Results 31 to 40 of about 192,251 (301)

Amphetamine and pseudoephedrine cross-tolerance measured by c-Fos protein expression in brains of chronically treated rats [PDF]

open access: yes, 2008
Background Pseudoephedrine is a drug commonly prescribed as a nasal decongestant and bronchodilator and is also freely available in cold remedies and medications.
Tongjaroenbuangam, W.   +12 more
core   +1 more source

Striatal Volume Increase After Six Weeks of Selective Dopamine D2/3 Receptor Blockade in First-Episode, Antipsychotic-Naïve Schizophrenia Patients

open access: yesFrontiers in Neuroscience, 2020
Patients with chronic schizophrenia often display enlarged striatal volumes, and antipsychotic drugs may contribute via the dopamine D2/3 receptor (D2/3R) blockade.
Helle G. Andersen   +19 more
doaj   +1 more source

Neuronal Replacement as a Tool for Basal Ganglia Circuitry Repair: 40 Years in Perspective

open access: yesFrontiers in Cellular Neuroscience, 2020
The ability of new neurons to promote repair of brain circuitry depends on their capacity to re-establish afferent and efferent connections with the host.
Anders Björklund, Malin Parmar
doaj   +1 more source

The microcircuits of striatum in silico [PDF]

open access: yesProceedings of the National Academy of Sciences, 2020
The basal ganglia play an important role in decision making and selection of action primarily based on input from cortex, thalamus, and the dopamine system. Their main input structure, striatum, is central to this process. It consists of two types of projection neurons, together representing 95% of the neurons, and 5% of interneurons, among which are ...
Hjorth, J. J. Johannes   +11 more
openaire   +3 more sources

Dopamine restores reward prediction errors in old age [PDF]

open access: yes, 2013
Senescence affects the ability to utilize information about the likelihood of rewards for optimal decision-making. Using functional magnetic resonance imaging in humans, we found that healthy older adults had an abnormal signature of expected value ...
Dayan, P.   +32 more
core   +1 more source

Adult-specific Reelin expression alters striatal neuronal organization: implications for neuropsychiatric disorders

open access: yesFrontiers in Cellular Neuroscience, 2023
In addition to neuronal migration, brain development, and adult plasticity, the extracellular matrix protein Reelin has been extensively implicated in human psychiatric disorders such as schizophrenia, bipolar disorder, and autism spectrum disorder ...
Mònica Pardo   +28 more
doaj   +1 more source

Nrsn1-Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic-phase Recovery After Ischemic Stroke. [PDF]

open access: yesAdv Sci (Weinh)
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Zhang R   +18 more
europepmc   +2 more sources

Changes in functional connectivity within the rat striatopallidal axis during global brain activation in vivo [PDF]

open access: yes, 2006
The functional organization of the basal ganglia (BG) is often defined according to one of two opposing schemes. The first proposes multiple, essentially independent channels of information processing.
Sharott, A   +6 more
core   +1 more source

Recurrent inhibitory network among cholinergic inerneurons of the striatum [PDF]

open access: yes, 2008
textThe striatum is the initial input nuclei of the basal ganglia, and it serves as an integral processing center for action selection and sensorimotor learning.
Sullivan, Matthew Alexander
core   +1 more source

Neural Correlates for Intrinsic Motivational Deficits of Schizophrenia; Implications for Therapeutics of Cognitive Impairment

open access: yesFrontiers in Psychiatry, 2018
The ultimate goal of the treatment of schizophrenia is recovery, a notion related to improvement of cognitive and social functioning. Cognitive remediation therapies (CRT), one of the most effective cognition enhancing methods, have been shown to ...
Kazuyoshi Takeda   +7 more
doaj   +1 more source

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