Results 1 to 10 of about 192,251 (301)

On the role of the striatum in response inhibition. [PDF]

open access: yesPLoS ONE, 2010
BACKGROUND: Stopping a manual response requires suppression of the primary motor cortex (M1) and has been linked to activation of the striatum. Here, we test three hypotheses regarding the role of the striatum in stopping: striatum activation during ...
Bram B Zandbelt, Matthijs Vink
doaj   +1 more source

Lack of Autophagy Induction by Lithium Decreases Neuroprotective Effects in the Striatum of Aged Rats

open access: yesPharmaceutics, 2021
The pharmacological modulation of autophagy is considered a promising neuroprotective strategy. While it has been postulated that lithium regulates this cellular process, the age-related effects have not been fully elucidated.
Angelica Jardim Costa   +6 more
doaj   +1 more source

Striatal ZBTB16 Is Associated With Cognitive Deficits in Alzheimer Disease Mice [PDF]

open access: yesInternational Neurourology Journal, 2022
Purpose In Alzheimer disease (AD), brain regions such as the cortex and the hippocampus show abundant amyloid load which correlates with cognitive function decline.
Sangjoon Lee   +4 more
doaj   +1 more source

Effects of prolactin on movement disorders and APOE, GFAP, and PRL receptor gene expression following intracerebral hemorrhage in rats [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2021
Objective(s): Intracerebral hemorrhage (ICH) occurs mostly in the striatum. In ICH, blood prolactin level increases 3-fold. The effects of intracerebroventricular injection (ICV) of prolactin on motor disorders will be investigated. Materials and Methods:
Shiba Yousefvand   +6 more
doaj   +1 more source

Implication of ermCX gene of Corynebacterium striatum in macrolide resistance in Beijing, China

open access: yesBangladesh Journal of Pharmacology, 2013
To study the resistance mechanism of Corynebacterium striatum clinical isolates to macrolide antibiotic, 57 strains of C. striatum clinical isolates were detected by susceptibility testing, PCR amplification and DNA sequencing.
Wei Li, Zheng Zhang
doaj   +1 more source

Altered Cortical-Striatal Network in Patients With Hemifacial Spasm

open access: yesFrontiers in Human Neuroscience, 2021
Objective: Hemifacial spasm (HFS) is a kind of motor disorder, and the striatum plays a significant role in motor function. The purpose of this study was to explore the alterations of the cortical-striatal network in HFS using resting-state functional ...
Wenwen Gao   +14 more
doaj   +1 more source

Dissecting Motor and Cognitive Component Processes of a Finger-Tapping Task With Hybrid Dopamine Positron Emission Tomography and Functional Magnetic Resonance Imaging

open access: yesFrontiers in Human Neuroscience, 2021
Striatal dopamine is involved in facilitation of motor action as well as various cognitive and emotional functions. Positron emission tomography (PET) is the primary imaging method used to investigate dopamine function in humans.
Filip Grill   +14 more
doaj   +1 more source

Dimensionality reduction and recurrence analysis reveal hidden structures of striatal pathological states

open access: yesFrontiers in Systems Neuroscience, 2022
A pipeline is proposed here to describe different features to study brain microcircuits on a histological scale using multi-scale analyses, including the uniform manifold approximation and projection (UMAP) dimensional reduction technique and modularity ...
Miguel Serrano-Reyes   +8 more
doaj   +1 more source

NT-4/5 Exacerbates Free Radical-Induced Neuronal Necrosis in Vitro and in Vivo

open access: yesNeurobiology of Disease, 2000
Neurotrophins render neurons highly vulnerable to certain injuries. We examined the possibility that NT-4/5 would enhance free radical neurotoxicity in vivo as well as in vitro.
Seok J. Won   +6 more
doaj   +1 more source

Adult Neurogenesis and Stroke: A Tale of Two Neurogenic Niches

open access: yesFrontiers in Neuroscience, 2021
In the aftermath of an acute stroke, numerous signaling cascades that reshape the brain both in the perilesional zone as well as in more distal regions are activated.
Mihai Ceanga   +4 more
doaj   +1 more source

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