Results 31 to 40 of about 118,802 (309)
Development and functional diversification of cortical interneurons
Neuron, 2018 In the cerebral cortex, GABAergic interneurons have evolved as a highly heterogeneous collection of cell types that are characterized by their unique spatial and temporal capabilities to influence neuronal circuits.
L. Lim, Da Mi, Alfredo Llorca, O. Marín
semanticscholar +1 more source
Interneurons Scratch an Itch [PDF]
Neuron, 2014 Itch is immensely frustrating. Most studies focus on the cause of itch. In this issue of Neuron, Kardon et al. (2014) find that itch can be modulated by inhibitory neurons that produce dynorphin, an endogenous agonist of κ-opioid receptors.
Pereira, Paula Juliana Seadi +1 more
openaire +2 more sources
Front. Neural Circuits, 2018 Elucidating the prefrontal cortical microcircuit has been challenging, given its role in multiple complex behaviors, including working memory, cognitive flexibility, attention, social interaction and emotional regulation.
Brielle R. Ferguson, Wen-Jun Gao
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Layer 5 Callosal Parvalbumin-Expressing Neurons: A Distinct Functional Group of GABAergic Neurons
Frontiers in Cellular Neuroscience, 2018 Previous studies have shown that parvalbumin-expressing neurons (CC-Parv neurons) connect the two hemispheres of motor and sensory areas via the corpus callosum, and are a functional part of the cortical circuit.
Hector Zurita +2 more
doaj +1 more source
Frontiers in Neural Circuits, 2021 Prefrontal cortical GABAergic interneurons (INs) and their innervations are essential for the execution of complex behaviors such as working memory, social behavior, and fear expression.
Sha-Sha Yang +4 more
doaj +1 more source
Nature Neuroscience, 2013 Cortical inhibitory neurons contact each other to form a network of inhibitory synaptic connections. Our knowledge of the connectivity pattern underlying this inhibitory network is, however, still incomplete.
C. Pfeffer +4 more
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Nature Communications, 2020 Inhibitory interneurons orchestrate information flow across the cortex and are implicated in psychiatric illness. Although interneuron classes have unique functional properties and spatial distributions, the influence of interneuron subtypes on brain ...
K. Anderson +5 more
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GABA interneurons are the cellular trigger for ketamine's rapid antidepressant actions.
Journal of Clinical Investigation, 2019 A single sub-anesthetic dose of ketamine, an NMDA receptor (NMDAR) antagonist, produces rapid and sustained antidepressant actions in depressed patients, addressing a major unmet need for the treatment of mood disorders.
Danielle M. Gerhard +11 more
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Three Groups of Interneurons Account for Nearly 100% of Neocortical GABAergic Neurons
Developmental Neurobiology, 2011 An understanding of the diversity of cortical GABAergic interneurons is critical to understand the function of the cerebral cortex. Recent data suggest that neurons expressing three markers, the Ca2+‐binding protein parvalbumin (PV), the neuropeptide ...
B. Rudy +3 more
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Molecular Psychiatry, 2020 Major depressive disorder (MDD) is associated with alterations of GABAergic interneurons, notably somatostatin (Sst) as well as parvalbumin (Pvalb), in cortical brain areas.
M. Fogaça +5 more
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