Results 11 to 20 of about 158,988 (311)

Altered Cortical-Striatal Network in Patients With Hemifacial Spasm

Frontiers in Human Neuroscience, 2021
Objective: Hemifacial spasm (HFS) is a kind of motor disorder, and the striatum plays a significant role in motor function. The purpose of this study was to explore the alterations of the cortical-striatal network in HFS using resting-state functional ...
Wenwen Gao, Wenwen Gao, Dong Yang, Zhe Zhang, Lei Du, Bing Liu, Jian Liu, Yue Chen, Yige Wang, Xiuxiu Liu, Aocai Yang, Kuan Lv, Jiajia Xue, Guolin Ma, Guolin Ma   +14 more
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The dynamics of striatum circuitry [PDF]

Frontiers in Integrative Neuroscience, 2010
Learning new motor skills is an integral and essential part of our life. Remember the first time riding a bike or learning to ski? After a new skill is acquired, the once daunting task becomes effortless and automatic. How does our brain accomplish such a feat? Which brain systems are involved, and how? A recent article by Yin et al.
openaire   +3 more sources

Dissecting Motor and Cognitive Component Processes of a Finger-Tapping Task With Hybrid Dopamine Positron Emission Tomography and Functional Magnetic Resonance Imaging

Frontiers in Human Neuroscience, 2021
Striatal dopamine is involved in facilitation of motor action as well as various cognitive and emotional functions. Positron emission tomography (PET) is the primary imaging method used to investigate dopamine function in humans.
Filip Grill, Filip Grill, Jarkko Johansson, Jarkko Johansson, Jan Axelsson, Jan Axelsson, Patrik Brynolfsson, Patrik Brynolfsson, Lars Nyberg, Lars Nyberg, Lars Nyberg, Anna Rieckmann, Anna Rieckmann, Anna Rieckmann, Anna Rieckmann   +14 more
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Autophagic bias in the striatum [PDF]

Autophagy, 2020
Macroautophagy/autophagy is implicated in the maintenance of normal neuronal activity through the regulation of synaptic function and plasticity. However, differences in autophagic degradation within different classes of neurons have not been examined.
Irena Pigulevskiy, Ori J. Lieberman, David Sulzer   +2 more
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Dimensionality reduction and recurrence analysis reveal hidden structures of striatal pathological states

Frontiers in Systems Neuroscience, 2022
A pipeline is proposed here to describe different features to study brain microcircuits on a histological scale using multi-scale analyses, including the uniform manifold approximation and projection (UMAP) dimensional reduction technique and modularity ...
Miguel Serrano-Reyes, Miguel Serrano-Reyes, Jesús Esteban Pérez-Ortega, Jesús Esteban Pérez-Ortega, Brisa García-Vilchis, Antonio Laville, Aidán Ortega, Elvira Galarraga, Jose Bargas   +8 more
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NT-4/5 Exacerbates Free Radical-Induced Neuronal Necrosis in Vitro and in Vivo

Neurobiology of Disease, 2000
Neurotrophins render neurons highly vulnerable to certain injuries. We examined the possibility that NT-4/5 would enhance free radical neurotoxicity in vivo as well as in vitro.
Seok J. Won, Eun C. Park, Bo R. Ryu, Hyuk W. Ko, Seonghyang Sohn, Hyuk J. Kwon, Byoung J. Gwag   +6 more
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Adult Neurogenesis and Stroke: A Tale of Two Neurogenic Niches

Frontiers in Neuroscience, 2021
In the aftermath of an acute stroke, numerous signaling cascades that reshape the brain both in the perilesional zone as well as in more distal regions are activated.
Mihai Ceanga, Mihai Ceanga, Mahmoud Dahab, Otto W. Witte, Silke Keiner   +4 more
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Transplantation of neuronal precursors derived from induced pluripotent stem cells into the striatum of rats with the toxin-induced model of Huntington’s disease

Анналы клинической и экспериментальной неврологии, 2017
Introduction.Huntingtons disease (HD) is a severe neurodegenerativedisorder characterized by choreic hyperkinesis, cognitivedecline, behavioral disorders, and progressive neuronal death,mostly in the striatum.
Alla V. Stavrovskaya, Nina G. Yamshchikova, Аrtyem S. Ol'shansky, Eugeniya V. Konovalova, Sergey N. Illarioshkin   +4 more
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Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors

Frontiers in Neurology, 2022
Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases.
Bradley S. Hollidge, Hayley B. Carroll, Randolph Qian, Madison L. Fuller, April R. Giles, Andrew C. Mercer, Olivier Danos, Ye Liu, Joseph T. Bruder, Jared B. Smith   +9 more
doaj   +1 more source

Ramping activity in the striatum

Frontiers in Computational Neuroscience, 2022
Control of the timing of behavior is thought to require the basal ganglia (BG) and BG pathologies impair performance in timing tasks. Temporal interval discrimination depends on the ramping activity of medium spiny neurons (MSN) in the main BG input structure, the striatum, but the underlying mechanisms driving this activity are unclear.
Adam Ponzi, Jeff Wickens
openaire   +4 more sources