Results 51 to 60 of about 82,209 (267)

A Sweet Talk: The Molecular Systems of Perineuronal Nets in Controlling Neuronal Communication

open access: yesFrontiers in Integrative Neuroscience, 2017
Perineuronal nets (PNNs) are mesh-like structures, composed of a hierarchical assembly of extracellular matrix molecules in the central nervous system (CNS), ensheathing neurons and regulating plasticity.
Heleen M. van 't Spijker   +2 more
doaj   +1 more source

Reticulospinal inhibition of interneurones

open access: yesThe Journal of Physiology, 1968
1. The effect of electrical stimulation of the brain stem on interneurones in the dorsal horn and intermediary region has been investigated in decerebrate cats after partial transection of the spinal cord.2. Stimuli that effectively depress reflex transmission without giving a primary afferent depolarization inhibit the discharge evoked from the flexor
I, Engberg, A, Lundberg, R W, Ryall
openaire   +3 more sources

Editorial: At the top of the interneuronal pyramid—calretinin expressing cortical interneurons [PDF]

open access: yesFrontiers in Neuroanatomy, 2015
Intracellular protein calretinin (CR) acquired its name based on structural similarity to calbindin D28k and the site of first detection—retina (Rogers, 1987). Soon after this discovery, a basic description of the distribution of CR in rodent brain emerged from the work of several authors (reviewed by Baimbridge et al., 1992; Andressen et al., 1993 ...
Barinka, Filip   +2 more
openaire   +2 more sources

Polydopamine Nanoparticle‐Mediated Precise Near‐Infrared Optical Stimulation for Cognitive Enhancement

open access: yesAdvanced Science, EarlyView.
Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou   +10 more
wiley   +1 more source

Translatome of dorsal striatum parvalbumin interneurons revisited: insights across diverse experimental paradigms

open access: yesFrontiers in Cellular Neuroscience
Parvalbumin (PV) interneurons in the dorsal striatum (DS) are fast-spiking GABAergic cells critical for feedforward inhibition and synaptic integration within basal ganglia circuits.
Claire Naon   +18 more
doaj   +1 more source

Local axonal morphology guides the topography of interneuron myelination in mouse and human neocortex

open access: yeseLife, 2019
GABAergic fast-spiking parvalbumin-positive (PV) interneurons are frequently myelinated in the cerebral cortex. However, the factors governing the topography of cortical interneuron myelination remain incompletely understood.
Jeffrey Stedehouder   +10 more
doaj   +1 more source

Postnatal Migration of Cerebellar Interneurons [PDF]

open access: yesBrain Sciences, 2017
Due to its continuing development after birth, the cerebellum represents a unique model for studying the postnatal orchestration of interneuron migration. The combination of fluorescent labeling and ex/in vivo imaging revealed a cellular highway network within cerebellar cortical layers (the external granular layer, the molecular layer, the Purkinje ...
Galas, Ludovic   +7 more
openaire   +5 more sources

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

open access: yesAdvanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li   +10 more
wiley   +1 more source

Neuroinflammation and Prefrontal Cortical Microcircuits: A Narrative Review of Hints from Experimental Models

open access: yesCells
Neuroinflammation is increasingly recognized as a major contributor to cognitive and neuropsychiatric dysfunction. The prefrontal cortex (PFC), a key substrate for executive functions and emotional behaviors, appears particularly vulnerable to ...
Maria Concetta Geloso   +2 more
doaj   +1 more source

Perineuronal nets control visual input via thalamic recruitment of cortical PV interneurons

open access: yeseLife, 2018
In the neocortex, critical periods (CPs) of plasticity are closed following the accumulation of perineuronal nets (PNNs) around parvalbumin (PV)-positive inhibitory interneurons. However, how PNNs tune cortical function and plasticity is unknown.
Giulia Faini   +7 more
doaj   +1 more source

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