Results 51 to 60 of about 158,988 (311)

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu, Changgeng Song, Dianwei Wu, Xiaoqian Niu, Jianmin Hao, Lijuan Liu, Xiaogang Kang, Wen Jiang   +7 more
wiley   +1 more source

Hypoxia Disrupted Serotonin Levels in the Prefrontal Cortex and Striatum, Leading to Depression-like Behavior

Biology
Hypoxia can adversely affect multiple organ systems. This study investigated the impact of intermittent hypoxia on serotonin levels and depression-like behaviors across distinct neuroanatomical regions.
Hasan Çalışkan, Koray Hamza Cihan, Seda Koçak, Gözde Karabulut, Erhan Nalçacı   +4 more
doaj   +1 more source

Claustrum Involvement in New Onset Refractory Status Epilepticus: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The claustrum sign is a distinctive neuroimaging finding characterized by bilateral T2/FLAIR hyperintensity of the claustrum, one of the most interconnected regions of the human brain. It was first described in new‐onset refractory status epilepticus (NORSE) and febrile infection–related epilepsy syndrome (FIRES).
Margherita Burani, Lorenzo Muccioli, Giada Giovannini, Niccolò Orlandi, Francesca Bisulli, Stefano Meletti   +5 more
wiley   +1 more source

A neural network model combining the successor representation and actor-critic methods reveals effective biological use of the representation

Frontiers in Computational Neuroscience
In learning goal-directed behavior, state representation is important for adapting to the environment and achieving goals. A predictive state representation called successive representation (SR) has recently attracted attention as a candidate for state ...
Takayuki Tsurumi, Kenji Morita, Kenji Morita   +2 more
doaj   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Characterization of the tyrosine-hydroxylase immunoreactive components of the basal subpallium in sharks—toward an identification of a basal subpallial complex

Frontiers in Neuroanatomy
Comparative studies on the forebrain across different model organisms are necessary to investigate the origin and degree of evolutionary conservation of this brain region and its derivatives. The catshark Scyliorhinus canicula has become a reliable model
Isabel Rodríguez-Moldes, Catalina Sueiro, Iván Carrera, Idoia Quintana-Urzainqui, Eva Candal   +4 more
doaj   +1 more source

Multisensory Integration in the Mouse Striatum [PDF]

Neuron, 2014
The basal ganglia are involved in sensorimotor functions and action selection, both of which require the integration of sensory information. In order to determine how such sensory inputs are integrated, we obtained whole-cell recordings in mouse dorsal striatum during presentation of tactile and visual stimuli.
Ramon Reig, Gilad Silberberg
openaire   +3 more sources

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Depression-associated reductions in putaminal volume are accompanied by a shift from matrix-like to striosome-like structural connectivity

Frontiers in Psychiatry
The striatum is among the most studied brain regions in Major Depressive Disorder (MDD) due to its involvement in reward, motivation, and executive functions.
An N. Tieu, Jeff L. Waugh, Jeff L. Waugh
doaj   +1 more source

Targeting Neuronal Populations of the Striatum [PDF]

Frontiers in Neuroanatomy, 2011
The striatum is critically involved in motor and motivational functions. The dorsal striatum, caudate-putamen, is primarily implicated in motor control and the learning of habits and skills, whereas the ventral striatum, the nucleus accumbens, is essential for motivation and drug reinforcement.
Durieux, Pierre, Schiffmann, Serge N., de Kerchove d'Exaerde, Alban   +2 more
openaire   +4 more sources