Results 31 to 40 of about 158,988 (311)

Comparison and Functional Genetic Analysis of Striatal Protein Expression Among Diverse Inbred Mouse Strains

Frontiers in Molecular Neuroscience, 2019
C57BL/6J (B6) and DBA/2J (D2) inbred mouse strains are highly variable genetically and differ in a large number of behavioral traits related to striatal function, including depression, anxiety, stress response, and response to drugs of abuse. The genetic
Cory Parks, Francesco Giorgianni, Byron C. Jones, Sarka Beranova-Giorgianni, Bob M. Moore II, Megan K. Mulligan   +5 more
doaj   +1 more source

A Biologically Plausible Architecture of the Striatum to Solve Context-Dependent Reinforcement Learning Tasks

Frontiers in Neural Circuits, 2017
Basal ganglia circuit is an important subcortical system of the brain thought to be responsible for reward-based learning. Striatum, the largest nucleus of the basal ganglia, serves as an input port that maps cortical information. Microanatomical studies
Sabyasachi Shivkumar, Vignesh Muralidharan, V. Srinivasa Chakravarthy   +2 more
doaj   +1 more source

The organization of midbrain projections to the striatum in the primate: Sensorimotor-related striatum versus ventral striatum

Neuroscience, 1994
In order to examine the organization of nigrostriatal projections in the primate, the retrograde tracers Lucifer Yellow conjugated to dextran amines and horseradish peroxidase conjugated to wheatgerm agglutinin were injected into different regions of the dorsolateral and ventral striatum.
E, Lynd-Balta, S N, Haber
openaire   +2 more sources

Comparison of bloodstream infections due to Corynebacterium striatum, MRSA, and MRSE

BMC Infectious Diseases
Background Corynebacterium striatum (C. striatum), a common skin and mucosal colonizer, is increasingly considered as an opportunistic pathogen causing bloodstream infections (BSIs). This study aims to investigate the clinical features and outcomes of C.
Shu-Hua He, Yan Chen, Hong-Li Sun, Shan Li, Shi-Tong Diao, Yi-Fan Wang, Zhuo-Xin He, Li Weng, Jin-Min Peng, Bin Du   +9 more
doaj   +1 more source

Dorsomedial striatum, but not dorsolateral striatum, is necessary for rat category learning

Neurobiology of Learning and Memory, 2023
Categorization is an adaptive cognitive function that allows us to generalize knowledge to novel situations. Converging evidence from neuropsychological, neuroimaging, and neurophysiological studies suggest that categorization is mediated by the basal ganglia; however, there is debate regarding the necessity of each subregion of the basal ganglia and ...
Matthew B. Broschard, Jangjin Kim, Bradley C. Love, John H. Freeman   +3 more
openaire   +3 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Uptake of 18F-AV45 in the Putamen Provides Additional Insights into Alzheimer’s Disease beyond the Cortex

Biomolecules
Cortical uptake in brain amyloid positron emission tomography (PET) is increasingly used for the biological diagnosis of Alzheimer’s disease (AD); however, the clinical and biological relevance of the striatum beyond the cortex in amyloid PET scans ...
Zhengshi Yang, Jefferson W. Kinney, Dietmar Cordes, The Alzheimer’s Disease Neuroimaging Initiative   +3 more
doaj   +1 more source

Noise exposure in early adulthood causes age-dependent and brain region-specific impairments in cognitive function

Frontiers in Neuroscience, 2022
Hearing loss is a chronic health condition that affects millions of people worldwide. In addition to age-related hearing impairment, excessive noise exposure is a leading cause of hearing loss. Beyond the devastating effects of hearing impairment itself,
Salonee V. Patel, Courtney M. DeCarlo, Shae A. Book, Ashley L. Schormans, Shawn N. Whitehead, Brian L. Allman, Sarah H. Hayes   +6 more
doaj   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Dopamine D1 and Glutamate Receptors Co-operate With Brain-Derived Neurotrophic Factor (BDNF) and TrkB to Modulate ERK Signaling in Adult Striatal Slices

Frontiers in Cellular Neuroscience, 2020
In the striatum, the input nucleus of the basal ganglia, the extracellular-signal-regulated kinase (ERK) pathway, necessary for various forms of behavioral plasticity, is triggered by the combined engagement of dopamine D1 and ionotropic glutamate ...
Ilaria Morella, Ilaria Morella, Harriet Hallum, Harriet Hallum, Riccardo Brambilla, Riccardo Brambilla   +5 more
doaj   +1 more source