbumin-expressing neurons (CC-Parv neurons) connect the two hemispheres of motor and sensory areas via the corpus callosum, and are a functional part of the cortical circuit.
Hector Zurita +2 more
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Frontiers in Neural Circuits, 2021 Prefrontal cortical GABAergic interneurons (INs) and their innervations are essential for the execution of complex behaviors such as working memory, social behavior, and fear expression.
Sha-Sha Yang +4 more
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Gene-Environment Interaction in a Conditional NMDAR-Knockout Model of Schizophrenia
Frontiers in Behavioral Neuroscience, 2019 Interactions between genetic and environmental risk factors take center stage in the pathology of schizophrenia. We assessed if the stressor of reduced environmental enrichment applied in adulthood provokes deficits in the positive, negative or cognitive
Alexei M. Bygrave +6 more
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Spinal Control of Locomotion: Individual Neurons, Their Circuits and Functions
Frontiers in Physiology, 2018 Systematic research on the physiological and anatomical characteristics of spinal cord interneurons along with their functional output has evolved for more than one century.
Marie-Pascale Côté +4 more
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Structural Changes Observed in the Piriform Cortex in a Rat Model of Pre-motor Parkinson’s Disease
Frontiers in Cellular Neuroscience, 2018 Early diagnosis of Parkinson’s disease (PD) offers perhaps, the most promising route to a successful clinical intervention, and the use of an animal model exhibiting symptoms comparable to those observed in PD patients in the early stage of the disease ...
Marco Sancandi +4 more
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Frontiers in Cell and Developmental Biology, 2020 Neural stem cells in the lateral ganglionic eminence (LGE) generate progenitors that migrate through the rostral migratory stream (RMS) to repopulate olfactory bulb (OB) interneurons, but the regulation of this process is poorly defined.
Christopher A. Blackwood +6 more
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