Results 31 to 40 of about 71,563 (292)

Oncomodulin: The Enigmatic Parvalbumin Protein [PDF]

open access: yesFrontiers in Molecular Neuroscience, 2019
EF-hand Ca2+-binding protein family members, α- and β-parvalbumins have been studied for decades. Yet, considerable information is lacking distinguishing functional differences between mammalian α-parvalbumin (PVALB) and oncomodulin (OCM), a branded β-parvalbumin.
Leslie K. Climer   +7 more
openaire   +3 more sources

Anatomical and molecular properties of long descending propriospinal neurons in mice [PDF]

open access: yes, 2017
Long descending propriospinal neurons (LDPNs) are interneurons that form direct connections between cervical and lumbar spinal circuits. LDPNs are involved in interlimb coordination and are important mediators of functional recovery after spinal cord ...
Boyle, Kieran   +8 more
core   +1 more source

Parvalbumin in rat kidney [PDF]

open access: yesFEBS Letters, 1986
The Ca2+‐binding parvalbumin has been purified for the first time from rat kidney. Its biochemical and immunological properties were indistinguishable from the muscle counterpart. By immunohistochemical methods parvalbumin was localized in part of the distal tubule and proximal collecting duct, similar to the vitamin D‐dependent Ca2+‐binding protein ...
Schneeberger, Peter R.   +1 more
openaire   +2 more sources

Calretinin as a marker for premotor neurons involved in upgaze in human brainstem

open access: yesFrontiers in Neuroanatomy, 2015
Eye movements are generated by different premotor pathways. Damage to them can cause specific deficits of eye movements, such as saccades. For correlative clinico-anatomical post-mortem studies of cases with eye movement disorders it is essential to ...
Christopher eAdamczyk   +6 more
doaj   +1 more source

TNFα induces Ca2+ influx to accelerate extrinsic apoptosis in hepatocellular carcinoma cells [PDF]

open access: yes, 2018
BACKGROUND: Tumor necrosis factor-α has been proven an effective anticancer agent in preclinical studies. However, the translation of TNFα from research to clinic has been blocked by significant systemic toxicity and limited efficacy at maximal tolerated
Ji, Xiaoying   +10 more
core   +4 more sources

Anxious Profile Influences Behavioral and Immunohistological Findings in the Pilocarpine Model of Epilepsy

open access: yesFrontiers in Pharmacology, 2021
Anxiety and epilepsy have a complex bidirectional relationship, where a depressive/anxious condition is a factor that can trigger seizures which in turn can aggravate the depressive/anxious condition. In addition, brain structures such as the hippocampus
Silvia Regina Bica Kohek   +7 more
doaj   +1 more source

Parvalbumin neurons in the forebrain as revealed by parvalbumin-Cre transgenic mice

open access: yesNeuroscience Research, 2009
Neurons expressing the calcium-binding protein parvalbumin (PV) constitute an abundant subpopulation of GABAergic neurons in the cerebral cortex. However, PV is not unique to the GABAergic neurons of the forebrain, but is also expressed in a small number of pyramidal neurons and in a large number of thalamic neurons.
Chiyoko, Tanahira   +6 more
openaire   +2 more sources

Postnatal development of thalamic reticular nucleus projections to the anterior thalamic nuclei in rats

open access: yesEuropean Journal of Histochemistry, 2022
The thalamic reticular nucleus (TRN) projects inhibitory signals to the thalamus, thereby controlling thalamocortical connections. Few studies have examined the development of TRN projections to the anterior thalamic nuclei with regard to axon course ...
Hitoshi Fujita   +3 more
doaj   +1 more source

Altered Disrupted-in-Schizophrenia-1 Function Affects the Development of Cortical Parvalbumin Interneurons by an Indirect Mechanism.

open access: yesPLoS ONE, 2016
Disrupted-in-Schizophrenia-1 (DISC1) gene has been linked to schizophrenia and related major mental illness. Mouse Disc1 has been implicated in brain development, mainly in the proliferation, differentiation, lamination, neurite outgrowth and synapse ...
Malgorzata Borkowska   +2 more
doaj   +1 more source

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